Quantification of recurrence volumes after endovascular treatment of cerebral aneurysm as surrogate endpoint for treatment stability.
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Quantification of recurrence volumes after endovascular treatment of cerebral aneurysm as surrogate endpoint for treatment stability. / Ries, Thorsten; Wegscheider, Karl; Wulff, Asmus; Radelfahr, Kristin; Säring, Dennis; Forkert, Nils; Fiehler, Jens.
in: NEURORADIOLOGY, Jahrgang 53, Nr. 8, 8, 2011, S. 593-598.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Quantification of recurrence volumes after endovascular treatment of cerebral aneurysm as surrogate endpoint for treatment stability.
AU - Ries, Thorsten
AU - Wegscheider, Karl
AU - Wulff, Asmus
AU - Radelfahr, Kristin
AU - Säring, Dennis
AU - Forkert, Nils
AU - Fiehler, Jens
PY - 2011
Y1 - 2011
N2 - New coils with unproven clinical benefit enlarge the armamentarium for endovascular aneurysm treatment continuously. Large patient numbers needed to detect benefits of such new techniques prevent timely evaluation of efficacy. We propose measuring the volume of aneurysm recurrences as surrogate endpoint for coil stability. We hypothesize that this method allows detecting effects of new materials with reduced sample sizes in comparison to conventional studies with dichotomous endpoints.
AB - New coils with unproven clinical benefit enlarge the armamentarium for endovascular aneurysm treatment continuously. Large patient numbers needed to detect benefits of such new techniques prevent timely evaluation of efficacy. We propose measuring the volume of aneurysm recurrences as surrogate endpoint for coil stability. We hypothesize that this method allows detecting effects of new materials with reduced sample sizes in comparison to conventional studies with dichotomous endpoints.
M3 - SCORING: Journal article
VL - 53
SP - 593
EP - 598
JO - NEURORADIOLOGY
JF - NEURORADIOLOGY
SN - 0028-3940
IS - 8
M1 - 8
ER -