Postmortem Stability of SARS-CoV-2 in Nasopharyngeal Mucosa

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Postmortem Stability of SARS-CoV-2 in Nasopharyngeal Mucosa. / Heinrich, Fabian; Meißner, Kira; Langenwalder, Felicia; Püschel, Klaus; Hoffmann, Armin; Lütgehetmann, Marc; Aepfelbacher, Martin; Bibiza-Freiwald, Eric; Pfefferle, Susanne; Heinemann, Axel.

in: EMERG INFECT DIS, Jahrgang 27, Nr. 1, 01.2021, S. 329-331.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungAndere (Vorworte u.ä.)Forschung

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@article{70d534f9cb0e426f9a282967be9cd9da,
title = "Postmortem Stability of SARS-CoV-2 in Nasopharyngeal Mucosa",
abstract = "Analyses of infection chains have demonstrated that severe acute respiratory syndrome coronavirus 2 is highly transmissive. However, data on postmortem stability and infectivity are lacking. Our finding of nasopharyngeal viral RNA stability in 79 corpses showed no time-dependent decrease. Maintained infectivity is supported by virus isolation up to 35 hours postmortem.",
keywords = "COVID-19/virology, Cadaver, Humans, Nasopharynx/virology, RNA, Viral/isolation & purification, Respiratory Mucosa/virology, SARS-CoV-2/isolation & purification",
author = "Fabian Heinrich and Kira Mei{\ss}ner and Felicia Langenwalder and Klaus P{\"u}schel and Armin Hoffmann and Marc L{\"u}tgehetmann and Martin Aepfelbacher and Eric Bibiza-Freiwald and Susanne Pfefferle and Axel Heinemann",
year = "2021",
month = jan,
doi = "10.3201/eid2701.203112",
language = "English",
volume = "27",
pages = "329--331",
journal = "EMERG INFECT DIS",
issn = "1080-6040",
publisher = "Centers for Disease Control and Prevention (CDC)",
number = "1",

}

RIS

TY - JOUR

T1 - Postmortem Stability of SARS-CoV-2 in Nasopharyngeal Mucosa

AU - Heinrich, Fabian

AU - Meißner, Kira

AU - Langenwalder, Felicia

AU - Püschel, Klaus

AU - Hoffmann, Armin

AU - Lütgehetmann, Marc

AU - Aepfelbacher, Martin

AU - Bibiza-Freiwald, Eric

AU - Pfefferle, Susanne

AU - Heinemann, Axel

PY - 2021/1

Y1 - 2021/1

N2 - Analyses of infection chains have demonstrated that severe acute respiratory syndrome coronavirus 2 is highly transmissive. However, data on postmortem stability and infectivity are lacking. Our finding of nasopharyngeal viral RNA stability in 79 corpses showed no time-dependent decrease. Maintained infectivity is supported by virus isolation up to 35 hours postmortem.

AB - Analyses of infection chains have demonstrated that severe acute respiratory syndrome coronavirus 2 is highly transmissive. However, data on postmortem stability and infectivity are lacking. Our finding of nasopharyngeal viral RNA stability in 79 corpses showed no time-dependent decrease. Maintained infectivity is supported by virus isolation up to 35 hours postmortem.

KW - COVID-19/virology

KW - Cadaver

KW - Humans

KW - Nasopharynx/virology

KW - RNA, Viral/isolation & purification

KW - Respiratory Mucosa/virology

KW - SARS-CoV-2/isolation & purification

U2 - 10.3201/eid2701.203112

DO - 10.3201/eid2701.203112

M3 - Other (editorial matter etc.)

C2 - 33327991

VL - 27

SP - 329

EP - 331

JO - EMERG INFECT DIS

JF - EMERG INFECT DIS

SN - 1080-6040

IS - 1

ER -