Outcome of buccal mucosa graft urethroplasty

Standard

Outcome of buccal mucosa graft urethroplasty : a detailed analysis of success, morbidity and quality of life in a contemporary patient cohort at a referral center. / Soave, Armin; Kluth, Luis; Dahlem, Roland; Rohwer, Amelie; Rink, Michael; Reiss, Philipp; Fisch, Margit; Engel, Oliver.

in: BMC UROL, Jahrgang 19, 18, 18.03.2019.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

Harvard

APA

Vancouver

Bibtex

@article{f907208183a4401ab9340ff2b8ffd116,
title = "Outcome of buccal mucosa graft urethroplasty: a detailed analysis of success, morbidity and quality of life in a contemporary patient cohort at a referral center",
abstract = "BACKGROUND: To evaluate outcome of buccal mucosa graft urethroplasty (BMGU) for the treatment of urethral stricture disease, including a detailed analysis of success, morbidity and quality of life (QoL).METHODS: Between 12/05/2008 and 07/21/2010, 187 patients with urethral stricture disease, who were treated with BMGU at our University Medical Center, received a standardized questionnaire, evaluating postoperative success, morbidity and QoL. The primary endpoint was the success, i.e., stricture recurrence-free survival plus patients' satisfaction with surgery. Secondary endpoints included erectile function, voiding symptoms, pain and health-related QoL, which were assessed with a modified Urethral Stricture Surgery Patient Reported Outcome Measure (USS PROM), including the Erectile Function domain of the International Index of Erectile Function (IIEF-EF), Incontinence Questionnaire Male Lower Urinary Tract Symptoms Module (ICIQ-MLUTS) and EuroQol-5 dimensions (EQ-5D).RESULTS: In total, 83 patients (51.9%) completed the questionnaire. Bulbar, penile and panurethral strictures were found in 69 patients (83.1%), 13 patients (15.7%) and one patient (1.2%), respectively. The median length of the stricture was 5 cm (range: 1-16). At a median follow-up of 46 months (range: 36-54), 65 patients (78.3%) had no stricture recurrence and were satisfied with BMGU. Median scores for ICIQ-MLUTS, IIEF-EF and EQ-5D visual analogue scale were 6, 22 and 80, respectively. Based on USS PROM, postoperative improvement of QoL and satisfaction with BMGU was found in 67 patients (80.7%) and 68 patients (81.9%), respectively.CONCLUSIONS: In patients with urethral stricture disease, BMGU offers excellent success, morbidity and QoL.",
keywords = "Adolescent, Adult, Aged, Cohort Studies, Follow-Up Studies, Humans, Male, Middle Aged, Morbidity, Mouth Mucosa/transplantation, Patient Reported Outcome Measures, Prospective Studies, Quality of Life, Tertiary Care Centers, Treatment Outcome, Urethral Stricture/diagnosis, Urologic Surgical Procedures, Male/methods, Young Adult",
author = "Armin Soave and Luis Kluth and Roland Dahlem and Amelie Rohwer and Michael Rink and Philipp Reiss and Margit Fisch and Oliver Engel",
year = "2019",
month = mar,
day = "18",
doi = "10.1186/s12894-019-0449-5",
language = "English",
volume = "19",
journal = "BMC UROL",
issn = "1471-2490",
publisher = "BioMed Central Ltd.",

}

RIS

TY - JOUR

T1 - Outcome of buccal mucosa graft urethroplasty

T2 - a detailed analysis of success, morbidity and quality of life in a contemporary patient cohort at a referral center

AU - Soave, Armin

AU - Kluth, Luis

AU - Dahlem, Roland

AU - Rohwer, Amelie

AU - Rink, Michael

AU - Reiss, Philipp

AU - Fisch, Margit

AU - Engel, Oliver

PY - 2019/3/18

Y1 - 2019/3/18

N2 - BACKGROUND: To evaluate outcome of buccal mucosa graft urethroplasty (BMGU) for the treatment of urethral stricture disease, including a detailed analysis of success, morbidity and quality of life (QoL).METHODS: Between 12/05/2008 and 07/21/2010, 187 patients with urethral stricture disease, who were treated with BMGU at our University Medical Center, received a standardized questionnaire, evaluating postoperative success, morbidity and QoL. The primary endpoint was the success, i.e., stricture recurrence-free survival plus patients' satisfaction with surgery. Secondary endpoints included erectile function, voiding symptoms, pain and health-related QoL, which were assessed with a modified Urethral Stricture Surgery Patient Reported Outcome Measure (USS PROM), including the Erectile Function domain of the International Index of Erectile Function (IIEF-EF), Incontinence Questionnaire Male Lower Urinary Tract Symptoms Module (ICIQ-MLUTS) and EuroQol-5 dimensions (EQ-5D).RESULTS: In total, 83 patients (51.9%) completed the questionnaire. Bulbar, penile and panurethral strictures were found in 69 patients (83.1%), 13 patients (15.7%) and one patient (1.2%), respectively. The median length of the stricture was 5 cm (range: 1-16). At a median follow-up of 46 months (range: 36-54), 65 patients (78.3%) had no stricture recurrence and were satisfied with BMGU. Median scores for ICIQ-MLUTS, IIEF-EF and EQ-5D visual analogue scale were 6, 22 and 80, respectively. Based on USS PROM, postoperative improvement of QoL and satisfaction with BMGU was found in 67 patients (80.7%) and 68 patients (81.9%), respectively.CONCLUSIONS: In patients with urethral stricture disease, BMGU offers excellent success, morbidity and QoL.

AB - BACKGROUND: To evaluate outcome of buccal mucosa graft urethroplasty (BMGU) for the treatment of urethral stricture disease, including a detailed analysis of success, morbidity and quality of life (QoL).METHODS: Between 12/05/2008 and 07/21/2010, 187 patients with urethral stricture disease, who were treated with BMGU at our University Medical Center, received a standardized questionnaire, evaluating postoperative success, morbidity and QoL. The primary endpoint was the success, i.e., stricture recurrence-free survival plus patients' satisfaction with surgery. Secondary endpoints included erectile function, voiding symptoms, pain and health-related QoL, which were assessed with a modified Urethral Stricture Surgery Patient Reported Outcome Measure (USS PROM), including the Erectile Function domain of the International Index of Erectile Function (IIEF-EF), Incontinence Questionnaire Male Lower Urinary Tract Symptoms Module (ICIQ-MLUTS) and EuroQol-5 dimensions (EQ-5D).RESULTS: In total, 83 patients (51.9%) completed the questionnaire. Bulbar, penile and panurethral strictures were found in 69 patients (83.1%), 13 patients (15.7%) and one patient (1.2%), respectively. The median length of the stricture was 5 cm (range: 1-16). At a median follow-up of 46 months (range: 36-54), 65 patients (78.3%) had no stricture recurrence and were satisfied with BMGU. Median scores for ICIQ-MLUTS, IIEF-EF and EQ-5D visual analogue scale were 6, 22 and 80, respectively. Based on USS PROM, postoperative improvement of QoL and satisfaction with BMGU was found in 67 patients (80.7%) and 68 patients (81.9%), respectively.CONCLUSIONS: In patients with urethral stricture disease, BMGU offers excellent success, morbidity and QoL.

KW - Adolescent

KW - Adult

KW - Aged

KW - Cohort Studies

KW - Follow-Up Studies

KW - Humans

KW - Male

KW - Middle Aged

KW - Morbidity

KW - Mouth Mucosa/transplantation

KW - Patient Reported Outcome Measures

KW - Prospective Studies

KW - Quality of Life

KW - Tertiary Care Centers

KW - Treatment Outcome

KW - Urethral Stricture/diagnosis

KW - Urologic Surgical Procedures, Male/methods

KW - Young Adult

U2 - 10.1186/s12894-019-0449-5

DO - 10.1186/s12894-019-0449-5

M3 - SCORING: Journal article

C2 - 30885184

VL - 19

JO - BMC UROL

JF - BMC UROL

SN - 1471-2490

M1 - 18

ER -