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Proteome analysis of human mesenchymal stem cells undergoing chondrogenesis when exposed to the products of various magnesium-based materials degradation

Standard

Proteome analysis of human mesenchymal stem cells undergoing chondrogenesis when exposed to the products of various magnesium-based materials degradation. / Martínez Sánchez, Adela Helvia; Omidi, Maryam; Wurlitzer, Marcus; Fuh, Marceline Manka; Feyerabend, Frank; Schlüter, Hartmut; Willumeit-Römer, Regine; Luthringer, Bérengère J C.

in: BIOACT MATER, Jahrgang 4, 12.2019, S. 168-188.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Martínez Sánchez, AH, Omidi, M, Wurlitzer, M, Fuh, MM, Feyerabend, F, Schlüter, H, Willumeit-Römer, R & Luthringer, BJC 2019, 'Proteome analysis of human mesenchymal stem cells undergoing chondrogenesis when exposed to the products of various magnesium-based materials degradation', BIOACT MATER, Jg. 4, S. 168-188. https://doi.org/10.1016/j.bioactmat.2019.04.001

APA

Martínez Sánchez, A. H., Omidi, M., Wurlitzer, M., Fuh, M. M., Feyerabend, F., Schlüter, H., Willumeit-Römer, R., & Luthringer, B. J. C. (2019). Proteome analysis of human mesenchymal stem cells undergoing chondrogenesis when exposed to the products of various magnesium-based materials degradation. BIOACT MATER, 4, 168-188. https://doi.org/10.1016/j.bioactmat.2019.04.001

Vancouver

Martínez Sánchez AH, Omidi M, Wurlitzer M, Fuh MM, Feyerabend F, Schlüter H et al. Proteome analysis of human mesenchymal stem cells undergoing chondrogenesis when exposed to the products of various magnesium-based materials degradation. BIOACT MATER. 2019 Dez;4:168-188. https://doi.org/10.1016/j.bioactmat.2019.04.001

Bibtex

@article{7c48d864493a4f3899b5f970cad6bdc0,
title = "Proteome analysis of human mesenchymal stem cells undergoing chondrogenesis when exposed to the products of various magnesium-based materials degradation",
abstract = "Treatment of physeal fractures (15%-30% of all paediatric fractures) remains a challenge as in approximately 10% of the cases, significant growth disturbance may occur. Bioresorbable Magnesium-based implants represent a strategy to minimize damage (i.e., load support until bone healing without second surgery). Nevertheless, the absence of harmful effects of magnesium-implants and their degradation products on the growth plate should be confirmed. Here, the proteome of human mesenchymal stem cells undergoing chondrogenesis was evaluated when exposed to the products of various Magnesium-based materials degradation. The results of this study indicate that the materials induced regulation of proteins associated with cell chondrogenesis and cartilage formation, which should be beneficial for cartilage regeneration.",
keywords = "Journal Article",
author = "{Mart{\'i}nez S{\'a}nchez}, {Adela Helvia} and Maryam Omidi and Marcus Wurlitzer and Fuh, {Marceline Manka} and Frank Feyerabend and Hartmut Schl{\"u}ter and Regine Willumeit-R{\"o}mer and Luthringer, {B{\'e}reng{\`e}re J C}",
year = "2019",
month = dec,
doi = "10.1016/j.bioactmat.2019.04.001",
language = "English",
volume = "4",
pages = "168--188",
journal = "BIOACT MATER",
issn = "2452-199X",
publisher = "KeAi Publishing Communications Ltd.",

}

RIS

TY - JOUR

T1 - Proteome analysis of human mesenchymal stem cells undergoing chondrogenesis when exposed to the products of various magnesium-based materials degradation

AU - Martínez Sánchez, Adela Helvia

AU - Omidi, Maryam

AU - Wurlitzer, Marcus

AU - Fuh, Marceline Manka

AU - Feyerabend, Frank

AU - Schlüter, Hartmut

AU - Willumeit-Römer, Regine

AU - Luthringer, Bérengère J C

PY - 2019/12

Y1 - 2019/12

N2 - Treatment of physeal fractures (15%-30% of all paediatric fractures) remains a challenge as in approximately 10% of the cases, significant growth disturbance may occur. Bioresorbable Magnesium-based implants represent a strategy to minimize damage (i.e., load support until bone healing without second surgery). Nevertheless, the absence of harmful effects of magnesium-implants and their degradation products on the growth plate should be confirmed. Here, the proteome of human mesenchymal stem cells undergoing chondrogenesis was evaluated when exposed to the products of various Magnesium-based materials degradation. The results of this study indicate that the materials induced regulation of proteins associated with cell chondrogenesis and cartilage formation, which should be beneficial for cartilage regeneration.

AB - Treatment of physeal fractures (15%-30% of all paediatric fractures) remains a challenge as in approximately 10% of the cases, significant growth disturbance may occur. Bioresorbable Magnesium-based implants represent a strategy to minimize damage (i.e., load support until bone healing without second surgery). Nevertheless, the absence of harmful effects of magnesium-implants and their degradation products on the growth plate should be confirmed. Here, the proteome of human mesenchymal stem cells undergoing chondrogenesis was evaluated when exposed to the products of various Magnesium-based materials degradation. The results of this study indicate that the materials induced regulation of proteins associated with cell chondrogenesis and cartilage formation, which should be beneficial for cartilage regeneration.

KW - Journal Article

U2 - 10.1016/j.bioactmat.2019.04.001

DO - 10.1016/j.bioactmat.2019.04.001

M3 - SCORING: Journal article

C2 - 31049466

VL - 4

SP - 168

EP - 188

JO - BIOACT MATER

JF - BIOACT MATER

SN - 2452-199X

ER -