Prognostic relevance of Bcl-2 overexpression in surgically treated prostate cancer is not caused by increased copy number or translocation of the gene.

Standard

Prognostic relevance of Bcl-2 overexpression in surgically treated prostate cancer is not caused by increased copy number or translocation of the gene. / Fleischmann, A; Huland, Hartwig; Mirlacher, Martina; Wilczak, Waldemar; Simon, Ronald; Erbersdobler, Andreas; Sauter, G; Schlomm, Thorsten.

in: PROSTATE, Jahrgang 72, Nr. 9, 9, 2012, S. 991-997.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

Harvard

APA

Vancouver

Bibtex

@article{12b3c56c506543d084c6d13069fd8233,
title = "Prognostic relevance of Bcl-2 overexpression in surgically treated prostate cancer is not caused by increased copy number or translocation of the gene.",
abstract = "Overexpression of anti-apoptotic Bcl-2 plays a role in prostate cancer progression, particularly in transformation to androgen-independent disease. Androgen-independent prostate cancers have been shown to harbor Bcl-2 gene copy number gains frequently suggesting that this genetic alteration might play a role in Bcl-2 overexpression. The relation of Bcl-2 overexpression and copy number gains or translocation of the BCL-2 gene in prostate cancer under hormone-na{\"i}ve conditions is unknown.",
author = "A Fleischmann and Hartwig Huland and Martina Mirlacher and Waldemar Wilczak and Ronald Simon and Andreas Erbersdobler and G Sauter and Thorsten Schlomm",
year = "2012",
language = "English",
volume = "72",
pages = "991--997",
journal = "PROSTATE",
issn = "0270-4137",
publisher = "Wiley-Liss Inc.",
number = "9",

}

RIS

TY - JOUR

T1 - Prognostic relevance of Bcl-2 overexpression in surgically treated prostate cancer is not caused by increased copy number or translocation of the gene.

AU - Fleischmann, A

AU - Huland, Hartwig

AU - Mirlacher, Martina

AU - Wilczak, Waldemar

AU - Simon, Ronald

AU - Erbersdobler, Andreas

AU - Sauter, G

AU - Schlomm, Thorsten

PY - 2012

Y1 - 2012

N2 - Overexpression of anti-apoptotic Bcl-2 plays a role in prostate cancer progression, particularly in transformation to androgen-independent disease. Androgen-independent prostate cancers have been shown to harbor Bcl-2 gene copy number gains frequently suggesting that this genetic alteration might play a role in Bcl-2 overexpression. The relation of Bcl-2 overexpression and copy number gains or translocation of the BCL-2 gene in prostate cancer under hormone-naïve conditions is unknown.

AB - Overexpression of anti-apoptotic Bcl-2 plays a role in prostate cancer progression, particularly in transformation to androgen-independent disease. Androgen-independent prostate cancers have been shown to harbor Bcl-2 gene copy number gains frequently suggesting that this genetic alteration might play a role in Bcl-2 overexpression. The relation of Bcl-2 overexpression and copy number gains or translocation of the BCL-2 gene in prostate cancer under hormone-naïve conditions is unknown.

M3 - SCORING: Journal article

VL - 72

SP - 991

EP - 997

JO - PROSTATE

JF - PROSTATE

SN - 0270-4137

IS - 9

M1 - 9

ER -