radir package: an R implementation for cytogenetic biodosimetry dose estimation
Standard
radir package: an R implementation for cytogenetic biodosimetry dose estimation. / Moriña, David; Higueras, Manuel; Puig, Pedro; Ainsbury, Elizabeth A; Rothkamm, Kai.
in: J RADIOL PROT, Jahrgang 35, Nr. 3, 10.07.2015, S. 557-569.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - radir package: an R implementation for cytogenetic biodosimetry dose estimation
AU - Moriña, David
AU - Higueras, Manuel
AU - Puig, Pedro
AU - Ainsbury, Elizabeth A
AU - Rothkamm, Kai
PY - 2015/7/10
Y1 - 2015/7/10
N2 - The Bayesian framework has been shown to be very useful in cytogenetic dose estimation. This approach allows description of the probability of an event in terms of previous knowledge, e.g. its expectation and/or its uncertainty. A new R package entitled radir (radiation inverse regression) has been implemented with the aim of reproducing a recent Bayesian-type dose estimation methodology. radir adopts the method of dose estimation under the Poisson assumption of the responses (the chromosomal aberrations counts) for the required dose-response curve (typically linear or quadratic). The individual commands are described in detail and relevant examples of the use of the methods and the corresponding radir software tools are given. The suitability of this methodology is highlighted and its application encouraged by providing a user-friendly command-type software interface within the R statistical software (version 3.1.1 or higher), which includes a complete manual.
AB - The Bayesian framework has been shown to be very useful in cytogenetic dose estimation. This approach allows description of the probability of an event in terms of previous knowledge, e.g. its expectation and/or its uncertainty. A new R package entitled radir (radiation inverse regression) has been implemented with the aim of reproducing a recent Bayesian-type dose estimation methodology. radir adopts the method of dose estimation under the Poisson assumption of the responses (the chromosomal aberrations counts) for the required dose-response curve (typically linear or quadratic). The individual commands are described in detail and relevant examples of the use of the methods and the corresponding radir software tools are given. The suitability of this methodology is highlighted and its application encouraged by providing a user-friendly command-type software interface within the R statistical software (version 3.1.1 or higher), which includes a complete manual.
U2 - 10.1088/0952-4746/35/3/557
DO - 10.1088/0952-4746/35/3/557
M3 - SCORING: Journal article
C2 - 26160852
VL - 35
SP - 557
EP - 569
JO - J RADIOL PROT
JF - J RADIOL PROT
SN - 0952-4746
IS - 3
ER -