Outcomes of Primary Transconjunctival 23-Gauge Vitrectomy in the Diagnosis and Treatment of Presumed Endogenous Fungal Endophthalmitis
Standard
Outcomes of Primary Transconjunctival 23-Gauge Vitrectomy in the Diagnosis and Treatment of Presumed Endogenous Fungal Endophthalmitis. / William, Antony; Spitzer, Martin S; Deuter, Christoph; Blumenstock, Gunnar; Partsch, Michael; Voykov, Bogomil; Ziemssen, Focke; Bartz-Schmidt, Karl Ulrich; Doycheva, Deshka.
in: OCUL IMMUNOL INFLAMM, Jahrgang 25, Nr. 2, 04.2017, S. 239-245.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Outcomes of Primary Transconjunctival 23-Gauge Vitrectomy in the Diagnosis and Treatment of Presumed Endogenous Fungal Endophthalmitis
AU - William, Antony
AU - Spitzer, Martin S
AU - Deuter, Christoph
AU - Blumenstock, Gunnar
AU - Partsch, Michael
AU - Voykov, Bogomil
AU - Ziemssen, Focke
AU - Bartz-Schmidt, Karl Ulrich
AU - Doycheva, Deshka
PY - 2017/4
Y1 - 2017/4
N2 - PURPOSE: To report the outcomes of primary transconjunctival 23-gauge (23-G) vitrectomy in the diagnosis and treatment of presumed endogenous fungal endophthalmitis (EFE).METHODS: Retrospective analysis of patients with EFE who underwent diagnostic transconjunctival 23-G vitrectomy at a tertiary referral center.RESULTS: Nineteen eyes of 15 patients with EFE were included in the study. Four patients had bilateral and 11 patients unilateral disease. Sixteen eyes of 15 patients underwent 23-G vitrectomy to confirm the diagnosis using vitreous culture, polymerase chain reaction, and histopathologic examinations. All affected eyes were treated with intravitreal amphotericin B 5 µg/0.1 mL. Fourteen patients received additional systemic antifungal therapy. Diagnostic 23-G vitrectomy confirmed the diagnosis of EFE in 75% of the eyes (12/16). Candida was found to be a causative agent in 62.5% and Aspergillus in 12.5% of the eyes. Retinal detachment was the most common complication (42% of eyes).CONCLUSIONS: EFE can be easily confirmed using primary 23-G vitrectomy.
AB - PURPOSE: To report the outcomes of primary transconjunctival 23-gauge (23-G) vitrectomy in the diagnosis and treatment of presumed endogenous fungal endophthalmitis (EFE).METHODS: Retrospective analysis of patients with EFE who underwent diagnostic transconjunctival 23-G vitrectomy at a tertiary referral center.RESULTS: Nineteen eyes of 15 patients with EFE were included in the study. Four patients had bilateral and 11 patients unilateral disease. Sixteen eyes of 15 patients underwent 23-G vitrectomy to confirm the diagnosis using vitreous culture, polymerase chain reaction, and histopathologic examinations. All affected eyes were treated with intravitreal amphotericin B 5 µg/0.1 mL. Fourteen patients received additional systemic antifungal therapy. Diagnostic 23-G vitrectomy confirmed the diagnosis of EFE in 75% of the eyes (12/16). Candida was found to be a causative agent in 62.5% and Aspergillus in 12.5% of the eyes. Retinal detachment was the most common complication (42% of eyes).CONCLUSIONS: EFE can be easily confirmed using primary 23-G vitrectomy.
U2 - 10.3109/09273948.2015.1115080
DO - 10.3109/09273948.2015.1115080
M3 - SCORING: Journal article
C2 - 26829468
VL - 25
SP - 239
EP - 245
JO - OCUL IMMUNOL INFLAMM
JF - OCUL IMMUNOL INFLAMM
SN - 0927-3948
IS - 2
ER -