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Prediction of dementia of Alzheimer type by different types of subjective cognitive decline

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Prediction of dementia of Alzheimer type by different types of subjective cognitive decline. / Jessen, Frank; Kleineidam, Luca; Wolfsgruber, Steffen; Bickel, Horst; Brettschneider, Christian; Fuchs, Angela; Kaduszkiewicz, Hanna; König, Hans-Helmut; Mallon, Tina; Mamone, Silke; Pabst, Alexander; Pentzek, Michael; Roehr, Susanne; Weeg, Dagmar; Jochen, Werle; Weyerer, Siegfried; Wiese, Birgitt; Maier, Wolfgang; Scherer, Martin; Riedel-Heller, Steffi; Wagner, Michael.

in: ALZHEIMERS DEMENT, Jahrgang 16, Nr. 12, 12.2020, S. 1745-1749.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Jessen, F, Kleineidam, L, Wolfsgruber, S, Bickel, H, Brettschneider, C, Fuchs, A, Kaduszkiewicz, H, König, H-H, Mallon, T, Mamone, S, Pabst, A, Pentzek, M, Roehr, S, Weeg, D, Jochen, W, Weyerer, S, Wiese, B, Maier, W, Scherer, M, Riedel-Heller, S & Wagner, M 2020, 'Prediction of dementia of Alzheimer type by different types of subjective cognitive decline', ALZHEIMERS DEMENT, Jg. 16, Nr. 12, S. 1745-1749. https://doi.org/10.1002/alz.12163

APA

Jessen, F., Kleineidam, L., Wolfsgruber, S., Bickel, H., Brettschneider, C., Fuchs, A., Kaduszkiewicz, H., König, H-H., Mallon, T., Mamone, S., Pabst, A., Pentzek, M., Roehr, S., Weeg, D., Jochen, W., Weyerer, S., Wiese, B., Maier, W., Scherer, M., ... Wagner, M. (2020). Prediction of dementia of Alzheimer type by different types of subjective cognitive decline. ALZHEIMERS DEMENT, 16(12), 1745-1749. https://doi.org/10.1002/alz.12163

Vancouver

Jessen F, Kleineidam L, Wolfsgruber S, Bickel H, Brettschneider C, Fuchs A et al. Prediction of dementia of Alzheimer type by different types of subjective cognitive decline. ALZHEIMERS DEMENT. 2020 Dez;16(12):1745-1749. https://doi.org/10.1002/alz.12163

Bibtex

@article{ecf8ae05546e46c9a2afc48289629056,
title = "Prediction of dementia of Alzheimer type by different types of subjective cognitive decline",
abstract = "INTRODUCTION: Subjective cognitive decline (SCD) is a risk condition for dementia, including dementia of Alzheimer type (DAT).METHODS: We report sensitivity, specificity, positive and negative predictive values (PPV, NPV) for conversion to all-cause dementia, and DAT in different SCD types (decline in memory, assocated worries, longitudinal consitency, of the AgeCoDe study (n = 2.402, 12 years follow-up).RESULTS: 82.7% of those converting to any dementia and 84.4% of those converting with DAT at follow-up, reported memory decline and fulfilled criteria of SCD at least at one time point before. SCD with worries at two consecutive time points showed a specificity of 92.2% for any dementia and also for DAT as well as a PPV of 44.3% for any dementia and of 36.9% for DAT at follow-up at the expense of low sensitivity.DISCUSSION: Different SCD subtypes were either sensitive or specific for future all-cause dementia and DAT in cognitively unimpaired individuals. Modest PPV of the most specific SCD subtypes were achieved in this low prevalence population.",
author = "Frank Jessen and Luca Kleineidam and Steffen Wolfsgruber and Horst Bickel and Christian Brettschneider and Angela Fuchs and Hanna Kaduszkiewicz and Hans-Helmut K{\"o}nig and Tina Mallon and Silke Mamone and Alexander Pabst and Michael Pentzek and Susanne Roehr and Dagmar Weeg and Werle Jochen and Siegfried Weyerer and Birgitt Wiese and Wolfgang Maier and Martin Scherer and Steffi Riedel-Heller and Michael Wagner",
note = "{\textcopyright} 2020 the Alzheimer's Association.",
year = "2020",
month = dec,
doi = "10.1002/alz.12163",
language = "English",
volume = "16",
pages = "1745--1749",
journal = "ALZHEIMERS DEMENT",
issn = "1552-5260",
publisher = "Elsevier Inc.",
number = "12",

}

RIS

TY - JOUR

T1 - Prediction of dementia of Alzheimer type by different types of subjective cognitive decline

AU - Jessen, Frank

AU - Kleineidam, Luca

AU - Wolfsgruber, Steffen

AU - Bickel, Horst

AU - Brettschneider, Christian

AU - Fuchs, Angela

AU - Kaduszkiewicz, Hanna

AU - König, Hans-Helmut

AU - Mallon, Tina

AU - Mamone, Silke

AU - Pabst, Alexander

AU - Pentzek, Michael

AU - Roehr, Susanne

AU - Weeg, Dagmar

AU - Jochen, Werle

AU - Weyerer, Siegfried

AU - Wiese, Birgitt

AU - Maier, Wolfgang

AU - Scherer, Martin

AU - Riedel-Heller, Steffi

AU - Wagner, Michael

N1 - © 2020 the Alzheimer's Association.

PY - 2020/12

Y1 - 2020/12

N2 - INTRODUCTION: Subjective cognitive decline (SCD) is a risk condition for dementia, including dementia of Alzheimer type (DAT).METHODS: We report sensitivity, specificity, positive and negative predictive values (PPV, NPV) for conversion to all-cause dementia, and DAT in different SCD types (decline in memory, assocated worries, longitudinal consitency, of the AgeCoDe study (n = 2.402, 12 years follow-up).RESULTS: 82.7% of those converting to any dementia and 84.4% of those converting with DAT at follow-up, reported memory decline and fulfilled criteria of SCD at least at one time point before. SCD with worries at two consecutive time points showed a specificity of 92.2% for any dementia and also for DAT as well as a PPV of 44.3% for any dementia and of 36.9% for DAT at follow-up at the expense of low sensitivity.DISCUSSION: Different SCD subtypes were either sensitive or specific for future all-cause dementia and DAT in cognitively unimpaired individuals. Modest PPV of the most specific SCD subtypes were achieved in this low prevalence population.

AB - INTRODUCTION: Subjective cognitive decline (SCD) is a risk condition for dementia, including dementia of Alzheimer type (DAT).METHODS: We report sensitivity, specificity, positive and negative predictive values (PPV, NPV) for conversion to all-cause dementia, and DAT in different SCD types (decline in memory, assocated worries, longitudinal consitency, of the AgeCoDe study (n = 2.402, 12 years follow-up).RESULTS: 82.7% of those converting to any dementia and 84.4% of those converting with DAT at follow-up, reported memory decline and fulfilled criteria of SCD at least at one time point before. SCD with worries at two consecutive time points showed a specificity of 92.2% for any dementia and also for DAT as well as a PPV of 44.3% for any dementia and of 36.9% for DAT at follow-up at the expense of low sensitivity.DISCUSSION: Different SCD subtypes were either sensitive or specific for future all-cause dementia and DAT in cognitively unimpaired individuals. Modest PPV of the most specific SCD subtypes were achieved in this low prevalence population.

U2 - 10.1002/alz.12163

DO - 10.1002/alz.12163

M3 - SCORING: Journal article

C2 - 33140565

VL - 16

SP - 1745

EP - 1749

JO - ALZHEIMERS DEMENT

JF - ALZHEIMERS DEMENT

SN - 1552-5260

IS - 12

ER -