Protein tyrosine phosphatase non-receptor type 22 (PTPN22) gene polymorphisms in liver transplant donors and impact on acute cellular liver transplant rejection

Hansjörg Thude; Petra Tiede; Matthias Marget; Sven Peine; Björn Nashan; Martina Koch

doi:10.1111/tan.13706

Protein tyrosine phosphatase non-receptor type 22 (PTPN22) gene polymorphisms in liver transplant donors and impact on acute cellular liver transplant rejection

Standard

Protein tyrosine phosphatase non-receptor type 22 (PTPN22) gene polymorphisms in liver transplant donors and impact on acute cellular liver transplant rejection. / Thude, Hansjörg; Tiede, Petra; Marget, Matthias ; Peine, Sven; Nashan, Björn; Koch, Martina.

in: HLA, Jahrgang 95, Nr. 1, 01.2020, S. 40-44.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Thude, H, Tiede, P, Marget, M , Peine, S, Nashan, B & Koch, M 2020, 'Protein tyrosine phosphatase non-receptor type 22 (PTPN22) gene polymorphisms in liver transplant donors and impact on acute cellular liver transplant rejection', HLA, Jg. 95, Nr. 1, S. 40-44. https://doi.org/10.1111/tan.13706

APA

Thude, H., Tiede, P., Marget, M., Peine, S., Nashan, B., & Koch, M. (2020). Protein tyrosine phosphatase non-receptor type 22 (PTPN22) gene polymorphisms in liver transplant donors and impact on acute cellular liver transplant rejection. HLA, 95(1), 40-44. https://doi.org/10.1111/tan.13706

Vancouver

Thude H, Tiede P, Marget M , Peine S, Nashan B, Koch M. Protein tyrosine phosphatase non-receptor type 22 (PTPN22) gene polymorphisms in liver transplant donors and impact on acute cellular liver transplant rejection. HLA. 2020 Jan;95(1):40-44. https://doi.org/10.1111/tan.13706

Bibtex

@article{0318c23f12934745a8b2c508b83fa45e,

title = "Protein tyrosine phosphatase non-receptor type 22 (PTPN22) gene polymorphisms in liver transplant donors and impact on acute cellular liver transplant rejection",

abstract = "The PTPN22 gene encodes the lymphoid protein tyrosine phosphatase involved in regulation the immune response. The single nucleotide polymorphisms (SNPs) rs1217388, rs1310182, rs2476601, and rs2488457 are located within the PTPN22 gene. We investigated whether these SNPs in liver transplant donors are associated with acute cellular rejection in the recipients. The SNPs were analyzed in donors (n = 104) of recipients who did not develop an acute cellular rejection and in donors (n = 53) of corresponding recipients developing an acute cellular rejection. No significant differences in genotype and allele frequencies of these SNPs were detected in either of the group. Our data suggest that these SNPs in liver transplant donors have no impact on the susceptibility of acute cellular liver transplant rejection.",

author = "Hansj{\"o}rg Thude and Petra Tiede and Matthias Marget and Sven Peine and Bj{\"o}rn Nashan and Martina Koch",

note = "{\textcopyright} 2019 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.",

year = "2020",

month = jan,

doi = "10.1111/tan.13706",

language = "English",

volume = "95",

pages = "40--44",

journal = "HLA",

issn = "2059-2302",

publisher = "Wiley-Blackwell",

number = "1",

}

RIS

TY - JOUR

T1 - Protein tyrosine phosphatase non-receptor type 22 (PTPN22) gene polymorphisms in liver transplant donors and impact on acute cellular liver transplant rejection

AU - Thude, Hansjörg

AU - Tiede, Petra

AU - Marget, Matthias

AU - Peine, Sven

AU - Nashan, Björn

AU - Koch, Martina

PY - 2020/1

Y1 - 2020/1

N2 - The PTPN22 gene encodes the lymphoid protein tyrosine phosphatase involved in regulation the immune response. The single nucleotide polymorphisms (SNPs) rs1217388, rs1310182, rs2476601, and rs2488457 are located within the PTPN22 gene. We investigated whether these SNPs in liver transplant donors are associated with acute cellular rejection in the recipients. The SNPs were analyzed in donors (n = 104) of recipients who did not develop an acute cellular rejection and in donors (n = 53) of corresponding recipients developing an acute cellular rejection. No significant differences in genotype and allele frequencies of these SNPs were detected in either of the group. Our data suggest that these SNPs in liver transplant donors have no impact on the susceptibility of acute cellular liver transplant rejection.

AB - The PTPN22 gene encodes the lymphoid protein tyrosine phosphatase involved in regulation the immune response. The single nucleotide polymorphisms (SNPs) rs1217388, rs1310182, rs2476601, and rs2488457 are located within the PTPN22 gene. We investigated whether these SNPs in liver transplant donors are associated with acute cellular rejection in the recipients. The SNPs were analyzed in donors (n = 104) of recipients who did not develop an acute cellular rejection and in donors (n = 53) of corresponding recipients developing an acute cellular rejection. No significant differences in genotype and allele frequencies of these SNPs were detected in either of the group. Our data suggest that these SNPs in liver transplant donors have no impact on the susceptibility of acute cellular liver transplant rejection.

U2 - 10.1111/tan.13706

DO - 10.1111/tan.13706

M3 - SCORING: Journal article

C2 - 31577847

VL - 95

SP - 40

EP - 44

JO - HLA

JF - HLA

SN - 2059-2302

IS - 1

ER -