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Postoperative bleeding risk for oral surgery under continued rivaroxaban anticoagulant therapy

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Postoperative bleeding risk for oral surgery under continued rivaroxaban anticoagulant therapy. / Hanken, Henning; Gröbe, Alexander; Heiland, Max; Smeets, Ralf; Kluwe, Lan; Wikner, Johannes; Koehnke, Robert; Al-Dam, Ahmed; Eichhorn, Wolfgang.

in: CLIN ORAL INVEST, Jahrgang 20, Nr. 6, 07.2016, S. 1279-82.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Hanken, H, Gröbe, A, Heiland, M, Smeets, R, Kluwe, L, Wikner, J, Koehnke, R, Al-Dam, A & Eichhorn, W 2016, 'Postoperative bleeding risk for oral surgery under continued rivaroxaban anticoagulant therapy', CLIN ORAL INVEST, Jg. 20, Nr. 6, S. 1279-82. https://doi.org/10.1007/s00784-015-1627-9

APA

Hanken, H., Gröbe, A., Heiland, M., Smeets, R., Kluwe, L., Wikner, J., Koehnke, R., Al-Dam, A., & Eichhorn, W. (2016). Postoperative bleeding risk for oral surgery under continued rivaroxaban anticoagulant therapy. CLIN ORAL INVEST, 20(6), 1279-82. https://doi.org/10.1007/s00784-015-1627-9

Vancouver

Hanken H, Gröbe A, Heiland M, Smeets R, Kluwe L, Wikner J et al. Postoperative bleeding risk for oral surgery under continued rivaroxaban anticoagulant therapy. CLIN ORAL INVEST. 2016 Jul;20(6):1279-82. https://doi.org/10.1007/s00784-015-1627-9

Bibtex

@article{8226469c85c841608f1d58d7c9abc671,
title = "Postoperative bleeding risk for oral surgery under continued rivaroxaban anticoagulant therapy",
abstract = "OBJECTIVES: The purpose of this study was to assess the risk of postoperative bleeding complications after oral procedures performed under continued mono or dual anticoagulation therapy with rivaroxaban (and aspirin).METHODS: This retrospective single-center observational study included 52 oral procedures performed under continued oral anticoagulant therapy with rivaroxaban (20 mg/day). Among them, two procedures were performed under continued dual therapy with aspirin (100 mg/day) added to the regimen. Postoperative bleeding events were compared with 285 oral procedures in patients without any anticoagulation/antiplatelet therapy.RESULTS: Postoperative bleeding complications after oral surgery occurred significantly more often in patients under continued rivaroxaban therapy (11.5 %) than in the control cases without anticoagulation/antiplatelet medication (0.7 %). All of the bleeding events were manageable: Two of them were treated with local compression, three by applying new fibrin glue with (one case) or without (two cases) secondary sutures, one occurred during a weekend and was therefore treated under inpatient conditions with suture replacement. All postoperative bleeding episodes occurred during the first postoperative week.CONCLUSIONS: According to our data, continued anticoagulation therapy with rivaroxaban significantly increases postoperative bleeding risk for oral surgical procedures, although the bleeding events were manageable.CLINICAL RELEVANCE: Oral surgeons, cardiologists, general physicians, and patients should be aware of the increased bleeding risk after oral surgical procedures. Close observation up to 1 week postoperatively is advisable to prevent excessive bleeding.",
author = "Henning Hanken and Alexander Gr{\"o}be and Max Heiland and Ralf Smeets and Lan Kluwe and Johannes Wikner and Robert Koehnke and Ahmed Al-Dam and Wolfgang Eichhorn",
year = "2016",
month = jul,
doi = "10.1007/s00784-015-1627-9",
language = "English",
volume = "20",
pages = "1279--82",
journal = "CLIN ORAL INVEST",
issn = "1432-6981",
publisher = "Springer",
number = "6",

}

RIS

TY - JOUR

T1 - Postoperative bleeding risk for oral surgery under continued rivaroxaban anticoagulant therapy

AU - Hanken, Henning

AU - Gröbe, Alexander

AU - Heiland, Max

AU - Smeets, Ralf

AU - Kluwe, Lan

AU - Wikner, Johannes

AU - Koehnke, Robert

AU - Al-Dam, Ahmed

AU - Eichhorn, Wolfgang

PY - 2016/7

Y1 - 2016/7

N2 - OBJECTIVES: The purpose of this study was to assess the risk of postoperative bleeding complications after oral procedures performed under continued mono or dual anticoagulation therapy with rivaroxaban (and aspirin).METHODS: This retrospective single-center observational study included 52 oral procedures performed under continued oral anticoagulant therapy with rivaroxaban (20 mg/day). Among them, two procedures were performed under continued dual therapy with aspirin (100 mg/day) added to the regimen. Postoperative bleeding events were compared with 285 oral procedures in patients without any anticoagulation/antiplatelet therapy.RESULTS: Postoperative bleeding complications after oral surgery occurred significantly more often in patients under continued rivaroxaban therapy (11.5 %) than in the control cases without anticoagulation/antiplatelet medication (0.7 %). All of the bleeding events were manageable: Two of them were treated with local compression, three by applying new fibrin glue with (one case) or without (two cases) secondary sutures, one occurred during a weekend and was therefore treated under inpatient conditions with suture replacement. All postoperative bleeding episodes occurred during the first postoperative week.CONCLUSIONS: According to our data, continued anticoagulation therapy with rivaroxaban significantly increases postoperative bleeding risk for oral surgical procedures, although the bleeding events were manageable.CLINICAL RELEVANCE: Oral surgeons, cardiologists, general physicians, and patients should be aware of the increased bleeding risk after oral surgical procedures. Close observation up to 1 week postoperatively is advisable to prevent excessive bleeding.

AB - OBJECTIVES: The purpose of this study was to assess the risk of postoperative bleeding complications after oral procedures performed under continued mono or dual anticoagulation therapy with rivaroxaban (and aspirin).METHODS: This retrospective single-center observational study included 52 oral procedures performed under continued oral anticoagulant therapy with rivaroxaban (20 mg/day). Among them, two procedures were performed under continued dual therapy with aspirin (100 mg/day) added to the regimen. Postoperative bleeding events were compared with 285 oral procedures in patients without any anticoagulation/antiplatelet therapy.RESULTS: Postoperative bleeding complications after oral surgery occurred significantly more often in patients under continued rivaroxaban therapy (11.5 %) than in the control cases without anticoagulation/antiplatelet medication (0.7 %). All of the bleeding events were manageable: Two of them were treated with local compression, three by applying new fibrin glue with (one case) or without (two cases) secondary sutures, one occurred during a weekend and was therefore treated under inpatient conditions with suture replacement. All postoperative bleeding episodes occurred during the first postoperative week.CONCLUSIONS: According to our data, continued anticoagulation therapy with rivaroxaban significantly increases postoperative bleeding risk for oral surgical procedures, although the bleeding events were manageable.CLINICAL RELEVANCE: Oral surgeons, cardiologists, general physicians, and patients should be aware of the increased bleeding risk after oral surgical procedures. Close observation up to 1 week postoperatively is advisable to prevent excessive bleeding.

U2 - 10.1007/s00784-015-1627-9

DO - 10.1007/s00784-015-1627-9

M3 - SCORING: Journal article

C2 - 26498769

VL - 20

SP - 1279

EP - 1282

JO - CLIN ORAL INVEST

JF - CLIN ORAL INVEST

SN - 1432-6981

IS - 6

ER -