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Oxidativer Stress am retinalen Pigmentepithel - experimentelle Ansätze zur Protektion

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Oxidativer Stress am retinalen Pigmentepithel - experimentelle Ansätze zur Protektion. / Zeitz, O; Berna-Thill, M; Bartsch, U; Strauss, O; Richard, G.

in: KLIN MONATSBL AUGENH, Jahrgang 226, Nr. 1, 01.2009, S. 27-30.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Zeitz, O, Berna-Thill, M, Bartsch, U, Strauss, O & Richard, G 2009, 'Oxidativer Stress am retinalen Pigmentepithel - experimentelle Ansätze zur Protektion', KLIN MONATSBL AUGENH, Jg. 226, Nr. 1, S. 27-30. https://doi.org/10.1055/s-2008-1027600

APA

Zeitz, O., Berna-Thill, M., Bartsch, U., Strauss, O., & Richard, G. (2009). Oxidativer Stress am retinalen Pigmentepithel - experimentelle Ansätze zur Protektion. KLIN MONATSBL AUGENH, 226(1), 27-30. https://doi.org/10.1055/s-2008-1027600

Vancouver

Zeitz O, Berna-Thill M, Bartsch U, Strauss O, Richard G. Oxidativer Stress am retinalen Pigmentepithel - experimentelle Ansätze zur Protektion. KLIN MONATSBL AUGENH. 2009 Jan;226(1):27-30. https://doi.org/10.1055/s-2008-1027600

Bibtex

@article{8c38ea244998443e84fca7b8f8a30781,
title = "Oxidativer Stress am retinalen Pigmentepithel - experimentelle Ans{\"a}tze zur Protektion",
abstract = "Oxidative stress at the retinal pigment epithelium (RPE) is involved in the pathophysiology of age-related macula degeneration (ARMD). Observations on a clinical or laboratory level have revealed that supplementation of antioxidative scavengers failed in many cases. A potential therapeutic target is the cellular signal transduction cascade initiated by oxidative stress which results, e. g., in altered expression of pro- and antiagiogenic factors as well as induction of apoptosis. This review summarises the current literature on cellular effects of free radicals and deduces potential therapeutic approaches to protect the RPE from oxidative damage.",
keywords = "Animals, Antioxidants, Humans, Macular Degeneration, Oxidative Stress, Reactive Oxygen Species, Retinal Pigment Epithelium, Signal Transduction, English Abstract, Journal Article, Review",
author = "O Zeitz and M Berna-Thill and U Bartsch and O Strauss and G Richard",
year = "2009",
month = jan,
doi = "10.1055/s-2008-1027600",
language = "Deutsch",
volume = "226",
pages = "27--30",
journal = "KLIN MONATSBL AUGENH",
issn = "0023-2165",
publisher = "Ferdinand Enke Verlag",
number = "1",

}

RIS

TY - JOUR

T1 - Oxidativer Stress am retinalen Pigmentepithel - experimentelle Ansätze zur Protektion

AU - Zeitz, O

AU - Berna-Thill, M

AU - Bartsch, U

AU - Strauss, O

AU - Richard, G

PY - 2009/1

Y1 - 2009/1

N2 - Oxidative stress at the retinal pigment epithelium (RPE) is involved in the pathophysiology of age-related macula degeneration (ARMD). Observations on a clinical or laboratory level have revealed that supplementation of antioxidative scavengers failed in many cases. A potential therapeutic target is the cellular signal transduction cascade initiated by oxidative stress which results, e. g., in altered expression of pro- and antiagiogenic factors as well as induction of apoptosis. This review summarises the current literature on cellular effects of free radicals and deduces potential therapeutic approaches to protect the RPE from oxidative damage.

AB - Oxidative stress at the retinal pigment epithelium (RPE) is involved in the pathophysiology of age-related macula degeneration (ARMD). Observations on a clinical or laboratory level have revealed that supplementation of antioxidative scavengers failed in many cases. A potential therapeutic target is the cellular signal transduction cascade initiated by oxidative stress which results, e. g., in altered expression of pro- and antiagiogenic factors as well as induction of apoptosis. This review summarises the current literature on cellular effects of free radicals and deduces potential therapeutic approaches to protect the RPE from oxidative damage.

KW - Animals

KW - Antioxidants

KW - Humans

KW - Macular Degeneration

KW - Oxidative Stress

KW - Reactive Oxygen Species

KW - Retinal Pigment Epithelium

KW - Signal Transduction

KW - English Abstract

KW - Journal Article

KW - Review

U2 - 10.1055/s-2008-1027600

DO - 10.1055/s-2008-1027600

M3 - SCORING: Zeitschriftenaufsatz

C2 - 19173160

VL - 226

SP - 27

EP - 30

JO - KLIN MONATSBL AUGENH

JF - KLIN MONATSBL AUGENH

SN - 0023-2165

IS - 1

ER -