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Prediction of malignant middle cerebral artery infarction by early perfusion- and diffusion-weighted magnetic resonance imaging.

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Prediction of malignant middle cerebral artery infarction by early perfusion- and diffusion-weighted magnetic resonance imaging. / Thomalla, Götz; Kucinski, Thomas; Schoder, Volker; Fiehler, Jens; Knab, Rene; Zeumer, Hermann; Weiller, Cornelius; Röther, Joachim.

in: STROKE, Jahrgang 34, Nr. 8, 8, 2003, S. 1892-1899.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Thomalla, G, Kucinski, T, Schoder, V, Fiehler, J, Knab, R, Zeumer, H, Weiller, C & Röther, J 2003, 'Prediction of malignant middle cerebral artery infarction by early perfusion- and diffusion-weighted magnetic resonance imaging.', STROKE, Jg. 34, Nr. 8, 8, S. 1892-1899. <http://www.ncbi.nlm.nih.gov/pubmed/12855829?dopt=Citation>

APA

Thomalla, G., Kucinski, T., Schoder, V., Fiehler, J., Knab, R., Zeumer, H., Weiller, C., & Röther, J. (2003). Prediction of malignant middle cerebral artery infarction by early perfusion- and diffusion-weighted magnetic resonance imaging. STROKE, 34(8), 1892-1899. [8]. http://www.ncbi.nlm.nih.gov/pubmed/12855829?dopt=Citation

Vancouver

Thomalla G, Kucinski T, Schoder V, Fiehler J, Knab R, Zeumer H et al. Prediction of malignant middle cerebral artery infarction by early perfusion- and diffusion-weighted magnetic resonance imaging. STROKE. 2003;34(8):1892-1899. 8.

Bibtex

@article{19145faa76864ffebc5577090c86aefa,
title = "Prediction of malignant middle cerebral artery infarction by early perfusion- and diffusion-weighted magnetic resonance imaging.",
abstract = "BACKGROUND AND PURPOSE: We tested the hypothesis that early diffusion- and perfusion-weighted MRI (DWI and PWI, respectively) allows the prediction of malignant middle cerebral artery (MCA) infarction (MMI). METHODS: Thirty-seven patients with acute MCA infarction and proximal vessel occlusion (carotid-T, MCA main stem) were studied by DWI, PWI, and MR angiography within 6 hours of symptom onset. Eleven patients developed MMI, defined by decline of consciousness and radiological signs of space-occupying brain edema. Lesion volumes were retrospectively defined as apparent diffusion coefficient +4 seconds (TTP>+4s) compared with the unaffected hemisphere. ADC decrease within the infarct core (ADCcore) and relative ADC within the ADC+4s (208 versus 125 mL; P82 mL, 87%, 91%; TTP>+4s >162 mL, 83%, 75%; TTP/ADC mismatch ratio or =19, 96%, 72%. CONCLUSIONS: Quantitative analysis of early DWI and PWI parameters allows the prediction of MMI and can help in the selection of patients for aggressive tissue-protective therapy.",
author = "G{\"o}tz Thomalla and Thomas Kucinski and Volker Schoder and Jens Fiehler and Rene Knab and Hermann Zeumer and Cornelius Weiller and Joachim R{\"o}ther",
year = "2003",
language = "Deutsch",
volume = "34",
pages = "1892--1899",
journal = "STROKE",
issn = "0039-2499",
publisher = "Lippincott Williams and Wilkins",
number = "8",

}

RIS

TY - JOUR

T1 - Prediction of malignant middle cerebral artery infarction by early perfusion- and diffusion-weighted magnetic resonance imaging.

AU - Thomalla, Götz

AU - Kucinski, Thomas

AU - Schoder, Volker

AU - Fiehler, Jens

AU - Knab, Rene

AU - Zeumer, Hermann

AU - Weiller, Cornelius

AU - Röther, Joachim

PY - 2003

Y1 - 2003

N2 - BACKGROUND AND PURPOSE: We tested the hypothesis that early diffusion- and perfusion-weighted MRI (DWI and PWI, respectively) allows the prediction of malignant middle cerebral artery (MCA) infarction (MMI). METHODS: Thirty-seven patients with acute MCA infarction and proximal vessel occlusion (carotid-T, MCA main stem) were studied by DWI, PWI, and MR angiography within 6 hours of symptom onset. Eleven patients developed MMI, defined by decline of consciousness and radiological signs of space-occupying brain edema. Lesion volumes were retrospectively defined as apparent diffusion coefficient +4 seconds (TTP>+4s) compared with the unaffected hemisphere. ADC decrease within the infarct core (ADCcore) and relative ADC within the ADC+4s (208 versus 125 mL; P82 mL, 87%, 91%; TTP>+4s >162 mL, 83%, 75%; TTP/ADC mismatch ratio or =19, 96%, 72%. CONCLUSIONS: Quantitative analysis of early DWI and PWI parameters allows the prediction of MMI and can help in the selection of patients for aggressive tissue-protective therapy.

AB - BACKGROUND AND PURPOSE: We tested the hypothesis that early diffusion- and perfusion-weighted MRI (DWI and PWI, respectively) allows the prediction of malignant middle cerebral artery (MCA) infarction (MMI). METHODS: Thirty-seven patients with acute MCA infarction and proximal vessel occlusion (carotid-T, MCA main stem) were studied by DWI, PWI, and MR angiography within 6 hours of symptom onset. Eleven patients developed MMI, defined by decline of consciousness and radiological signs of space-occupying brain edema. Lesion volumes were retrospectively defined as apparent diffusion coefficient +4 seconds (TTP>+4s) compared with the unaffected hemisphere. ADC decrease within the infarct core (ADCcore) and relative ADC within the ADC+4s (208 versus 125 mL; P82 mL, 87%, 91%; TTP>+4s >162 mL, 83%, 75%; TTP/ADC mismatch ratio or =19, 96%, 72%. CONCLUSIONS: Quantitative analysis of early DWI and PWI parameters allows the prediction of MMI and can help in the selection of patients for aggressive tissue-protective therapy.

M3 - SCORING: Zeitschriftenaufsatz

VL - 34

SP - 1892

EP - 1899

JO - STROKE

JF - STROKE

SN - 0039-2499

IS - 8

M1 - 8

ER -