Persisting hepatitis E virus infection leading to liver cirrhosis despite recovery of the immune system in an HIV-infected patient
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Persisting hepatitis E virus infection leading to liver cirrhosis despite recovery of the immune system in an HIV-infected patient. / Ingiliz, P; Mayr, C; Obermeier, M; Herbst, H; Polywka, S; Pischke, S.
in: CLIN RES HEPATOL GAS, Jahrgang 40, Nr. 3, 06.2016, S. e23-5.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Persisting hepatitis E virus infection leading to liver cirrhosis despite recovery of the immune system in an HIV-infected patient
AU - Ingiliz, P
AU - Mayr, C
AU - Obermeier, M
AU - Herbst, H
AU - Polywka, S
AU - Pischke, S
N1 - Copyright © 2016 Elsevier Masson SAS. All rights reserved.
PY - 2016/6
Y1 - 2016/6
N2 - Chronic hepatitis E has been described several times in strongly immunosuppressed HIV-patients. We describe the persistence of HEV-infection in an HIV-patient despite a restored immune response. This case demonstrates that HEV-infection can persist in formerly immunosuppressed individuals irrespective of the current immune status. Persisting HEV-infection can lead to chronic inflammation and liver cirrhosis. Physicians should be aware of the possibility of chronic hepatitis E even in patients that are not any longer immunocompromised. However, ribavirin is an efficient treatment option.
AB - Chronic hepatitis E has been described several times in strongly immunosuppressed HIV-patients. We describe the persistence of HEV-infection in an HIV-patient despite a restored immune response. This case demonstrates that HEV-infection can persist in formerly immunosuppressed individuals irrespective of the current immune status. Persisting HEV-infection can lead to chronic inflammation and liver cirrhosis. Physicians should be aware of the possibility of chronic hepatitis E even in patients that are not any longer immunocompromised. However, ribavirin is an efficient treatment option.
KW - Journal Article
U2 - 10.1016/j.clinre.2016.01.005
DO - 10.1016/j.clinre.2016.01.005
M3 - SCORING: Journal article
C2 - 27055386
VL - 40
SP - e23-5
JO - CLIN RES HEPATOL GAS
JF - CLIN RES HEPATOL GAS
SN - 2210-7401
IS - 3
ER -