Outcome of buccal mucosa graft urethroplasty
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Outcome of buccal mucosa graft urethroplasty : a detailed analysis of success, morbidity and quality of life in a contemporary patient cohort at a referral center. / Soave, Armin; Kluth, Luis; Dahlem, Roland; Rohwer, Amelie; Rink, Michael; Reiss, Philipp; Fisch, Margit; Engel, Oliver.
in: BMC UROL, Jahrgang 19, 18, 18.03.2019.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Outcome of buccal mucosa graft urethroplasty
T2 - a detailed analysis of success, morbidity and quality of life in a contemporary patient cohort at a referral center
AU - Soave, Armin
AU - Kluth, Luis
AU - Dahlem, Roland
AU - Rohwer, Amelie
AU - Rink, Michael
AU - Reiss, Philipp
AU - Fisch, Margit
AU - Engel, Oliver
PY - 2019/3/18
Y1 - 2019/3/18
N2 - BACKGROUND: To evaluate outcome of buccal mucosa graft urethroplasty (BMGU) for the treatment of urethral stricture disease, including a detailed analysis of success, morbidity and quality of life (QoL).METHODS: Between 12/05/2008 and 07/21/2010, 187 patients with urethral stricture disease, who were treated with BMGU at our University Medical Center, received a standardized questionnaire, evaluating postoperative success, morbidity and QoL. The primary endpoint was the success, i.e., stricture recurrence-free survival plus patients' satisfaction with surgery. Secondary endpoints included erectile function, voiding symptoms, pain and health-related QoL, which were assessed with a modified Urethral Stricture Surgery Patient Reported Outcome Measure (USS PROM), including the Erectile Function domain of the International Index of Erectile Function (IIEF-EF), Incontinence Questionnaire Male Lower Urinary Tract Symptoms Module (ICIQ-MLUTS) and EuroQol-5 dimensions (EQ-5D).RESULTS: In total, 83 patients (51.9%) completed the questionnaire. Bulbar, penile and panurethral strictures were found in 69 patients (83.1%), 13 patients (15.7%) and one patient (1.2%), respectively. The median length of the stricture was 5 cm (range: 1-16). At a median follow-up of 46 months (range: 36-54), 65 patients (78.3%) had no stricture recurrence and were satisfied with BMGU. Median scores for ICIQ-MLUTS, IIEF-EF and EQ-5D visual analogue scale were 6, 22 and 80, respectively. Based on USS PROM, postoperative improvement of QoL and satisfaction with BMGU was found in 67 patients (80.7%) and 68 patients (81.9%), respectively.CONCLUSIONS: In patients with urethral stricture disease, BMGU offers excellent success, morbidity and QoL.
AB - BACKGROUND: To evaluate outcome of buccal mucosa graft urethroplasty (BMGU) for the treatment of urethral stricture disease, including a detailed analysis of success, morbidity and quality of life (QoL).METHODS: Between 12/05/2008 and 07/21/2010, 187 patients with urethral stricture disease, who were treated with BMGU at our University Medical Center, received a standardized questionnaire, evaluating postoperative success, morbidity and QoL. The primary endpoint was the success, i.e., stricture recurrence-free survival plus patients' satisfaction with surgery. Secondary endpoints included erectile function, voiding symptoms, pain and health-related QoL, which were assessed with a modified Urethral Stricture Surgery Patient Reported Outcome Measure (USS PROM), including the Erectile Function domain of the International Index of Erectile Function (IIEF-EF), Incontinence Questionnaire Male Lower Urinary Tract Symptoms Module (ICIQ-MLUTS) and EuroQol-5 dimensions (EQ-5D).RESULTS: In total, 83 patients (51.9%) completed the questionnaire. Bulbar, penile and panurethral strictures were found in 69 patients (83.1%), 13 patients (15.7%) and one patient (1.2%), respectively. The median length of the stricture was 5 cm (range: 1-16). At a median follow-up of 46 months (range: 36-54), 65 patients (78.3%) had no stricture recurrence and were satisfied with BMGU. Median scores for ICIQ-MLUTS, IIEF-EF and EQ-5D visual analogue scale were 6, 22 and 80, respectively. Based on USS PROM, postoperative improvement of QoL and satisfaction with BMGU was found in 67 patients (80.7%) and 68 patients (81.9%), respectively.CONCLUSIONS: In patients with urethral stricture disease, BMGU offers excellent success, morbidity and QoL.
KW - Adolescent
KW - Adult
KW - Aged
KW - Cohort Studies
KW - Follow-Up Studies
KW - Humans
KW - Male
KW - Middle Aged
KW - Morbidity
KW - Mouth Mucosa/transplantation
KW - Patient Reported Outcome Measures
KW - Prospective Studies
KW - Quality of Life
KW - Tertiary Care Centers
KW - Treatment Outcome
KW - Urethral Stricture/diagnosis
KW - Urologic Surgical Procedures, Male/methods
KW - Young Adult
U2 - 10.1186/s12894-019-0449-5
DO - 10.1186/s12894-019-0449-5
M3 - SCORING: Journal article
C2 - 30885184
VL - 19
JO - BMC UROL
JF - BMC UROL
SN - 1471-2490
M1 - 18
ER -