PortalPublikationen"Race for the Surface"

"Race for the Surface"

Standard

"Race for the Surface" : Eukaryotic Cells Can Win. / Pham, Vy T H; Truong, Vi Khanh; Orlowska, Anna; Ghanaati, Shahram; Barbeck, Mike; Booms, Patrick; Fulcher, Alex J; Bhadra, Chris M; Buividas, Ričardas; Baulin, Vladimir; Kirkpatrick, C James; Doran, Pauline; Mainwaring, David E; Juodkazis, Saulius; Crawford, Russell J; Ivanova, Elena P.

in: ACS APPL MATER INTER, Jahrgang 8, Nr. 34, 31.08.2016, S. 22025-31.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Pham, VTH, Truong, VK, Orlowska, A, Ghanaati, S, Barbeck, M, Booms, P, Fulcher, AJ, Bhadra, CM, Buividas, R, Baulin, V, Kirkpatrick, CJ, Doran, P, Mainwaring, DE, Juodkazis, S, Crawford, RJ & Ivanova, EP 2016, '"Race for the Surface": Eukaryotic Cells Can Win', ACS APPL MATER INTER, Jg. 8, Nr. 34, S. 22025-31. https://doi.org/10.1021/acsami.6b06415

APA

Pham, V. T. H., Truong, V. K., Orlowska, A., Ghanaati, S., Barbeck, M., Booms, P., Fulcher, A. J., Bhadra, C. M., Buividas, R., Baulin, V., Kirkpatrick, C. J., Doran, P., Mainwaring, D. E., Juodkazis, S., Crawford, R. J., & Ivanova, E. P. (2016). "Race for the Surface": Eukaryotic Cells Can Win. ACS APPL MATER INTER, 8(34), 22025-31. https://doi.org/10.1021/acsami.6b06415

Vancouver

Pham VTH, Truong VK, Orlowska A, Ghanaati S, Barbeck M, Booms P et al. "Race for the Surface": Eukaryotic Cells Can Win. ACS APPL MATER INTER. 2016 Aug 31;8(34):22025-31. https://doi.org/10.1021/acsami.6b06415

Bibtex

@article{b1a5f901403b4dee8ac50796254fddab,
title = "{"}Race for the Surface{"}: Eukaryotic Cells Can Win",
abstract = "With an aging population and the consequent increasing use of medical implants, managing the possible infections arising from implant surgery remains a global challenge. Here, we demonstrate for the first time that a precise nanotopology provides an effective intervention in bacterial cocolonization enabling the proliferation of eukaryotic cells on a substratum surface, preinfected by both live Gram-negative, Pseudomonas aeruginosa, and Gram-positive, Staphylococcus aureus, pathogenic bacteria. The topology of the model black silicon (bSi) substratum not only favors the proliferation of eukaryotic cells but is biocompatible, not triggering an inflammatory response in the host. The attachment behavior and development of filopodia when COS-7 fibroblast cells are placed in contact with the bSi surface are demonstrated in the dynamic study, which is based on the use of real-time sequential confocal imaging. Bactericidal nanotopology may enhance the prospect for further development of inherently responsive antibacterial nanomaterials for bionic applications such as prosthetics and implants. ",
keywords = "Anti-Bacterial Agents, Eukaryotic Cells, Nanostructures, Pseudomonas aeruginosa, Staphylococcus aureus, Surface Properties, Journal Article",
author = "Pham, {Vy T H} and Truong, {Vi Khanh} and Anna Orlowska and Shahram Ghanaati and Mike Barbeck and Patrick Booms and Fulcher, {Alex J} and Bhadra, {Chris M} and Ri{\v c}ardas Buividas and Vladimir Baulin and Kirkpatrick, {C James} and Pauline Doran and Mainwaring, {David E} and Saulius Juodkazis and Crawford, {Russell J} and Ivanova, {Elena P}",
year = "2016",
month = aug,
day = "31",
doi = "10.1021/acsami.6b06415",
language = "English",
volume = "8",
pages = "22025--31",
journal = "ACS APPL MATER INTER",
issn = "1944-8244",
publisher = "American Chemical Society",
number = "34",

}

RIS

TY - JOUR

T1 - "Race for the Surface"

T2 - Eukaryotic Cells Can Win

AU - Pham, Vy T H

AU - Truong, Vi Khanh

AU - Orlowska, Anna

AU - Ghanaati, Shahram

AU - Barbeck, Mike

AU - Booms, Patrick

AU - Fulcher, Alex J

AU - Bhadra, Chris M

AU - Buividas, Ričardas

AU - Baulin, Vladimir

AU - Kirkpatrick, C James

AU - Doran, Pauline

AU - Mainwaring, David E

AU - Juodkazis, Saulius

AU - Crawford, Russell J

AU - Ivanova, Elena P

PY - 2016/8/31

Y1 - 2016/8/31

N2 - With an aging population and the consequent increasing use of medical implants, managing the possible infections arising from implant surgery remains a global challenge. Here, we demonstrate for the first time that a precise nanotopology provides an effective intervention in bacterial cocolonization enabling the proliferation of eukaryotic cells on a substratum surface, preinfected by both live Gram-negative, Pseudomonas aeruginosa, and Gram-positive, Staphylococcus aureus, pathogenic bacteria. The topology of the model black silicon (bSi) substratum not only favors the proliferation of eukaryotic cells but is biocompatible, not triggering an inflammatory response in the host. The attachment behavior and development of filopodia when COS-7 fibroblast cells are placed in contact with the bSi surface are demonstrated in the dynamic study, which is based on the use of real-time sequential confocal imaging. Bactericidal nanotopology may enhance the prospect for further development of inherently responsive antibacterial nanomaterials for bionic applications such as prosthetics and implants.

AB - With an aging population and the consequent increasing use of medical implants, managing the possible infections arising from implant surgery remains a global challenge. Here, we demonstrate for the first time that a precise nanotopology provides an effective intervention in bacterial cocolonization enabling the proliferation of eukaryotic cells on a substratum surface, preinfected by both live Gram-negative, Pseudomonas aeruginosa, and Gram-positive, Staphylococcus aureus, pathogenic bacteria. The topology of the model black silicon (bSi) substratum not only favors the proliferation of eukaryotic cells but is biocompatible, not triggering an inflammatory response in the host. The attachment behavior and development of filopodia when COS-7 fibroblast cells are placed in contact with the bSi surface are demonstrated in the dynamic study, which is based on the use of real-time sequential confocal imaging. Bactericidal nanotopology may enhance the prospect for further development of inherently responsive antibacterial nanomaterials for bionic applications such as prosthetics and implants.

KW - Anti-Bacterial Agents

KW - Eukaryotic Cells

KW - Nanostructures

KW - Pseudomonas aeruginosa

KW - Staphylococcus aureus

KW - Surface Properties

KW - Journal Article

U2 - 10.1021/acsami.6b06415

DO - 10.1021/acsami.6b06415

M3 - SCORING: Journal article

C2 - 27494044

VL - 8

SP - 22025

EP - 22031

JO - ACS APPL MATER INTER

JF - ACS APPL MATER INTER

SN - 1944-8244

IS - 34

ER -