Quantification of the Proportion of Unfavorable Clinical Outcomes among Imported Malaria Patients According to the Degree of Semi-Immunity on Population Level: An Ecological Study
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Quantification of the Proportion of Unfavorable Clinical Outcomes among Imported Malaria Patients According to the Degree of Semi-Immunity on Population Level: An Ecological Study. / Nordmann, Tamara; Davi, Saskia Dede; Ramharter, Michael; Mischlinger, Johannes.
in: AM J TROP MED HYG, Jahrgang 105, Nr. 2, 14.06.2021, S. 477-479.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung
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TY - JOUR
T1 - Quantification of the Proportion of Unfavorable Clinical Outcomes among Imported Malaria Patients According to the Degree of Semi-Immunity on Population Level: An Ecological Study
AU - Nordmann, Tamara
AU - Davi, Saskia Dede
AU - Ramharter, Michael
AU - Mischlinger, Johannes
PY - 2021/6/14
Y1 - 2021/6/14
N2 - The protective effect of semi-immunity to alleviate clinical complications of malaria remains incompletely understood. This ecological study quantified the proportion of unfavorable clinical outcomes among patient populations with imported malaria as a function of the reported proportion of absent semi-immunity in a patient population. Group-level proportions were extracted from published studies on imported malaria. Linear regression analyses demonstrate a consistent positive trend between the average proportion of absent semi-immunity in patient populations of imported malaria and the proportion of unfavorable clinical outcomes therein. Regression equations provide a group-level estimate of attributable fractions of clinical complications resulting from absent semi-immunity to malaria.
AB - The protective effect of semi-immunity to alleviate clinical complications of malaria remains incompletely understood. This ecological study quantified the proportion of unfavorable clinical outcomes among patient populations with imported malaria as a function of the reported proportion of absent semi-immunity in a patient population. Group-level proportions were extracted from published studies on imported malaria. Linear regression analyses demonstrate a consistent positive trend between the average proportion of absent semi-immunity in patient populations of imported malaria and the proportion of unfavorable clinical outcomes therein. Regression equations provide a group-level estimate of attributable fractions of clinical complications resulting from absent semi-immunity to malaria.
KW - Antimalarials/therapeutic use
KW - Chemoprevention
KW - Communicable Diseases, Imported/epidemiology
KW - Humans
KW - Immunity
KW - Malaria/drug therapy
KW - Medication Adherence
KW - Mortality
KW - Plasmodium/immunology
KW - Population Surveillance
KW - Prevalence
KW - Travel
KW - Treatment Outcome
U2 - 10.4269/ajtmh.21-0196
DO - 10.4269/ajtmh.21-0196
M3 - SCORING: Review article
C2 - 34125702
VL - 105
SP - 477
EP - 479
JO - AM J TROP MED HYG
JF - AM J TROP MED HYG
SN - 0002-9637
IS - 2
ER -