Psoriasis comorbidities in Germany: A population-based study on spatiotemporal variations
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Psoriasis comorbidities in Germany: A population-based study on spatiotemporal variations. / Augustin, Jobst; Wolf, Sandra; Stephan, Brigitte; Augustin, Matthias; Andrees, Valerie.
in: PLOS ONE, Jahrgang 17, Nr. 3, e0265741, 2022.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Psoriasis comorbidities in Germany: A population-based study on spatiotemporal variations
AU - Augustin, Jobst
AU - Wolf, Sandra
AU - Stephan, Brigitte
AU - Augustin, Matthias
AU - Andrees, Valerie
PY - 2022
Y1 - 2022
N2 - Psoriasis is a chronic disease with high impact on patients' health and their quality of life. Psoriasis often occurs along with other comorbidities, but it is not yet clear what role the comorbidities play in regional psoriasis prevalence. This study investigates the temporal and regional variation of the psoriasis comorbidities diabetes mellitus type II, obesity, hypertension, affective disorders in Germany and their association with psoriasis prevalence. This analysis based on the population set of ambulatory claims data (2010-2017) of the statutory health insurance (SHI) in Germany (approx. 70.3 million people in 2017). Psoriasis comorbidities rates were determined on county level. We performed descriptive spatiotemporal analyses of psoriasis comorbidity prevalence rates. In addition, we identified and compared spatial clusters and examined regional variations using spatial statistical methods. The results show strong regional variations (northeast to south gradient) and an increasing psoriasis prevalence (max. 28.8%) within the observation period. Considering the comorbidities, results indicate comparable spatial prevalence patterns for diabetes mellitus type II, obesity and hypertension. This means that the highest prevalence of comorbidities tends to be found where the psoriasis prevalence is highest. The spatiotemporal cluster analyses could once again confirm the results. An exception to this is to be found in the case of affective disorders with different spatial patterns. The results of the studies show the first spatiotemporal association between psoriasis prevalence and comorbidities in Germany. The causalities must be investigated in more detail in order to be able to derive measures for improved care.
AB - Psoriasis is a chronic disease with high impact on patients' health and their quality of life. Psoriasis often occurs along with other comorbidities, but it is not yet clear what role the comorbidities play in regional psoriasis prevalence. This study investigates the temporal and regional variation of the psoriasis comorbidities diabetes mellitus type II, obesity, hypertension, affective disorders in Germany and their association with psoriasis prevalence. This analysis based on the population set of ambulatory claims data (2010-2017) of the statutory health insurance (SHI) in Germany (approx. 70.3 million people in 2017). Psoriasis comorbidities rates were determined on county level. We performed descriptive spatiotemporal analyses of psoriasis comorbidity prevalence rates. In addition, we identified and compared spatial clusters and examined regional variations using spatial statistical methods. The results show strong regional variations (northeast to south gradient) and an increasing psoriasis prevalence (max. 28.8%) within the observation period. Considering the comorbidities, results indicate comparable spatial prevalence patterns for diabetes mellitus type II, obesity and hypertension. This means that the highest prevalence of comorbidities tends to be found where the psoriasis prevalence is highest. The spatiotemporal cluster analyses could once again confirm the results. An exception to this is to be found in the case of affective disorders with different spatial patterns. The results of the studies show the first spatiotemporal association between psoriasis prevalence and comorbidities in Germany. The causalities must be investigated in more detail in order to be able to derive measures for improved care.
KW - Comorbidity
KW - Diabetes Mellitus, Type 2/epidemiology
KW - Germany/epidemiology
KW - Humans
KW - Hypertension/epidemiology
KW - Obesity/epidemiology
KW - Prevalence
KW - Psoriasis/epidemiology
KW - Quality of Life
U2 - 10.1371/journal.pone.0265741
DO - 10.1371/journal.pone.0265741
M3 - SCORING: Journal article
C2 - 35316303
VL - 17
JO - PLOS ONE
JF - PLOS ONE
SN - 1932-6203
IS - 3
M1 - e0265741
ER -
