Prostate-Specific Membrane Antigen-Guided Surgery
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Prostate-Specific Membrane Antigen-Guided Surgery. / Maurer, Tobias; Graefen, Markus; van der Poel, Henk; Hamdy, Freddie; Briganti, Alberto; Eiber, Matthias; Wester, Hans-Jürgen; van Leeuwen, Fijs W B.
in: J NUCL MED, Jahrgang 61, Nr. 1, 01.2020, S. 6-12.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung
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TY - JOUR
T1 - Prostate-Specific Membrane Antigen-Guided Surgery
AU - Maurer, Tobias
AU - Graefen, Markus
AU - van der Poel, Henk
AU - Hamdy, Freddie
AU - Briganti, Alberto
AU - Eiber, Matthias
AU - Wester, Hans-Jürgen
AU - van Leeuwen, Fijs W B
N1 - © 2020 by the Society of Nuclear Medicine and Molecular Imaging.
PY - 2020/1
Y1 - 2020/1
N2 - Since its introduction to the diagnostic pathway for prostate cancer management, prostate-specific membrane antigen (PSMA)-ligand PET has demonstrated great potential. PSMA-ligand imaging is increasingly influencing therapeutic decision making, although its impact on patient outcomes still needs to be defined. One relatively new application, enabled through chemical and engineering efforts, is PSMA-guided surgery. This review highlights the potential of PSMA-guided surgery and discusses its implications in lymph node dissection in primary and recurrent prostate cancer.
AB - Since its introduction to the diagnostic pathway for prostate cancer management, prostate-specific membrane antigen (PSMA)-ligand PET has demonstrated great potential. PSMA-ligand imaging is increasingly influencing therapeutic decision making, although its impact on patient outcomes still needs to be defined. One relatively new application, enabled through chemical and engineering efforts, is PSMA-guided surgery. This review highlights the potential of PSMA-guided surgery and discusses its implications in lymph node dissection in primary and recurrent prostate cancer.
KW - Humans
KW - Ligands
KW - Lymph Node Excision
KW - Lymphatic Metastasis
KW - Male
KW - Medical Oncology/trends
KW - Neoplasm Recurrence, Local
KW - Positron-Emission Tomography
KW - Prostatic Neoplasms/immunology
KW - Proteasome Endopeptidase Complex/analysis
KW - Radiopharmaceuticals
KW - Radiosurgery
KW - Salvage Therapy
KW - Surgery, Computer-Assisted
KW - Technetium/chemistry
KW - Urology/trends
U2 - 10.2967/jnumed.119.232330
DO - 10.2967/jnumed.119.232330
M3 - SCORING: Review article
C2 - 31732677
VL - 61
SP - 6
EP - 12
JO - J NUCL MED
JF - J NUCL MED
SN - 0161-5505
IS - 1
ER -