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Partin Tables cannot accurately predict the pathological stage at radical prostatectomy.

Standard

Partin Tables cannot accurately predict the pathological stage at radical prostatectomy. / Bhojani, N; Ahyai, S; Graefen, Markus; Capitanio, U; Suardi, N; Shariat, S F; Jeldres, C; Erbersdobler, A; Schlomm, T; Haese, Alexander; Steuber, Thomas; Heinzer, Hans; Montorsi, F; Huland, Hartwig; Karakiewicz, P I.

in: EJSO-EUR J SURG ONC, Jahrgang 35, Nr. 2, 2, 2009, S. 123-128.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Bhojani, N, Ahyai, S, Graefen, M, Capitanio, U, Suardi, N, Shariat, SF, Jeldres, C, Erbersdobler, A, Schlomm, T, Haese, A, Steuber, T, Heinzer, H, Montorsi, F, Huland, H & Karakiewicz, PI 2009, 'Partin Tables cannot accurately predict the pathological stage at radical prostatectomy.', EJSO-EUR J SURG ONC, Jg. 35, Nr. 2, 2, S. 123-128. <http://www.ncbi.nlm.nih.gov/pubmed/18786800?dopt=Citation>

APA

Bhojani, N., Ahyai, S., Graefen, M., Capitanio, U., Suardi, N., Shariat, S. F., Jeldres, C., Erbersdobler, A., Schlomm, T., Haese, A., Steuber, T., Heinzer, H., Montorsi, F., Huland, H., & Karakiewicz, P. I. (2009). Partin Tables cannot accurately predict the pathological stage at radical prostatectomy. EJSO-EUR J SURG ONC, 35(2), 123-128. [2]. http://www.ncbi.nlm.nih.gov/pubmed/18786800?dopt=Citation

Vancouver

Bhojani N, Ahyai S, Graefen M, Capitanio U, Suardi N, Shariat SF et al. Partin Tables cannot accurately predict the pathological stage at radical prostatectomy. EJSO-EUR J SURG ONC. 2009;35(2):123-128. 2.

Bibtex

@article{1bea87e4ebed4f1fb2aaddf54580619d,
title = "Partin Tables cannot accurately predict the pathological stage at radical prostatectomy.",
abstract = "PURPOSE: The Partin Tables represent the most commonly used staging tool for radical prostatectomy (RP) candidates. The Partin Tables' predictions are used to guide the type (nerve preserving RP) and/or the extent (RP with wide resection) of RP. We examined the ability of the Partin Tables' predictions incorrectly assigning the stage at RP. METHODS: The testing of the Partin Tables (external validation) was based on 3105 patients treated with RP at a single European institution. Standard validation metrics were used (area under the receiver operating characteristics curve, AUC) to test the three endpoints predicted by the Partin Tables, namely the presence of extracapsular extension (ECE), seminal vesicle invasion (SVI), and lymph node invasion (LNI). RESULTS: Ideal predictions are denoted with 100% accuracy vs. 50% for entirely random predictions. For the 2001 version of the Tables the accuracy defined by the AUC was 79.7, 77.8, and 73.0 for ECE, SVI, and LNI, respectively. For the 2007 version of the Tables the corresponding accuracy estimates were 79.8, 80.5, and 76.2. The relationship between predicted probabilities and observed rates was poor. CONCLUSION: The Partin Tables are meant to guide clinicians about the safety of nerve bundle preservation at RP, about the need for seminal vesicle resection or for lymphadenectomy. Therefore, the use of the Partin Tables predictions may significantly affect the type and/or the extent of RP. In their present format the Partin Tables are not accurate enough to influence the pre-operative decision making regarding the type or extent of RP.",
author = "N Bhojani and S Ahyai and Markus Graefen and U Capitanio and N Suardi and Shariat, {S F} and C Jeldres and A Erbersdobler and T Schlomm and Alexander Haese and Thomas Steuber and Hans Heinzer and F Montorsi and Hartwig Huland and Karakiewicz, {P I}",
year = "2009",
language = "Deutsch",
volume = "35",
pages = "123--128",
journal = "EJSO-EUR J SURG ONC",
issn = "0748-7983",
publisher = "W.B. Saunders Ltd",
number = "2",

}

RIS

TY - JOUR

T1 - Partin Tables cannot accurately predict the pathological stage at radical prostatectomy.

AU - Bhojani, N

AU - Ahyai, S

AU - Graefen, Markus

AU - Capitanio, U

AU - Suardi, N

AU - Shariat, S F

AU - Jeldres, C

AU - Erbersdobler, A

AU - Schlomm, T

AU - Haese, Alexander

AU - Steuber, Thomas

AU - Heinzer, Hans

AU - Montorsi, F

AU - Huland, Hartwig

AU - Karakiewicz, P I

PY - 2009

Y1 - 2009

N2 - PURPOSE: The Partin Tables represent the most commonly used staging tool for radical prostatectomy (RP) candidates. The Partin Tables' predictions are used to guide the type (nerve preserving RP) and/or the extent (RP with wide resection) of RP. We examined the ability of the Partin Tables' predictions incorrectly assigning the stage at RP. METHODS: The testing of the Partin Tables (external validation) was based on 3105 patients treated with RP at a single European institution. Standard validation metrics were used (area under the receiver operating characteristics curve, AUC) to test the three endpoints predicted by the Partin Tables, namely the presence of extracapsular extension (ECE), seminal vesicle invasion (SVI), and lymph node invasion (LNI). RESULTS: Ideal predictions are denoted with 100% accuracy vs. 50% for entirely random predictions. For the 2001 version of the Tables the accuracy defined by the AUC was 79.7, 77.8, and 73.0 for ECE, SVI, and LNI, respectively. For the 2007 version of the Tables the corresponding accuracy estimates were 79.8, 80.5, and 76.2. The relationship between predicted probabilities and observed rates was poor. CONCLUSION: The Partin Tables are meant to guide clinicians about the safety of nerve bundle preservation at RP, about the need for seminal vesicle resection or for lymphadenectomy. Therefore, the use of the Partin Tables predictions may significantly affect the type and/or the extent of RP. In their present format the Partin Tables are not accurate enough to influence the pre-operative decision making regarding the type or extent of RP.

AB - PURPOSE: The Partin Tables represent the most commonly used staging tool for radical prostatectomy (RP) candidates. The Partin Tables' predictions are used to guide the type (nerve preserving RP) and/or the extent (RP with wide resection) of RP. We examined the ability of the Partin Tables' predictions incorrectly assigning the stage at RP. METHODS: The testing of the Partin Tables (external validation) was based on 3105 patients treated with RP at a single European institution. Standard validation metrics were used (area under the receiver operating characteristics curve, AUC) to test the three endpoints predicted by the Partin Tables, namely the presence of extracapsular extension (ECE), seminal vesicle invasion (SVI), and lymph node invasion (LNI). RESULTS: Ideal predictions are denoted with 100% accuracy vs. 50% for entirely random predictions. For the 2001 version of the Tables the accuracy defined by the AUC was 79.7, 77.8, and 73.0 for ECE, SVI, and LNI, respectively. For the 2007 version of the Tables the corresponding accuracy estimates were 79.8, 80.5, and 76.2. The relationship between predicted probabilities and observed rates was poor. CONCLUSION: The Partin Tables are meant to guide clinicians about the safety of nerve bundle preservation at RP, about the need for seminal vesicle resection or for lymphadenectomy. Therefore, the use of the Partin Tables predictions may significantly affect the type and/or the extent of RP. In their present format the Partin Tables are not accurate enough to influence the pre-operative decision making regarding the type or extent of RP.

M3 - SCORING: Zeitschriftenaufsatz

VL - 35

SP - 123

EP - 128

JO - EJSO-EUR J SURG ONC

JF - EJSO-EUR J SURG ONC

SN - 0748-7983

IS - 2

M1 - 2

ER -