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Primary Bone Tumors of the Spine-Proposal for Treatment Based on a Single Centre Experience

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Primary Bone Tumors of the Spine-Proposal for Treatment Based on a Single Centre Experience. / Lange, Nicole; Jörger, Ann-Kathrin; Ryang, Yu-Mi; Liesche-Starnecker, Friederike; Gempt, Jens; Meyer, Bernhard.

in: DIAGNOSTICS, Jahrgang 12, Nr. 9, 2264, 19.09.2022.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Lange, N, Jörger, A-K, Ryang, Y-M, Liesche-Starnecker, F, Gempt, J & Meyer, B 2022, 'Primary Bone Tumors of the Spine-Proposal for Treatment Based on a Single Centre Experience', DIAGNOSTICS, Jg. 12, Nr. 9, 2264. https://doi.org/10.3390/diagnostics12092264

APA

Lange, N., Jörger, A-K., Ryang, Y-M., Liesche-Starnecker, F., Gempt, J., & Meyer, B. (2022). Primary Bone Tumors of the Spine-Proposal for Treatment Based on a Single Centre Experience. DIAGNOSTICS, 12(9), [2264]. https://doi.org/10.3390/diagnostics12092264

Vancouver

Lange N, Jörger A-K, Ryang Y-M, Liesche-Starnecker F, Gempt J, Meyer B. Primary Bone Tumors of the Spine-Proposal for Treatment Based on a Single Centre Experience. DIAGNOSTICS. 2022 Sep 19;12(9). 2264. https://doi.org/10.3390/diagnostics12092264

Bibtex

@article{ad1102ea4d35470e802a021d10177bef,
title = "Primary Bone Tumors of the Spine-Proposal for Treatment Based on a Single Centre Experience",
abstract = "This study reports a large single-center series of primary bone tumors of the spine (PBTs). We aimed to review the concepts for management, as this kind of tumor represents a very rare entity, and also propose a new treatment algorithm. Retrospective analysis revealed 92 patients receiving surgery for PBTs from 2007 to 2019 at our center. They were analyzed based on surgical management and the course of the disease. A total of 145 surgical procedures were performed (50 cervical, 46 thoracic, 28 lumbar, and 21 sacral). Complete tumor resection was achieved in 65%, of which 22% showed tumor recurrence during follow-up (mean time to recurrence 334 days). The five-year mortality rate was significantly lower after complete resection (3% versus 25% after subtotal resection). Most of the patients improved in their symptoms through surgery. Regarding the tumor entity, the most common PBTs were vertebral hemangiomas (20%), osteoid osteomas (15%), and chordomas (16%). The Enneking graduation system showed a good correlation with the risk of recurrence and mortality. Complete resection in PBTs increased survival rates and remains the method of choice. Thus, quality of life-especially with a higher extent of resection-should be considered.",
author = "Nicole Lange and Ann-Kathrin J{\"o}rger and Yu-Mi Ryang and Friederike Liesche-Starnecker and Jens Gempt and Bernhard Meyer",
year = "2022",
month = sep,
day = "19",
doi = "10.3390/diagnostics12092264",
language = "English",
volume = "12",
journal = "DIAGNOSTICS",
issn = "2075-4418",
publisher = "MDPI AG",
number = "9",

}

RIS

TY - JOUR

T1 - Primary Bone Tumors of the Spine-Proposal for Treatment Based on a Single Centre Experience

AU - Lange, Nicole

AU - Jörger, Ann-Kathrin

AU - Ryang, Yu-Mi

AU - Liesche-Starnecker, Friederike

AU - Gempt, Jens

AU - Meyer, Bernhard

PY - 2022/9/19

Y1 - 2022/9/19

N2 - This study reports a large single-center series of primary bone tumors of the spine (PBTs). We aimed to review the concepts for management, as this kind of tumor represents a very rare entity, and also propose a new treatment algorithm. Retrospective analysis revealed 92 patients receiving surgery for PBTs from 2007 to 2019 at our center. They were analyzed based on surgical management and the course of the disease. A total of 145 surgical procedures were performed (50 cervical, 46 thoracic, 28 lumbar, and 21 sacral). Complete tumor resection was achieved in 65%, of which 22% showed tumor recurrence during follow-up (mean time to recurrence 334 days). The five-year mortality rate was significantly lower after complete resection (3% versus 25% after subtotal resection). Most of the patients improved in their symptoms through surgery. Regarding the tumor entity, the most common PBTs were vertebral hemangiomas (20%), osteoid osteomas (15%), and chordomas (16%). The Enneking graduation system showed a good correlation with the risk of recurrence and mortality. Complete resection in PBTs increased survival rates and remains the method of choice. Thus, quality of life-especially with a higher extent of resection-should be considered.

AB - This study reports a large single-center series of primary bone tumors of the spine (PBTs). We aimed to review the concepts for management, as this kind of tumor represents a very rare entity, and also propose a new treatment algorithm. Retrospective analysis revealed 92 patients receiving surgery for PBTs from 2007 to 2019 at our center. They were analyzed based on surgical management and the course of the disease. A total of 145 surgical procedures were performed (50 cervical, 46 thoracic, 28 lumbar, and 21 sacral). Complete tumor resection was achieved in 65%, of which 22% showed tumor recurrence during follow-up (mean time to recurrence 334 days). The five-year mortality rate was significantly lower after complete resection (3% versus 25% after subtotal resection). Most of the patients improved in their symptoms through surgery. Regarding the tumor entity, the most common PBTs were vertebral hemangiomas (20%), osteoid osteomas (15%), and chordomas (16%). The Enneking graduation system showed a good correlation with the risk of recurrence and mortality. Complete resection in PBTs increased survival rates and remains the method of choice. Thus, quality of life-especially with a higher extent of resection-should be considered.

U2 - 10.3390/diagnostics12092264

DO - 10.3390/diagnostics12092264

M3 - SCORING: Journal article

C2 - 36140664

VL - 12

JO - DIAGNOSTICS

JF - DIAGNOSTICS

SN - 2075-4418

IS - 9

M1 - 2264

ER -