PortalPublikationenOxirapentyns F-K from the marine-sediment-derived fungus Isa...

Oxirapentyns F-K from the marine-sediment-derived fungus Isaria felina KMM 4639

Standard

Oxirapentyns F-K from the marine-sediment-derived fungus Isaria felina KMM 4639. / Yurchenko, Anton N; Smetanina, Olga F; Kalinovsky, Anatoly I; Pushilin, Michael A; Glazunov, Valeriy P; Khudyakova, Yuliya V; Kirichuk, Natalya N; Ermakova, Svetlana P; Dyshlovoy, Sergey A; Yurchenko, Ekaterina A; Afiyatullov, Shamil Sh.

in: J NAT PROD, Jahrgang 77, Nr. 6, 27.06.2014, S. 1321-8.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Yurchenko, AN, Smetanina, OF, Kalinovsky, AI, Pushilin, MA, Glazunov, VP, Khudyakova, YV, Kirichuk, NN, Ermakova, SP, Dyshlovoy, SA, Yurchenko, EA & Afiyatullov, SS 2014, 'Oxirapentyns F-K from the marine-sediment-derived fungus Isaria felina KMM 4639', J NAT PROD, Jg. 77, Nr. 6, S. 1321-8. https://doi.org/10.1021/np500014m

APA

Yurchenko, A. N., Smetanina, O. F., Kalinovsky, A. I., Pushilin, M. A., Glazunov, V. P., Khudyakova, Y. V., Kirichuk, N. N., Ermakova, S. P., Dyshlovoy, S. A., Yurchenko, E. A., & Afiyatullov, S. S. (2014). Oxirapentyns F-K from the marine-sediment-derived fungus Isaria felina KMM 4639. J NAT PROD, 77(6), 1321-8. https://doi.org/10.1021/np500014m

Vancouver

Yurchenko AN, Smetanina OF, Kalinovsky AI, Pushilin MA, Glazunov VP, Khudyakova YV et al. Oxirapentyns F-K from the marine-sediment-derived fungus Isaria felina KMM 4639. J NAT PROD. 2014 Jun 27;77(6):1321-8. https://doi.org/10.1021/np500014m

Bibtex

@article{de8fe8a58c144f3ea1c32c55016c9d74,
title = "Oxirapentyns F-K from the marine-sediment-derived fungus Isaria felina KMM 4639",
abstract = "Six new highly oxygenated chromene derivatives, oxirapentyns F-K (2-7), one new polyketide (8), one new benzofurane (9), and two known cyclodepsipeptides, isoisariin B and isaridin E, were isolated from the lipophilic extract of the marine-derived fungus Isaria felina KMM 4639. The structures of compounds 2-9 were determined using spectroscopic methods. The relative configurations of compounds 2-7 were established through a combination of NOE data and spin coupling constants, and these results were confirmed by X-ray crystallographic analysis of 4. The absolute structures of all oxirapentyns were assumed based on their biogenetic relationship and confirmed using the modified Mosher's method on 2 and 7. Isariketide (8) showed moderate cytotoxicity toward HL-60 cells.",
keywords = "Alkynes, Antineoplastic Agents, Benzopyrans, Cell Survival, Crystallography, X-Ray, Depsipeptides, Drug Screening Assays, Antitumor, Geologic Sediments, HL-60 Cells, Humans, Hypocreales, Marine Biology, Microbial Sensitivity Tests, Molecular Conformation, Molecular Structure, Nuclear Magnetic Resonance, Biomolecular, Oceans and Seas",
author = "Yurchenko, {Anton N} and Smetanina, {Olga F} and Kalinovsky, {Anatoly I} and Pushilin, {Michael A} and Glazunov, {Valeriy P} and Khudyakova, {Yuliya V} and Kirichuk, {Natalya N} and Ermakova, {Svetlana P} and Dyshlovoy, {Sergey A} and Yurchenko, {Ekaterina A} and Afiyatullov, {Shamil Sh}",
year = "2014",
month = jun,
day = "27",
doi = "10.1021/np500014m",
language = "English",
volume = "77",
pages = "1321--8",
journal = "J NAT PROD",
issn = "0163-3864",
publisher = "American Chemical Society",
number = "6",

}

RIS

TY - JOUR

T1 - Oxirapentyns F-K from the marine-sediment-derived fungus Isaria felina KMM 4639

AU - Yurchenko, Anton N

AU - Smetanina, Olga F

AU - Kalinovsky, Anatoly I

AU - Pushilin, Michael A

AU - Glazunov, Valeriy P

AU - Khudyakova, Yuliya V

AU - Kirichuk, Natalya N

AU - Ermakova, Svetlana P

AU - Dyshlovoy, Sergey A

AU - Yurchenko, Ekaterina A

AU - Afiyatullov, Shamil Sh

PY - 2014/6/27

Y1 - 2014/6/27

N2 - Six new highly oxygenated chromene derivatives, oxirapentyns F-K (2-7), one new polyketide (8), one new benzofurane (9), and two known cyclodepsipeptides, isoisariin B and isaridin E, were isolated from the lipophilic extract of the marine-derived fungus Isaria felina KMM 4639. The structures of compounds 2-9 were determined using spectroscopic methods. The relative configurations of compounds 2-7 were established through a combination of NOE data and spin coupling constants, and these results were confirmed by X-ray crystallographic analysis of 4. The absolute structures of all oxirapentyns were assumed based on their biogenetic relationship and confirmed using the modified Mosher's method on 2 and 7. Isariketide (8) showed moderate cytotoxicity toward HL-60 cells.

AB - Six new highly oxygenated chromene derivatives, oxirapentyns F-K (2-7), one new polyketide (8), one new benzofurane (9), and two known cyclodepsipeptides, isoisariin B and isaridin E, were isolated from the lipophilic extract of the marine-derived fungus Isaria felina KMM 4639. The structures of compounds 2-9 were determined using spectroscopic methods. The relative configurations of compounds 2-7 were established through a combination of NOE data and spin coupling constants, and these results were confirmed by X-ray crystallographic analysis of 4. The absolute structures of all oxirapentyns were assumed based on their biogenetic relationship and confirmed using the modified Mosher's method on 2 and 7. Isariketide (8) showed moderate cytotoxicity toward HL-60 cells.

KW - Alkynes

KW - Antineoplastic Agents

KW - Benzopyrans

KW - Cell Survival

KW - Crystallography, X-Ray

KW - Depsipeptides

KW - Drug Screening Assays, Antitumor

KW - Geologic Sediments

KW - HL-60 Cells

KW - Humans

KW - Hypocreales

KW - Marine Biology

KW - Microbial Sensitivity Tests

KW - Molecular Conformation

KW - Molecular Structure

KW - Nuclear Magnetic Resonance, Biomolecular

KW - Oceans and Seas

U2 - 10.1021/np500014m

DO - 10.1021/np500014m

M3 - SCORING: Journal article

C2 - 24911656

VL - 77

SP - 1321

EP - 1328

JO - J NAT PROD

JF - J NAT PROD

SN - 0163-3864

IS - 6

ER -