PREPARE trial: a randomized phase III trial comparing preoperative, dose-dense, dose-intensified chemotherapy with epirubicin, paclitaxel and CMF versus a standard-dosed epirubicin/cyclophosphamide followed by paclitaxel ± darbepoetin alfa in primary breast cancer--results at the time of surgery.

  • M Untch
  • P A Fasching
  • G E Konecny
  • F von Koch
  • U Conrad
  • W Fett
  • C Kurzeder
  • H-J Lück
  • E Stickeler
  • H Urbaczyk
  • B Liedtke
  • C Salat
  • N Harbeck
  • Volkmar Müller
  • M Schmidt
  • S Hasmüller
  • M Lenhard
  • T Schuster
  • V Nekljudova
  • Annette Lebeau
  • S Loibl
  • G von Minckwitz
  • Arbeitsgemeinschaft Gynäkologische Onkologie PREPARE Investigators

Abstract

Preoperative chemotherapy is a recommended treatment of both primary operable and locally advanced breast cancer. Strategies to improve efficacy include the use of anthracyclines, taxanes, and intensified dose with bone marrow support.

Bibliografische Daten

OriginalspracheEnglisch
Aufsatznummer9
ISSN0923-7534
StatusVeröffentlicht - 2011
pubmed 21385882