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Prognostic role of subsequent atrial tachycardias occurring during ablation of persistent atrial fibrillation: a prospective randomized trial

Standard

Prognostic role of subsequent atrial tachycardias occurring during ablation of persistent atrial fibrillation: a prospective randomized trial. / Rostock, Thomas; Salukhe, Tushar V; Hoffmann, Boris A; Steven, Daniel; Berner, Imke; Müllerleile, Kai; Theis, Cathrin; Bock, Karsten; Servatius, Helge; Sultan, Arian; Willems, Stephan.

in: CIRC-ARRHYTHMIA ELEC, Jahrgang 6, Nr. 6, 12.2013, S. 1059-1065.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Rostock, T, Salukhe, TV, Hoffmann, BA, Steven, D, Berner, I, Müllerleile, K, Theis, C, Bock, K, Servatius, H, Sultan, A & Willems, S 2013, 'Prognostic role of subsequent atrial tachycardias occurring during ablation of persistent atrial fibrillation: a prospective randomized trial', CIRC-ARRHYTHMIA ELEC, Jg. 6, Nr. 6, S. 1059-1065. https://doi.org/10.1161/CIRCEP.113.001019

APA

Rostock, T., Salukhe, T. V., Hoffmann, B. A., Steven, D., Berner, I., Müllerleile, K., Theis, C., Bock, K., Servatius, H., Sultan, A., & Willems, S. (2013). Prognostic role of subsequent atrial tachycardias occurring during ablation of persistent atrial fibrillation: a prospective randomized trial. CIRC-ARRHYTHMIA ELEC, 6(6), 1059-1065. https://doi.org/10.1161/CIRCEP.113.001019

Vancouver

Rostock T, Salukhe TV, Hoffmann BA, Steven D, Berner I, Müllerleile K et al. Prognostic role of subsequent atrial tachycardias occurring during ablation of persistent atrial fibrillation: a prospective randomized trial. CIRC-ARRHYTHMIA ELEC. 2013 Dez;6(6):1059-1065. https://doi.org/10.1161/CIRCEP.113.001019

Bibtex

@article{a0dd7c138194427ba0992208f703c6d8,
title = "Prognostic role of subsequent atrial tachycardias occurring during ablation of persistent atrial fibrillation: a prospective randomized trial",
abstract = "BACKGROUND: The role of subsequent atrial tachycardias (AT) in the context of persistent atrial fibrillation (AF) remains undetermined. This study evaluated the prognostic role of subsequent ATs for arrhythmia recurrences after catheter ablation of persistent AF.METHODS AND RESULTS: A total of 110 patients with persistent AF (63±9 years; 22 women; 61 long-lasting persistent AF) underwent pulmonary vein isolation followed by electrogram-guided ablation. After AF terminated to AT, patients were separated by the randomization protocol to receive either direct cardioversion (group A) or further ablation of subsequent ATs to sinus rhythm (group B). After a mean follow-up of 20.1±13.3 months after the first procedure, significantly more group B patients were in sinus rhythm as compared with patients in group A (30 [57%] versus 18 [34%]; P=0.02). Moreover, recurrences of AF were significantly less frequent of group B than in group A patients (10 [19%] versus 26 [49%]; P=0.001). After the last procedure (follow-up, 34.0±6.4 months), significantly more group B patients were free of AF as compared with patients of group A (49 [92%] versus 39 [74%]; P=0.01). The proportion of AT recurrences did not differ between the 2 groups after the first and final procedures. The strongest predictor for an arrhythmia-free survival after a single procedure was randomization to the procedural end point of termination to sinus rhythm by elimination of subsequent ATs (P=0.004).CONCLUSIONS: Catheter ablation of subsequent ATs increases freedom from AF but not AT, suggesting a contributing role of subsequent ATs in the mechanisms of persistent AF.CLINICAL TRIAL REGISTRATION: URL: http://www.clinicaltrials.gov. Unique identifier: NCT01896570.",
keywords = "Aged, Atrial Fibrillation/complications, Catheter Ablation, Electric Countershock, Female, Humans, Kaplan-Meier Estimate, Male, Middle Aged, Prognosis, Prospective Studies, Tachycardia, Ectopic Atrial/complications",
author = "Thomas Rostock and Salukhe, {Tushar V} and Hoffmann, {Boris A} and Daniel Steven and Imke Berner and Kai M{\"u}llerleile and Cathrin Theis and Karsten Bock and Helge Servatius and Arian Sultan and Stephan Willems",
year = "2013",
month = dec,
doi = "10.1161/CIRCEP.113.001019",
language = "English",
volume = "6",
pages = "1059--1065",
journal = "CIRC-ARRHYTHMIA ELEC",
issn = "1941-3149",
publisher = "Lippincott Williams and Wilkins",
number = "6",

}

RIS

TY - JOUR

T1 - Prognostic role of subsequent atrial tachycardias occurring during ablation of persistent atrial fibrillation: a prospective randomized trial

AU - Rostock, Thomas

AU - Salukhe, Tushar V

AU - Hoffmann, Boris A

AU - Steven, Daniel

AU - Berner, Imke

AU - Müllerleile, Kai

AU - Theis, Cathrin

AU - Bock, Karsten

AU - Servatius, Helge

AU - Sultan, Arian

AU - Willems, Stephan

PY - 2013/12

Y1 - 2013/12

N2 - BACKGROUND: The role of subsequent atrial tachycardias (AT) in the context of persistent atrial fibrillation (AF) remains undetermined. This study evaluated the prognostic role of subsequent ATs for arrhythmia recurrences after catheter ablation of persistent AF.METHODS AND RESULTS: A total of 110 patients with persistent AF (63±9 years; 22 women; 61 long-lasting persistent AF) underwent pulmonary vein isolation followed by electrogram-guided ablation. After AF terminated to AT, patients were separated by the randomization protocol to receive either direct cardioversion (group A) or further ablation of subsequent ATs to sinus rhythm (group B). After a mean follow-up of 20.1±13.3 months after the first procedure, significantly more group B patients were in sinus rhythm as compared with patients in group A (30 [57%] versus 18 [34%]; P=0.02). Moreover, recurrences of AF were significantly less frequent of group B than in group A patients (10 [19%] versus 26 [49%]; P=0.001). After the last procedure (follow-up, 34.0±6.4 months), significantly more group B patients were free of AF as compared with patients of group A (49 [92%] versus 39 [74%]; P=0.01). The proportion of AT recurrences did not differ between the 2 groups after the first and final procedures. The strongest predictor for an arrhythmia-free survival after a single procedure was randomization to the procedural end point of termination to sinus rhythm by elimination of subsequent ATs (P=0.004).CONCLUSIONS: Catheter ablation of subsequent ATs increases freedom from AF but not AT, suggesting a contributing role of subsequent ATs in the mechanisms of persistent AF.CLINICAL TRIAL REGISTRATION: URL: http://www.clinicaltrials.gov. Unique identifier: NCT01896570.

AB - BACKGROUND: The role of subsequent atrial tachycardias (AT) in the context of persistent atrial fibrillation (AF) remains undetermined. This study evaluated the prognostic role of subsequent ATs for arrhythmia recurrences after catheter ablation of persistent AF.METHODS AND RESULTS: A total of 110 patients with persistent AF (63±9 years; 22 women; 61 long-lasting persistent AF) underwent pulmonary vein isolation followed by electrogram-guided ablation. After AF terminated to AT, patients were separated by the randomization protocol to receive either direct cardioversion (group A) or further ablation of subsequent ATs to sinus rhythm (group B). After a mean follow-up of 20.1±13.3 months after the first procedure, significantly more group B patients were in sinus rhythm as compared with patients in group A (30 [57%] versus 18 [34%]; P=0.02). Moreover, recurrences of AF were significantly less frequent of group B than in group A patients (10 [19%] versus 26 [49%]; P=0.001). After the last procedure (follow-up, 34.0±6.4 months), significantly more group B patients were free of AF as compared with patients of group A (49 [92%] versus 39 [74%]; P=0.01). The proportion of AT recurrences did not differ between the 2 groups after the first and final procedures. The strongest predictor for an arrhythmia-free survival after a single procedure was randomization to the procedural end point of termination to sinus rhythm by elimination of subsequent ATs (P=0.004).CONCLUSIONS: Catheter ablation of subsequent ATs increases freedom from AF but not AT, suggesting a contributing role of subsequent ATs in the mechanisms of persistent AF.CLINICAL TRIAL REGISTRATION: URL: http://www.clinicaltrials.gov. Unique identifier: NCT01896570.

KW - Aged

KW - Atrial Fibrillation/complications

KW - Catheter Ablation

KW - Electric Countershock

KW - Female

KW - Humans

KW - Kaplan-Meier Estimate

KW - Male

KW - Middle Aged

KW - Prognosis

KW - Prospective Studies

KW - Tachycardia, Ectopic Atrial/complications

U2 - 10.1161/CIRCEP.113.001019

DO - 10.1161/CIRCEP.113.001019

M3 - SCORING: Journal article

C2 - 24162833

VL - 6

SP - 1059

EP - 1065

JO - CIRC-ARRHYTHMIA ELEC

JF - CIRC-ARRHYTHMIA ELEC

SN - 1941-3149

IS - 6

ER -