POTS following traumatic stress: interacting central and intracardiac neural control?
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POTS following traumatic stress: interacting central and intracardiac neural control? / Meyer, Christian; Mühlsteff, Jens; Drexel, Thomas; Eickholt, Christian; Kelm, Malte; Zahiragic, Lejla; Ziegler, Dan.
in: J DIABETES COMPLICAT, Jahrgang 29, Nr. 3, 04.2015, S. 459-461.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - POTS following traumatic stress: interacting central and intracardiac neural control?
AU - Meyer, Christian
AU - Mühlsteff, Jens
AU - Drexel, Thomas
AU - Eickholt, Christian
AU - Kelm, Malte
AU - Zahiragic, Lejla
AU - Ziegler, Dan
N1 - Copyright © 2015 Elsevier Inc. All rights reserved.
PY - 2015/4
Y1 - 2015/4
N2 - Cardiovascular autonomic dysfunction is one of the most overlooked complications in patients with diabetes. We report the case of a 19-year-old woman with a 4-year history of diabetes referred due to palpitations and light-headedness following traumatic stress. Rise of heart rate and blood pressure during tilt table testing indicated hyperadrenergic postural orthstatic tachycardia syndrome (POTS). Elevated blood pressure variability, an indirect parameter of increased sympathetic activity, remained almost stable during orthostatic stress. Short-term treatment with ivabradine in combination with psychosocial support alleviated POTS-related symptoms. Our findings suggest that traumatic stress in patients with type 1 diabetes mellitus might translate into disturbed neural heart rate control due to a central, ephemeral alteration in autonomic balance.
AB - Cardiovascular autonomic dysfunction is one of the most overlooked complications in patients with diabetes. We report the case of a 19-year-old woman with a 4-year history of diabetes referred due to palpitations and light-headedness following traumatic stress. Rise of heart rate and blood pressure during tilt table testing indicated hyperadrenergic postural orthstatic tachycardia syndrome (POTS). Elevated blood pressure variability, an indirect parameter of increased sympathetic activity, remained almost stable during orthostatic stress. Short-term treatment with ivabradine in combination with psychosocial support alleviated POTS-related symptoms. Our findings suggest that traumatic stress in patients with type 1 diabetes mellitus might translate into disturbed neural heart rate control due to a central, ephemeral alteration in autonomic balance.
KW - Central Nervous System/physiology
KW - Diabetes Mellitus, Type 1/complications
KW - Female
KW - Heart/innervation
KW - Humans
KW - Nerve Net/physiopathology
KW - Postural Orthostatic Tachycardia Syndrome/etiology
KW - Stress Disorders, Traumatic/complications
KW - Young Adult
U2 - 10.1016/j.jdiacomp.2015.02.003
DO - 10.1016/j.jdiacomp.2015.02.003
M3 - SCORING: Journal article
C2 - 25708501
VL - 29
SP - 459
EP - 461
JO - J DIABETES COMPLICAT
JF - J DIABETES COMPLICAT
SN - 1056-8727
IS - 3
ER -