Quantification of the Proportion of Unfavorable Clinical Outcomes among Imported Malaria Patients According to the Degree of Semi-Immunity on Population Level: An Ecological Study

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Quantification of the Proportion of Unfavorable Clinical Outcomes among Imported Malaria Patients According to the Degree of Semi-Immunity on Population Level: An Ecological Study. / Nordmann, Tamara; Davi, Saskia Dede; Ramharter, Michael; Mischlinger, Johannes.

in: AM J TROP MED HYG, Jahrgang 105, Nr. 2, 14.06.2021, S. 477-479.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ReviewForschung

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@article{06388dd89d9e44c7b9fb7b4fb6205c09,
title = "Quantification of the Proportion of Unfavorable Clinical Outcomes among Imported Malaria Patients According to the Degree of Semi-Immunity on Population Level: An Ecological Study",
abstract = "The protective effect of semi-immunity to alleviate clinical complications of malaria remains incompletely understood. This ecological study quantified the proportion of unfavorable clinical outcomes among patient populations with imported malaria as a function of the reported proportion of absent semi-immunity in a patient population. Group-level proportions were extracted from published studies on imported malaria. Linear regression analyses demonstrate a consistent positive trend between the average proportion of absent semi-immunity in patient populations of imported malaria and the proportion of unfavorable clinical outcomes therein. Regression equations provide a group-level estimate of attributable fractions of clinical complications resulting from absent semi-immunity to malaria.",
keywords = "Antimalarials/therapeutic use, Chemoprevention, Communicable Diseases, Imported/epidemiology, Humans, Immunity, Malaria/drug therapy, Medication Adherence, Mortality, Plasmodium/immunology, Population Surveillance, Prevalence, Travel, Treatment Outcome",
author = "Tamara Nordmann and Davi, {Saskia Dede} and Michael Ramharter and Johannes Mischlinger",
year = "2021",
month = jun,
day = "14",
doi = "10.4269/ajtmh.21-0196",
language = "English",
volume = "105",
pages = "477--479",
journal = "AM J TROP MED HYG",
issn = "0002-9637",
publisher = "American Society of Tropical Medicine and Hygiene",
number = "2",

}

RIS

TY - JOUR

T1 - Quantification of the Proportion of Unfavorable Clinical Outcomes among Imported Malaria Patients According to the Degree of Semi-Immunity on Population Level: An Ecological Study

AU - Nordmann, Tamara

AU - Davi, Saskia Dede

AU - Ramharter, Michael

AU - Mischlinger, Johannes

PY - 2021/6/14

Y1 - 2021/6/14

N2 - The protective effect of semi-immunity to alleviate clinical complications of malaria remains incompletely understood. This ecological study quantified the proportion of unfavorable clinical outcomes among patient populations with imported malaria as a function of the reported proportion of absent semi-immunity in a patient population. Group-level proportions were extracted from published studies on imported malaria. Linear regression analyses demonstrate a consistent positive trend between the average proportion of absent semi-immunity in patient populations of imported malaria and the proportion of unfavorable clinical outcomes therein. Regression equations provide a group-level estimate of attributable fractions of clinical complications resulting from absent semi-immunity to malaria.

AB - The protective effect of semi-immunity to alleviate clinical complications of malaria remains incompletely understood. This ecological study quantified the proportion of unfavorable clinical outcomes among patient populations with imported malaria as a function of the reported proportion of absent semi-immunity in a patient population. Group-level proportions were extracted from published studies on imported malaria. Linear regression analyses demonstrate a consistent positive trend between the average proportion of absent semi-immunity in patient populations of imported malaria and the proportion of unfavorable clinical outcomes therein. Regression equations provide a group-level estimate of attributable fractions of clinical complications resulting from absent semi-immunity to malaria.

KW - Antimalarials/therapeutic use

KW - Chemoprevention

KW - Communicable Diseases, Imported/epidemiology

KW - Humans

KW - Immunity

KW - Malaria/drug therapy

KW - Medication Adherence

KW - Mortality

KW - Plasmodium/immunology

KW - Population Surveillance

KW - Prevalence

KW - Travel

KW - Treatment Outcome

U2 - 10.4269/ajtmh.21-0196

DO - 10.4269/ajtmh.21-0196

M3 - SCORING: Review article

C2 - 34125702

VL - 105

SP - 477

EP - 479

JO - AM J TROP MED HYG

JF - AM J TROP MED HYG

SN - 0002-9637

IS - 2

ER -