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[Photoprotective mechanisms of human skin. Modulation by oligonucleotides]

Standard

[Photoprotective mechanisms of human skin. Modulation by oligonucleotides]. / Hadshiew, I M; Eller, M S; Moll, Ingrid; Gilchrest, B A.

in: HAUTARZT, Jahrgang 53, Nr. 3, 3, 2002, S. 167-173.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Hadshiew, IM, Eller, MS, Moll, I & Gilchrest, BA 2002, '[Photoprotective mechanisms of human skin. Modulation by oligonucleotides]', HAUTARZT, Jg. 53, Nr. 3, 3, S. 167-173. <http://www.ncbi.nlm.nih.gov/pubmed/11974587?dopt=Citation>

APA

Hadshiew, I. M., Eller, M. S., Moll, I., & Gilchrest, B. A. (2002). [Photoprotective mechanisms of human skin. Modulation by oligonucleotides]. HAUTARZT, 53(3), 167-173. [3]. http://www.ncbi.nlm.nih.gov/pubmed/11974587?dopt=Citation

Vancouver

Hadshiew IM, Eller MS, Moll I, Gilchrest BA. [Photoprotective mechanisms of human skin. Modulation by oligonucleotides]. HAUTARZT. 2002;53(3):167-173. 3.

Bibtex

@article{d7f6df732ad54fe08db176c54ae15cf6,
title = "[Photoprotective mechanisms of human skin. Modulation by oligonucleotides]",
abstract = "There are at least two classic photoprotective DNA damage responses that can be elicited by UV exposure: induction of melanogenesis (tanning) and enhancement of DNA repair. Both mechanisms are mediated, at least in part, by the tumor-suppressor protein and transcription factor p53. Both of these responses can be induced in vitro as well as in vivo by small DNA fragments of specific sequences, without prior induction of actual DNA damage. The topical application of such fragments onto human skin might enhance photoprotection in human skin, as typically elicited by gradual sun exposure. The induction of photoprotection by this means, however, would not bear the mutagenic and carcinogenic risk of exposure to natural sunlight.",
author = "Hadshiew, {I M} and Eller, {M S} and Ingrid Moll and Gilchrest, {B A}",
year = "2002",
language = "Deutsch",
volume = "53",
pages = "167--173",
journal = "HAUTARZT",
issn = "0017-8470",
publisher = "Springer",
number = "3",

}

RIS

TY - JOUR

T1 - [Photoprotective mechanisms of human skin. Modulation by oligonucleotides]

AU - Hadshiew, I M

AU - Eller, M S

AU - Moll, Ingrid

AU - Gilchrest, B A

PY - 2002

Y1 - 2002

N2 - There are at least two classic photoprotective DNA damage responses that can be elicited by UV exposure: induction of melanogenesis (tanning) and enhancement of DNA repair. Both mechanisms are mediated, at least in part, by the tumor-suppressor protein and transcription factor p53. Both of these responses can be induced in vitro as well as in vivo by small DNA fragments of specific sequences, without prior induction of actual DNA damage. The topical application of such fragments onto human skin might enhance photoprotection in human skin, as typically elicited by gradual sun exposure. The induction of photoprotection by this means, however, would not bear the mutagenic and carcinogenic risk of exposure to natural sunlight.

AB - There are at least two classic photoprotective DNA damage responses that can be elicited by UV exposure: induction of melanogenesis (tanning) and enhancement of DNA repair. Both mechanisms are mediated, at least in part, by the tumor-suppressor protein and transcription factor p53. Both of these responses can be induced in vitro as well as in vivo by small DNA fragments of specific sequences, without prior induction of actual DNA damage. The topical application of such fragments onto human skin might enhance photoprotection in human skin, as typically elicited by gradual sun exposure. The induction of photoprotection by this means, however, would not bear the mutagenic and carcinogenic risk of exposure to natural sunlight.

M3 - SCORING: Zeitschriftenaufsatz

VL - 53

SP - 167

EP - 173

JO - HAUTARZT

JF - HAUTARZT

SN - 0017-8470

IS - 3

M1 - 3

ER -