PAS-positive loops and networks as a prognostic indicator in cutaneous malignant melanoma.
Standard
PAS-positive loops and networks as a prognostic indicator in cutaneous malignant melanoma. / Dahl, Anka; Mangold, U; Moll, Ingrid; Schumacher, U.
in: J PATHOL, Jahrgang 195, Nr. 5, 5, 2001, S. 537-542.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - PAS-positive loops and networks as a prognostic indicator in cutaneous malignant melanoma.
AU - Dahl, Anka
AU - Mangold, U
AU - Moll, Ingrid
AU - Schumacher, U
PY - 2001
Y1 - 2001
N2 - Recently, microvascular channels, as detected by PAS histochemistry, were positively correlated with poor prognosis in uveal malignant melanoma. Since uveal melanomas are not penetrated by lymphatic vessels, while cutaneous melanomas are, the question arises as to whether these loops and networks are also of prognostic relevance in cutaneous melanoma. Histochemically and immunohistochemically detected loops and networks in 100 cases of cutaneous malignant melanoma were correlated with the occurrence of metastasis in a 10-year follow-up study. To detect these patterns, the significance of various methods (PAS reaction with/without nuclear counterstain, anti-laminin immunohistochemistry) was investigated. The presence of loops and networks was a highly significant prognostic marker (p
AB - Recently, microvascular channels, as detected by PAS histochemistry, were positively correlated with poor prognosis in uveal malignant melanoma. Since uveal melanomas are not penetrated by lymphatic vessels, while cutaneous melanomas are, the question arises as to whether these loops and networks are also of prognostic relevance in cutaneous melanoma. Histochemically and immunohistochemically detected loops and networks in 100 cases of cutaneous malignant melanoma were correlated with the occurrence of metastasis in a 10-year follow-up study. To detect these patterns, the significance of various methods (PAS reaction with/without nuclear counterstain, anti-laminin immunohistochemistry) was investigated. The presence of loops and networks was a highly significant prognostic marker (p
M3 - SCORING: Zeitschriftenaufsatz
VL - 195
SP - 537
EP - 542
JO - J PATHOL
JF - J PATHOL
SN - 0022-3417
IS - 5
M1 - 5
ER -
