Psoriasis - The Life Course Approach

TY - JOUR

T1 - Psoriasis - The Life Course Approach

AU - Linder, Michael Dennis

AU - Piaserico, Stefano

AU - Augustin, Matthias

AU - Fortina, Anna Belloni

AU - Cohen, Arnon D

AU - Gieler, Uwe

AU - Jemec, Gregor B E

AU - Kimball, Alexa Boer

AU - Peserico, Andrea

AU - Sampogna, Francesca

AU - Warren, Richard B

AU - de Korte, John

PY - 2016/8/23

Y1 - 2016/8/23

N2 - Over the last decades, Life Course Research (LCR), predominantly the domain of sociology, has been increasingly applied in health research, as Life Course Epidemiology (LCE). The latter is concerned with disease patterns over time, accumulation of exposures over time, critical time periods and patterns of risk. We argue that concepts from LCR and LCE could be widely applied in dermatology, in general, and, more precisely, in the study of chronic inflammatory skin diseases, e.g. atopic eczema and psoriasis. The life course approach can generally be applied in two different ways. It may be used in the more traditional manner, in which the disease and its patterns over time are examined as the outcome vari-able. Conversely, it can examine life course as the outcome variable, which is dependent on the disease course, the treatments administered, and other physical or psychosocial environmental exposures. In dermatology, this second application of the LCR concepts is both promising and relevant because of the notable impact of chronic skin diseases on the patients' quality of life. In particular, we argue how LCR may be conducive to a better understanding of the concept of 'Cumulative Life Course Impairment', which is increasingly gaining acceptance. This approach helps identifying not only individuals at risk and particularly vulnerable patients but also critical periods for optimising interventions in order to avoid life course impairment. It also may facilitate more appropriate treatment decisions in clinical practice.

AB - Over the last decades, Life Course Research (LCR), predominantly the domain of sociology, has been increasingly applied in health research, as Life Course Epidemiology (LCE). The latter is concerned with disease patterns over time, accumulation of exposures over time, critical time periods and patterns of risk. We argue that concepts from LCR and LCE could be widely applied in dermatology, in general, and, more precisely, in the study of chronic inflammatory skin diseases, e.g. atopic eczema and psoriasis. The life course approach can generally be applied in two different ways. It may be used in the more traditional manner, in which the disease and its patterns over time are examined as the outcome vari-able. Conversely, it can examine life course as the outcome variable, which is dependent on the disease course, the treatments administered, and other physical or psychosocial environmental exposures. In dermatology, this second application of the LCR concepts is both promising and relevant because of the notable impact of chronic skin diseases on the patients' quality of life. In particular, we argue how LCR may be conducive to a better understanding of the concept of 'Cumulative Life Course Impairment', which is increasingly gaining acceptance. This approach helps identifying not only individuals at risk and particularly vulnerable patients but also critical periods for optimising interventions in order to avoid life course impairment. It also may facilitate more appropriate treatment decisions in clinical practice.

KW - Adaptation, Psychological

KW - Chronic Disease

KW - Cost of Illness

KW - Humans

KW - Life Change Events

KW - Psoriasis

KW - Quality of Life

KW - Journal Article

U2 - 10.2340/00015555-2430

DO - 10.2340/00015555-2430

M3 - SCORING: Journal article

C2 - 27283774

VL - 96

SP - 102

EP - 108

JO - ACTA DERM-VENEREOL

JF - ACTA DERM-VENEREOL

SN - 0001-5555

IS - 217

ER -