Quality of Life in Psoriasis Vulgaris: Use of the ItchyQoL Question-naire in a Secukinumab Phase III Trial in Patients with Psoriasis Vulgaris

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Quality of Life in Psoriasis Vulgaris: Use of the ItchyQoL Question-naire in a Secukinumab Phase III Trial in Patients with Psoriasis Vulgaris. / Ständer, Sonja; Steinke, Sabine; Augustin, Matthias; Metze, Dieter; Loser, Karin; Baeumer, Daniel; Sieder, Christian; Luger, Thomas.

in: ACTA DERM-VENEREOL, Jahrgang 99, Nr. 12, 01.11.2019, S. 1085-1090.

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@article{4b225f72493345b68a415fdc8d7950b9,
title = "Quality of Life in Psoriasis Vulgaris: Use of the ItchyQoL Question-naire in a Secukinumab Phase III Trial in Patients with Psoriasis Vulgaris",
abstract = "Chronic pruritus is a bothersome symptom in psoriasis vulgaris and can profoundly reduce quality of life (QoL). In this exploratory analysis of the PSORITUS study, the impact of pruritus on QoL in 130 subjects with moderate-to-severe psoriasis was assessed using the ItchyQoL questionnaire. The majority of patients (n = 127) had to scratch their itchy skin regularly, which led to painful skin and frustration (mean ± standard deviation; SD ItchyQoL scores; 4.50 ± 0.56; 3.80 ± 1.09 and 4.20 ± 0.87, respectively). Changes in either temperature or season led to a worsening of itching in most of the patients (n = 126; mean ± SD ItchyQoL score; 3.80 ± 1.02). Many patients felt ashamed (n = 125) or embarrassed (n = 127) due to their itchy skin (mean ± SD ItchyQoL scores; 3.90 ± 1.26 and 3.40 ± 1.19, respectively). The results demonstrated the ItchyQoL questionnaire as a validated tool responsive to treatment for detailed insights into chronic pruritus in patients with psoriasis.",
author = "Sonja St{\"a}nder and Sabine Steinke and Matthias Augustin and Dieter Metze and Karin Loser and Daniel Baeumer and Christian Sieder and Thomas Luger",
year = "2019",
month = nov,
day = "1",
doi = "10.2340/00015555-3275",
language = "English",
volume = "99",
pages = "1085--1090",
journal = "ACTA DERM-VENEREOL",
issn = "0001-5555",
publisher = "Society for the Publication of Acta Dermato-Venereologica",
number = "12",

}

RIS

TY - JOUR

T1 - Quality of Life in Psoriasis Vulgaris: Use of the ItchyQoL Question-naire in a Secukinumab Phase III Trial in Patients with Psoriasis Vulgaris

AU - Ständer, Sonja

AU - Steinke, Sabine

AU - Augustin, Matthias

AU - Metze, Dieter

AU - Loser, Karin

AU - Baeumer, Daniel

AU - Sieder, Christian

AU - Luger, Thomas

PY - 2019/11/1

Y1 - 2019/11/1

N2 - Chronic pruritus is a bothersome symptom in psoriasis vulgaris and can profoundly reduce quality of life (QoL). In this exploratory analysis of the PSORITUS study, the impact of pruritus on QoL in 130 subjects with moderate-to-severe psoriasis was assessed using the ItchyQoL questionnaire. The majority of patients (n = 127) had to scratch their itchy skin regularly, which led to painful skin and frustration (mean ± standard deviation; SD ItchyQoL scores; 4.50 ± 0.56; 3.80 ± 1.09 and 4.20 ± 0.87, respectively). Changes in either temperature or season led to a worsening of itching in most of the patients (n = 126; mean ± SD ItchyQoL score; 3.80 ± 1.02). Many patients felt ashamed (n = 125) or embarrassed (n = 127) due to their itchy skin (mean ± SD ItchyQoL scores; 3.90 ± 1.26 and 3.40 ± 1.19, respectively). The results demonstrated the ItchyQoL questionnaire as a validated tool responsive to treatment for detailed insights into chronic pruritus in patients with psoriasis.

AB - Chronic pruritus is a bothersome symptom in psoriasis vulgaris and can profoundly reduce quality of life (QoL). In this exploratory analysis of the PSORITUS study, the impact of pruritus on QoL in 130 subjects with moderate-to-severe psoriasis was assessed using the ItchyQoL questionnaire. The majority of patients (n = 127) had to scratch their itchy skin regularly, which led to painful skin and frustration (mean ± standard deviation; SD ItchyQoL scores; 4.50 ± 0.56; 3.80 ± 1.09 and 4.20 ± 0.87, respectively). Changes in either temperature or season led to a worsening of itching in most of the patients (n = 126; mean ± SD ItchyQoL score; 3.80 ± 1.02). Many patients felt ashamed (n = 125) or embarrassed (n = 127) due to their itchy skin (mean ± SD ItchyQoL scores; 3.90 ± 1.26 and 3.40 ± 1.19, respectively). The results demonstrated the ItchyQoL questionnaire as a validated tool responsive to treatment for detailed insights into chronic pruritus in patients with psoriasis.

U2 - 10.2340/00015555-3275

DO - 10.2340/00015555-3275

M3 - SCORING: Journal article

C2 - 31386163

VL - 99

SP - 1085

EP - 1090

JO - ACTA DERM-VENEREOL

JF - ACTA DERM-VENEREOL

SN - 0001-5555

IS - 12

ER -