Qualitative tissue differentiation by analysing the intensity ratios of atomic emission lines using laser induced breakdown spectroscopy (LIBS)

  • Rajesh Kanawade
  • Fanuel Mahari
  • Florian Klämpfl
  • Maximilian Rohde
  • Christian Knipfer
  • Katja Tangermann-Gerk
  • Werner Adler
  • Michael Schmidt
  • Florian Stelzle

Abstract

The research work presented in this paper focuses on qualitative tissue differentiation by monitoring the intensity ratios of atomic emissions using 'Laser Induced Breakdown Spectroscopy' (LIBS) on the plasma plume created during laser tissue ablation. The background of this study is to establish a real time feedback control mechanism for clinical laser surgery systems during the laser ablation process. Ex-vivo domestic pig tissue samples (muscle, fat, nerve and skin) were used in this experiment. Atomic emission intensity ratios were analyzed to find a characteristic spectral line for each tissue. The results showed characteristic elemental emission intensity ratios for the respective tissues. The spectral lines and intensity ratios of these specific elements varied among the different tissue types. The main goal of this study is to qualitatively and precisely identify different tissue types for tissue specific laser surgery.

Bibliografische Daten

OriginalspracheEnglisch
ISSN1864-063X
DOIs
StatusVeröffentlicht - 01.2015
Extern publiziertJa
PubMed 24376030