Quality of life several years after myocardial infarction: comparing the MONICA/KORA registry to the general population.
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Quality of life several years after myocardial infarction: comparing the MONICA/KORA registry to the general population. / Schweikert, Bernd; Hunger, Matthias; Meisinger, Christa; König, Hans-Helmut; Gapp, Oliver; Holle, Rolf.
in: EUR HEART J, Jahrgang 30, Nr. 4, 4, 2009, S. 436-443.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Quality of life several years after myocardial infarction: comparing the MONICA/KORA registry to the general population.
AU - Schweikert, Bernd
AU - Hunger, Matthias
AU - Meisinger, Christa
AU - König, Hans-Helmut
AU - Gapp, Oliver
AU - Holle, Rolf
PY - 2009
Y1 - 2009
N2 - AIMS: The aim of this study was to assess the impact of myocardial infarction (MI) on health-related quality of life (HRQL) in MI survivors measured by EuroQol (EQ-5D) and to compare it with the general population. METHODS AND RESULTS: A follow-up study of all MI survivors included in the MONICA/KORA registry was performed. About 2950 (67.1%) patients responded. Moderate or severe problems were most frequent in EQ-5D dimension pain/discomfort (55.0%), anxiety/depression (29.2%), and mobility (27.9%). Mean EQ VAS score was 65.8 (SD 18.5). Main predictors of lower HRQL included older age, diabetes, increasing body mass index, current smoking, and experience of re-infarction. Type of revascularizational treatment showed no impact on HRQL. Compared with the general population, adjusted EQ VAS was 6.2 (95% confidence interval 3.4-8.9) points lower in 45-year-old MI patients converging with growing age up to the age of 80. With regard to HRQL dimensions, MI survivors had a significantly higher risk of incurring problems in the dimension pain/discomfort, usual activities, and especially in anxiety/depression which was more pronounced in younger age. Mobility was the single dimension, in which MI showed an inverse effect. CONCLUSION: MI is combined with significant reduction in HRQL compared with the general population. The main impairments occur in the dimension pain/discomfort, usual activities, and particularly anxiety/depression. The relative impairment decreases with higher ages.
AB - AIMS: The aim of this study was to assess the impact of myocardial infarction (MI) on health-related quality of life (HRQL) in MI survivors measured by EuroQol (EQ-5D) and to compare it with the general population. METHODS AND RESULTS: A follow-up study of all MI survivors included in the MONICA/KORA registry was performed. About 2950 (67.1%) patients responded. Moderate or severe problems were most frequent in EQ-5D dimension pain/discomfort (55.0%), anxiety/depression (29.2%), and mobility (27.9%). Mean EQ VAS score was 65.8 (SD 18.5). Main predictors of lower HRQL included older age, diabetes, increasing body mass index, current smoking, and experience of re-infarction. Type of revascularizational treatment showed no impact on HRQL. Compared with the general population, adjusted EQ VAS was 6.2 (95% confidence interval 3.4-8.9) points lower in 45-year-old MI patients converging with growing age up to the age of 80. With regard to HRQL dimensions, MI survivors had a significantly higher risk of incurring problems in the dimension pain/discomfort, usual activities, and especially in anxiety/depression which was more pronounced in younger age. Mobility was the single dimension, in which MI showed an inverse effect. CONCLUSION: MI is combined with significant reduction in HRQL compared with the general population. The main impairments occur in the dimension pain/discomfort, usual activities, and particularly anxiety/depression. The relative impairment decreases with higher ages.
KW - Adult
KW - Germany
KW - Humans
KW - Male
KW - Aged
KW - Female
KW - Middle Aged
KW - Activities of Daily Living
KW - Aged, 80 and over
KW - Quality of Life
KW - Questionnaires
KW - Body Mass Index
KW - Depressive Disorder etiology
KW - Epidemiologic Methods
KW - Myocardial Infarction complications
KW - Myocardial Reperfusion methods
KW - Pain etiology
KW - Registries
KW - Survivors
KW - Adult
KW - Germany
KW - Humans
KW - Male
KW - Aged
KW - Female
KW - Middle Aged
KW - Activities of Daily Living
KW - Aged, 80 and over
KW - Quality of Life
KW - Questionnaires
KW - Body Mass Index
KW - Depressive Disorder etiology
KW - Epidemiologic Methods
KW - Myocardial Infarction complications
KW - Myocardial Reperfusion methods
KW - Pain etiology
KW - Registries
KW - Survivors
M3 - SCORING: Zeitschriftenaufsatz
VL - 30
SP - 436
EP - 443
JO - EUR HEART J
JF - EUR HEART J
SN - 0195-668X
IS - 4
M1 - 4
ER -
