Prognostic value of intercellular adhesion molecule (ICAM)-1 expression in breast cancer.
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Prognostic value of intercellular adhesion molecule (ICAM)-1 expression in breast cancer. / Schröder, Christine; Witzel, Isabell; Müller, Volkmar; Krenkel, Sylke; Wirtz, Ralph M; Jänicke, Fritz; Schumacher, Udo; Milde-Langosch, Karin.
in: J CANCER RES CLIN, Jahrgang 137, Nr. 8, 8, 2011, S. 1193-1201.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Prognostic value of intercellular adhesion molecule (ICAM)-1 expression in breast cancer.
AU - Schröder, Christine
AU - Witzel, Isabell
AU - Müller, Volkmar
AU - Krenkel, Sylke
AU - Wirtz, Ralph M
AU - Jänicke, Fritz
AU - Schumacher, Udo
AU - Milde-Langosch, Karin
PY - 2011
Y1 - 2011
N2 - The intercellular adhesion molecule (ICAM)-1 is expressed on many cell types including endothelial cells and different cancer cell entities. Experimental data strongly indicate that ICAM-1 can activate intracellular signalling pathways in cancer cells leading to enhanced cell motility, invasion and metastasis. Yet, little is known about the role of ICAM-1 expression during malignant progression in breast cancer patients.
AB - The intercellular adhesion molecule (ICAM)-1 is expressed on many cell types including endothelial cells and different cancer cell entities. Experimental data strongly indicate that ICAM-1 can activate intracellular signalling pathways in cancer cells leading to enhanced cell motility, invasion and metastasis. Yet, little is known about the role of ICAM-1 expression during malignant progression in breast cancer patients.
KW - Adult
KW - Humans
KW - Aged
KW - Female
KW - Middle Aged
KW - Aged, 80 and over
KW - Treatment Outcome
KW - Immunohistochemistry
KW - Lymphatic Metastasis
KW - Predictive Value of Tests
KW - Prognosis
KW - Disease-Free Survival
KW - Up-Regulation
KW - Gene Expression Regulation, Neoplastic
KW - Neoplasm Staging
KW - Enzyme-Linked Immunosorbent Assay
KW - Blotting, Western
KW - Receptors, Estrogen/analysis
KW - Breast Neoplasms/blood/chemistry/mortality/pathology/therapy
KW - Carcinoma, Ductal, Breast/chemistry/pathology
KW - Carcinoma, Lobular/chemistry/pathology
KW - Intercellular Adhesion Molecule-1/chemistry/genetics
KW - Ki-67 Antigen/analysis
KW - Plasminogen Activator Inhibitor 1/analysis
KW - Protein Array Analysis/methods
KW - RNA, Messenger/analysis
KW - Receptors, Progesterone/analysis
KW - Tumor Markers, Biological/chemistry/genetics
KW - Urokinase-Type Plasminogen Activator/analysis
KW - Vascular Endothelial Growth Factor A/analysis
KW - Adult
KW - Humans
KW - Aged
KW - Female
KW - Middle Aged
KW - Aged, 80 and over
KW - Treatment Outcome
KW - Immunohistochemistry
KW - Lymphatic Metastasis
KW - Predictive Value of Tests
KW - Prognosis
KW - Disease-Free Survival
KW - Up-Regulation
KW - Gene Expression Regulation, Neoplastic
KW - Neoplasm Staging
KW - Enzyme-Linked Immunosorbent Assay
KW - Blotting, Western
KW - Receptors, Estrogen/analysis
KW - Breast Neoplasms/blood/chemistry/mortality/pathology/therapy
KW - Carcinoma, Ductal, Breast/chemistry/pathology
KW - Carcinoma, Lobular/chemistry/pathology
KW - Intercellular Adhesion Molecule-1/chemistry/genetics
KW - Ki-67 Antigen/analysis
KW - Plasminogen Activator Inhibitor 1/analysis
KW - Protein Array Analysis/methods
KW - RNA, Messenger/analysis
KW - Receptors, Progesterone/analysis
KW - Tumor Markers, Biological/chemistry/genetics
KW - Urokinase-Type Plasminogen Activator/analysis
KW - Vascular Endothelial Growth Factor A/analysis
M3 - SCORING: Journal article
VL - 137
SP - 1193
EP - 1201
JO - J CANCER RES CLIN
JF - J CANCER RES CLIN
SN - 0171-5216
IS - 8
M1 - 8
ER -