Perioperative troponin surveillance in major noncardiac surgery - a narrative review
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Perioperative troponin surveillance in major noncardiac surgery - a narrative review. / Chew, Michelle S; Saugel, Bernd; Lurati-Buse, Giovanna.
in: BRIT J ANAESTH, Jahrgang 130, Nr. 1, 01.2023, S. 21-28.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung
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TY - JOUR
T1 - Perioperative troponin surveillance in major noncardiac surgery - a narrative review
AU - Chew, Michelle S
AU - Saugel, Bernd
AU - Lurati-Buse, Giovanna
N1 - Copyright © 2022 The Authors. Published by Elsevier Ltd.. All rights reserved.
PY - 2023/1
Y1 - 2023/1
N2 - Myocardial injury is now an acknowledged complication in patients undergoing noncardiac surgery. Heterogeneity in the definitions of myocardial injury contributes to difficulty in evaluating the value of cardiac troponins (cTns) measurement in perioperative care. Pre-, post-, and peri-operatively increased cTns are encompassed by the umbrella term 'myocardial injury' and are likely to reflect different pathophysiological mechanisms. Increased cTns are independently associated with cardiovascular and non-cardiovascular complications, poor short-term and long-term cardiovascular outcomes, and increased mortality. Preoperative measurement of cTns aids preoperative risk stratification beyond the Revised Cardiac Risk Index. Systematic measurement detects acute perioperative increases and allows early identification of acute myocardial injury. Common definitions and standards for reporting are a prerequisite for designing impactful future trials and perioperative management strategies.
AB - Myocardial injury is now an acknowledged complication in patients undergoing noncardiac surgery. Heterogeneity in the definitions of myocardial injury contributes to difficulty in evaluating the value of cardiac troponins (cTns) measurement in perioperative care. Pre-, post-, and peri-operatively increased cTns are encompassed by the umbrella term 'myocardial injury' and are likely to reflect different pathophysiological mechanisms. Increased cTns are independently associated with cardiovascular and non-cardiovascular complications, poor short-term and long-term cardiovascular outcomes, and increased mortality. Preoperative measurement of cTns aids preoperative risk stratification beyond the Revised Cardiac Risk Index. Systematic measurement detects acute perioperative increases and allows early identification of acute myocardial injury. Common definitions and standards for reporting are a prerequisite for designing impactful future trials and perioperative management strategies.
KW - Humans
KW - Troponin
KW - Perioperative Care
KW - Risk Assessment
KW - Postoperative Complications/diagnosis
U2 - 10.1016/j.bja.2022.08.041
DO - 10.1016/j.bja.2022.08.041
M3 - SCORING: Review article
C2 - 36464518
VL - 130
SP - 21
EP - 28
JO - BRIT J ANAESTH
JF - BRIT J ANAESTH
SN - 0007-0912
IS - 1
ER -