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Outcome of in- and out-of-hospital cardiac arrest survivors with liver cirrhosis

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Outcome of in- and out-of-hospital cardiac arrest survivors with liver cirrhosis. / Roedl, Kevin; Wallmüller, Christian; Drolz, Andreas; Horvatits, Thomas; Rutter, Karoline; Spiel, Alexander; Ortbauer, Julia; Stratil, Peter; Hubner, Pia; Weiser, Christoph; Motaabbed, Jasmin Katrin; Jarczak, Dominik; Herkner, Harald; Sterz, Fritz; Fuhrmann, Valentin.

in: ANN INTENSIVE CARE, Jahrgang 7, Nr. 1, 06.10.2017, S. 103.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Roedl, K, Wallmüller, C, Drolz, A, Horvatits, T, Rutter, K, Spiel, A, Ortbauer, J, Stratil, P, Hubner, P, Weiser, C, Motaabbed, JK, Jarczak, D, Herkner, H, Sterz, F & Fuhrmann, V 2017, 'Outcome of in- and out-of-hospital cardiac arrest survivors with liver cirrhosis', ANN INTENSIVE CARE, Jg. 7, Nr. 1, S. 103. https://doi.org/10.1186/s13613-017-0322-1

APA

Roedl, K., Wallmüller, C., Drolz, A., Horvatits, T., Rutter, K., Spiel, A., Ortbauer, J., Stratil, P., Hubner, P., Weiser, C., Motaabbed, J. K., Jarczak, D., Herkner, H., Sterz, F., & Fuhrmann, V. (2017). Outcome of in- and out-of-hospital cardiac arrest survivors with liver cirrhosis. ANN INTENSIVE CARE, 7(1), 103. https://doi.org/10.1186/s13613-017-0322-1

Vancouver

Roedl K, Wallmüller C, Drolz A, Horvatits T, Rutter K, Spiel A et al. Outcome of in- and out-of-hospital cardiac arrest survivors with liver cirrhosis. ANN INTENSIVE CARE. 2017 Okt 6;7(1):103. https://doi.org/10.1186/s13613-017-0322-1

Bibtex

@article{b1575a3f7afb459baba16089dd5ffd79,
title = "Outcome of in- and out-of-hospital cardiac arrest survivors with liver cirrhosis",
abstract = "BACKGROUND: Organ failure increases mortality in patients with liver cirrhosis. Data about resuscitated cardiac arrest patients with liver cirrhosis are missing. This study aims to assess aetiology, survival and functional outcome in patients after successful cardiopulmonary resuscitation (CPR) with and without liver cirrhosis.METHODS: Analysis of prospectively collected cardiac arrest registry data of consecutively hospital-admitted patients following successful CPR was performed. Patient's characteristics, admission diagnosis, severity of disease, course of disease, short- and long-term mortality as well as functional outcome were assessed and compared between patients with and without cirrhosis.RESULTS: Out of 1068 patients with successful CPR, 47 (4%) had liver cirrhosis. Acute-on-chronic liver failure (ACLF) was present in 33 (70%) of these patients on admission, and four patients developed ACLF during follow-up. Mortality at 1 year was more than threefold increased in patients with liver cirrhosis (OR 3.25; 95% CI 1.33-7.96). Liver cirrhosis was associated with impaired neurological outcome (OR for a favourable cerebral performance category: 0.13; 95% CI 0.04-0.36). None of the patients with Child-Turcotte-Pugh (CTP) C cirrhosis survived 28 days with good neurological outcome. Overall nine (19%) patients with cirrhosis survived 28 days with good neurological outcome. All patients with ACLF grade 3 died within 28 days.CONCLUSION: Cardiac arrest survivors with cirrhosis have worse outcome than those without. Although one quarter of patients with liver cirrhosis survived longer than 28 days after successful CPR, patients with CTP C as well as advanced ACLF did not survive 28 days with good neurological outcome.",
keywords = "Journal Article",
author = "Kevin Roedl and Christian Wallm{\"u}ller and Andreas Drolz and Thomas Horvatits and Karoline Rutter and Alexander Spiel and Julia Ortbauer and Peter Stratil and Pia Hubner and Christoph Weiser and Motaabbed, {Jasmin Katrin} and Dominik Jarczak and Harald Herkner and Fritz Sterz and Valentin Fuhrmann",
year = "2017",
month = oct,
day = "6",
doi = "10.1186/s13613-017-0322-1",
language = "English",
volume = "7",
pages = "103",
journal = "ANN INTENSIVE CARE",
issn = "2110-5820",
publisher = "Springer-Verlag GmbH and Co. KG",
number = "1",

}

RIS

TY - JOUR

T1 - Outcome of in- and out-of-hospital cardiac arrest survivors with liver cirrhosis

AU - Roedl, Kevin

AU - Wallmüller, Christian

AU - Drolz, Andreas

AU - Horvatits, Thomas

AU - Rutter, Karoline

AU - Spiel, Alexander

AU - Ortbauer, Julia

AU - Stratil, Peter

AU - Hubner, Pia

AU - Weiser, Christoph

AU - Motaabbed, Jasmin Katrin

AU - Jarczak, Dominik

AU - Herkner, Harald

AU - Sterz, Fritz

AU - Fuhrmann, Valentin

PY - 2017/10/6

Y1 - 2017/10/6

N2 - BACKGROUND: Organ failure increases mortality in patients with liver cirrhosis. Data about resuscitated cardiac arrest patients with liver cirrhosis are missing. This study aims to assess aetiology, survival and functional outcome in patients after successful cardiopulmonary resuscitation (CPR) with and without liver cirrhosis.METHODS: Analysis of prospectively collected cardiac arrest registry data of consecutively hospital-admitted patients following successful CPR was performed. Patient's characteristics, admission diagnosis, severity of disease, course of disease, short- and long-term mortality as well as functional outcome were assessed and compared between patients with and without cirrhosis.RESULTS: Out of 1068 patients with successful CPR, 47 (4%) had liver cirrhosis. Acute-on-chronic liver failure (ACLF) was present in 33 (70%) of these patients on admission, and four patients developed ACLF during follow-up. Mortality at 1 year was more than threefold increased in patients with liver cirrhosis (OR 3.25; 95% CI 1.33-7.96). Liver cirrhosis was associated with impaired neurological outcome (OR for a favourable cerebral performance category: 0.13; 95% CI 0.04-0.36). None of the patients with Child-Turcotte-Pugh (CTP) C cirrhosis survived 28 days with good neurological outcome. Overall nine (19%) patients with cirrhosis survived 28 days with good neurological outcome. All patients with ACLF grade 3 died within 28 days.CONCLUSION: Cardiac arrest survivors with cirrhosis have worse outcome than those without. Although one quarter of patients with liver cirrhosis survived longer than 28 days after successful CPR, patients with CTP C as well as advanced ACLF did not survive 28 days with good neurological outcome.

AB - BACKGROUND: Organ failure increases mortality in patients with liver cirrhosis. Data about resuscitated cardiac arrest patients with liver cirrhosis are missing. This study aims to assess aetiology, survival and functional outcome in patients after successful cardiopulmonary resuscitation (CPR) with and without liver cirrhosis.METHODS: Analysis of prospectively collected cardiac arrest registry data of consecutively hospital-admitted patients following successful CPR was performed. Patient's characteristics, admission diagnosis, severity of disease, course of disease, short- and long-term mortality as well as functional outcome were assessed and compared between patients with and without cirrhosis.RESULTS: Out of 1068 patients with successful CPR, 47 (4%) had liver cirrhosis. Acute-on-chronic liver failure (ACLF) was present in 33 (70%) of these patients on admission, and four patients developed ACLF during follow-up. Mortality at 1 year was more than threefold increased in patients with liver cirrhosis (OR 3.25; 95% CI 1.33-7.96). Liver cirrhosis was associated with impaired neurological outcome (OR for a favourable cerebral performance category: 0.13; 95% CI 0.04-0.36). None of the patients with Child-Turcotte-Pugh (CTP) C cirrhosis survived 28 days with good neurological outcome. Overall nine (19%) patients with cirrhosis survived 28 days with good neurological outcome. All patients with ACLF grade 3 died within 28 days.CONCLUSION: Cardiac arrest survivors with cirrhosis have worse outcome than those without. Although one quarter of patients with liver cirrhosis survived longer than 28 days after successful CPR, patients with CTP C as well as advanced ACLF did not survive 28 days with good neurological outcome.

KW - Journal Article

U2 - 10.1186/s13613-017-0322-1

DO - 10.1186/s13613-017-0322-1

M3 - SCORING: Journal article

C2 - 28986855

VL - 7

SP - 103

JO - ANN INTENSIVE CARE

JF - ANN INTENSIVE CARE

SN - 2110-5820

IS - 1

ER -