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Prognosis and treatment of primary deep soft tissue sarcomas.

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Prognosis and treatment of primary deep soft tissue sarcomas. / Alldinger, Ingo; Yang, Qin; Gocht, Andreas; Raffel, Andreas; Knoefel, Wolfram T; Peiper, Matthias.

in: ANTICANCER RES, Jahrgang 27, Nr. 4, 4, 2007, S. 2759-2764.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Alldinger, I, Yang, Q, Gocht, A, Raffel, A, Knoefel, WT & Peiper, M 2007, 'Prognosis and treatment of primary deep soft tissue sarcomas.', ANTICANCER RES, Jg. 27, Nr. 4, 4, S. 2759-2764. <http://www.ncbi.nlm.nih.gov/pubmed/17695444?dopt=Citation>

APA

Alldinger, I., Yang, Q., Gocht, A., Raffel, A., Knoefel, W. T., & Peiper, M. (2007). Prognosis and treatment of primary deep soft tissue sarcomas. ANTICANCER RES, 27(4), 2759-2764. [4]. http://www.ncbi.nlm.nih.gov/pubmed/17695444?dopt=Citation

Vancouver

Alldinger I, Yang Q, Gocht A, Raffel A, Knoefel WT, Peiper M. Prognosis and treatment of primary deep soft tissue sarcomas. ANTICANCER RES. 2007;27(4):2759-2764. 4.

Bibtex

@article{c4521227185e49e9bc463bb65ebdce56,
title = "Prognosis and treatment of primary deep soft tissue sarcomas.",
abstract = "The objective of this study was to define the prognostic factors for survival of patients with soft tissue sarcomas (STS) of the extremities located below the muscular fascia. PATIENTS AND METHODS: One hundred and twenty-seven consecutive patients, resected in our Institution between March 1988 and December 2002, were reviewed. RESULTS: On univariate analysis, the prognostic factors for survival were tumor size, nodal status, adequate surgery, tumor malignancy grade and administered chemotherapy. Additionally, local failure, metastasis after resection and residual tumor after incomplete resection followed by complete resection were adverse prognostic factors for survival. The tumor size, nodal status and metastasis after resection were factors indicating worse survival on multivariate analysis. CONCLUSION: Our results indicate that most factors influencing the course of the disease cannot be controlled by the surgeon. Complete resection is imperative for local control and allows the patient the chance of a cure. New treatment procedures should be evaluated in prospective trials to optimize therapy. Surgery without sufficient information on the malignancy or expansion of the tumor might be detrimental for the patient.",
author = "Ingo Alldinger and Qin Yang and Andreas Gocht and Andreas Raffel and Knoefel, {Wolfram T} and Matthias Peiper",
year = "2007",
language = "Deutsch",
volume = "27",
pages = "2759--2764",
journal = "ANTICANCER RES",
issn = "0250-7005",
publisher = "International Institute of Anticancer Research",
number = "4",

}

RIS

TY - JOUR

T1 - Prognosis and treatment of primary deep soft tissue sarcomas.

AU - Alldinger, Ingo

AU - Yang, Qin

AU - Gocht, Andreas

AU - Raffel, Andreas

AU - Knoefel, Wolfram T

AU - Peiper, Matthias

PY - 2007

Y1 - 2007

N2 - The objective of this study was to define the prognostic factors for survival of patients with soft tissue sarcomas (STS) of the extremities located below the muscular fascia. PATIENTS AND METHODS: One hundred and twenty-seven consecutive patients, resected in our Institution between March 1988 and December 2002, were reviewed. RESULTS: On univariate analysis, the prognostic factors for survival were tumor size, nodal status, adequate surgery, tumor malignancy grade and administered chemotherapy. Additionally, local failure, metastasis after resection and residual tumor after incomplete resection followed by complete resection were adverse prognostic factors for survival. The tumor size, nodal status and metastasis after resection were factors indicating worse survival on multivariate analysis. CONCLUSION: Our results indicate that most factors influencing the course of the disease cannot be controlled by the surgeon. Complete resection is imperative for local control and allows the patient the chance of a cure. New treatment procedures should be evaluated in prospective trials to optimize therapy. Surgery without sufficient information on the malignancy or expansion of the tumor might be detrimental for the patient.

AB - The objective of this study was to define the prognostic factors for survival of patients with soft tissue sarcomas (STS) of the extremities located below the muscular fascia. PATIENTS AND METHODS: One hundred and twenty-seven consecutive patients, resected in our Institution between March 1988 and December 2002, were reviewed. RESULTS: On univariate analysis, the prognostic factors for survival were tumor size, nodal status, adequate surgery, tumor malignancy grade and administered chemotherapy. Additionally, local failure, metastasis after resection and residual tumor after incomplete resection followed by complete resection were adverse prognostic factors for survival. The tumor size, nodal status and metastasis after resection were factors indicating worse survival on multivariate analysis. CONCLUSION: Our results indicate that most factors influencing the course of the disease cannot be controlled by the surgeon. Complete resection is imperative for local control and allows the patient the chance of a cure. New treatment procedures should be evaluated in prospective trials to optimize therapy. Surgery without sufficient information on the malignancy or expansion of the tumor might be detrimental for the patient.

M3 - SCORING: Zeitschriftenaufsatz

VL - 27

SP - 2759

EP - 2764

JO - ANTICANCER RES

JF - ANTICANCER RES

SN - 0250-7005

IS - 4

M1 - 4

ER -