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Radiotherapy of the rhabdomyosarcoma R1H of the rat: recovery from radiation injury in tumour and skin.

Standard

Radiotherapy of the rhabdomyosarcoma R1H of the rat: recovery from radiation injury in tumour and skin. / Würschmidt, F; Becker, S; Maurer, T; Omniczynski, M; Schelp, R; Vogler, H; Beck-Bornholdt, Hans-Peter.

in: RADIOTHER ONCOL, Jahrgang 23, Nr. 2, 2, 1992, S. 105-110.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Würschmidt, F, Becker, S, Maurer, T, Omniczynski, M, Schelp, R, Vogler, H & Beck-Bornholdt, H-P 1992, 'Radiotherapy of the rhabdomyosarcoma R1H of the rat: recovery from radiation injury in tumour and skin.', RADIOTHER ONCOL, Jg. 23, Nr. 2, 2, S. 105-110. <http://www.ncbi.nlm.nih.gov/pubmed/1546185?dopt=Citation>

APA

Würschmidt, F., Becker, S., Maurer, T., Omniczynski, M., Schelp, R., Vogler, H., & Beck-Bornholdt, H-P. (1992). Radiotherapy of the rhabdomyosarcoma R1H of the rat: recovery from radiation injury in tumour and skin. RADIOTHER ONCOL, 23(2), 105-110. [2]. http://www.ncbi.nlm.nih.gov/pubmed/1546185?dopt=Citation

Vancouver

Würschmidt F, Becker S, Maurer T, Omniczynski M, Schelp R, Vogler H et al. Radiotherapy of the rhabdomyosarcoma R1H of the rat: recovery from radiation injury in tumour and skin. RADIOTHER ONCOL. 1992;23(2):105-110. 2.

Bibtex

@article{fb4e7750a85d4379ab069d6579e37c69,
title = "Radiotherapy of the rhabdomyosarcoma R1H of the rat: recovery from radiation injury in tumour and skin.",
abstract = "The response of the rhabdomyosarcoma R1H of the rat to fractionated irradiation has been reported to be almost independent of the dose per fraction in the range from 0.43 to 10 Gy. To elucidate whether recovery from radiation injury is impaired in fractionated irradiation or not, tumours were exposed on 5 days per week over 6 weeks either to a single daily dose or to two daily fractions separated by an interfraction interval of 2 h. Tumour response was assessed by net growth delay. Skin damage was scored for comparison. A significant reduction in tumour response (p less than 0.009) and skin damage (p less than 0.001) was observed when the daily dose was administered in a twice daily irradiation regimen, indicating that recovery from radiation injury does occur in the course of fractionated irradiation in our tumour system. A tumour response was almost independent of the dose per fraction for time intervals between fractions of at least 8 h, a possible explanation might be that recovery is compensated by improved reoxygenation.",
author = "F W{\"u}rschmidt and S Becker and T Maurer and M Omniczynski and R Schelp and H Vogler and Hans-Peter Beck-Bornholdt",
year = "1992",
language = "Deutsch",
volume = "23",
pages = "105--110",
journal = "RADIOTHER ONCOL",
issn = "0167-8140",
publisher = "Elsevier Ireland Ltd",
number = "2",

}

RIS

TY - JOUR

T1 - Radiotherapy of the rhabdomyosarcoma R1H of the rat: recovery from radiation injury in tumour and skin.

AU - Würschmidt, F

AU - Becker, S

AU - Maurer, T

AU - Omniczynski, M

AU - Schelp, R

AU - Vogler, H

AU - Beck-Bornholdt, Hans-Peter

PY - 1992

Y1 - 1992

N2 - The response of the rhabdomyosarcoma R1H of the rat to fractionated irradiation has been reported to be almost independent of the dose per fraction in the range from 0.43 to 10 Gy. To elucidate whether recovery from radiation injury is impaired in fractionated irradiation or not, tumours were exposed on 5 days per week over 6 weeks either to a single daily dose or to two daily fractions separated by an interfraction interval of 2 h. Tumour response was assessed by net growth delay. Skin damage was scored for comparison. A significant reduction in tumour response (p less than 0.009) and skin damage (p less than 0.001) was observed when the daily dose was administered in a twice daily irradiation regimen, indicating that recovery from radiation injury does occur in the course of fractionated irradiation in our tumour system. A tumour response was almost independent of the dose per fraction for time intervals between fractions of at least 8 h, a possible explanation might be that recovery is compensated by improved reoxygenation.

AB - The response of the rhabdomyosarcoma R1H of the rat to fractionated irradiation has been reported to be almost independent of the dose per fraction in the range from 0.43 to 10 Gy. To elucidate whether recovery from radiation injury is impaired in fractionated irradiation or not, tumours were exposed on 5 days per week over 6 weeks either to a single daily dose or to two daily fractions separated by an interfraction interval of 2 h. Tumour response was assessed by net growth delay. Skin damage was scored for comparison. A significant reduction in tumour response (p less than 0.009) and skin damage (p less than 0.001) was observed when the daily dose was administered in a twice daily irradiation regimen, indicating that recovery from radiation injury does occur in the course of fractionated irradiation in our tumour system. A tumour response was almost independent of the dose per fraction for time intervals between fractions of at least 8 h, a possible explanation might be that recovery is compensated by improved reoxygenation.

M3 - SCORING: Zeitschriftenaufsatz

VL - 23

SP - 105

EP - 110

JO - RADIOTHER ONCOL

JF - RADIOTHER ONCOL

SN - 0167-8140

IS - 2

M1 - 2

ER -