Oxazepam versus clomethiazol in alcohol withdrawal treatment.
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Oxazepam versus clomethiazol in alcohol withdrawal treatment. / De Millas, Walter; Ganzer, Florian; Kuhn, Silke; Haasen, Christian.
in: EUR ADDICT RES, Jahrgang 16, Nr. 4, 4, 2010, S. 179-184.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Oxazepam versus clomethiazol in alcohol withdrawal treatment.
AU - De Millas, Walter
AU - Ganzer, Florian
AU - Kuhn, Silke
AU - Haasen, Christian
PY - 2010
Y1 - 2010
N2 - The pharmacological management of the alcohol withdrawal syndrome associated with alcohol dependence is heterogeneous; however, according to the guidelines, clomethiazol is the standard medication in Germany. Benzodiazepines offer another safe possibility of treating alcohol withdrawal. In a retrospective study, alcohol-dependent patients treated either with oxazepam (n = 141) or clomethiazol (n = 357) were assessed with respect to the course of treatment and withdrawal symptoms. The results showed that under oxazepam treatment, there were fewer days with severe alcohol withdrawal symptoms and less severe adverse events, but patients receiving clomethiazol treatment had a more severe course of alcohol dependence. Oxazepam is a safe, efficient and cheap drug for the treatment of alcohol withdrawal symptoms, but controlled studies are needed to compare its effectiveness with that of clomethiazol.
AB - The pharmacological management of the alcohol withdrawal syndrome associated with alcohol dependence is heterogeneous; however, according to the guidelines, clomethiazol is the standard medication in Germany. Benzodiazepines offer another safe possibility of treating alcohol withdrawal. In a retrospective study, alcohol-dependent patients treated either with oxazepam (n = 141) or clomethiazol (n = 357) were assessed with respect to the course of treatment and withdrawal symptoms. The results showed that under oxazepam treatment, there were fewer days with severe alcohol withdrawal symptoms and less severe adverse events, but patients receiving clomethiazol treatment had a more severe course of alcohol dependence. Oxazepam is a safe, efficient and cheap drug for the treatment of alcohol withdrawal symptoms, but controlled studies are needed to compare its effectiveness with that of clomethiazol.
KW - Adult
KW - Humans
KW - Male
KW - Female
KW - Middle Aged
KW - Treatment Outcome
KW - Retrospective Studies
KW - Analysis of Variance
KW - Alcoholism drug therapy
KW - Chlormethiazole therapeutic use
KW - Ethanol adverse effects
KW - GABA Modulators therapeutic use
KW - Oxazepam therapeutic use
KW - Substance Withdrawal Syndrome drug therapy
KW - Adult
KW - Humans
KW - Male
KW - Female
KW - Middle Aged
KW - Treatment Outcome
KW - Retrospective Studies
KW - Analysis of Variance
KW - Alcoholism drug therapy
KW - Chlormethiazole therapeutic use
KW - Ethanol adverse effects
KW - GABA Modulators therapeutic use
KW - Oxazepam therapeutic use
KW - Substance Withdrawal Syndrome drug therapy
M3 - SCORING: Zeitschriftenaufsatz
VL - 16
SP - 179
EP - 184
JO - EUR ADDICT RES
JF - EUR ADDICT RES
SN - 1022-6877
IS - 4
M1 - 4
ER -
