Outbreak of systemic aspergillosis in a neonatal intensive care unit.
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Outbreak of systemic aspergillosis in a neonatal intensive care unit. / Singer, S; Singer, Dominique; Rüchel, R; Mergeryan, H; Schmidt, U; Harms, K.
in: MYCOSES, Jahrgang 41, Nr. 5-6, 5-6, 1998, S. 223-227.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Outbreak of systemic aspergillosis in a neonatal intensive care unit.
AU - Singer, S
AU - Singer, Dominique
AU - Rüchel, R
AU - Mergeryan, H
AU - Schmidt, U
AU - Harms, K
PY - 1998
Y1 - 1998
N2 - Small pre-term neonates are susceptible to cutaneous aspergillosis because of their immature immune system and because of the vulnerability of their skin. In addition, the common therapy with broad-spectrum antibiotic drugs and corticoids creates a favourable milieu for fungal superinfections. We present four pre-term neonates who succumbed to cutaneous aspergillosis that subsequently developed into a systemic infection. The source of the infection proved to be contaminated latex finger stalls. Three of the four patients died. The poor prognosis for systemic aspergillosis can only be improved by an early therapy with amphotericin B, possibly in liposomal form.
AB - Small pre-term neonates are susceptible to cutaneous aspergillosis because of their immature immune system and because of the vulnerability of their skin. In addition, the common therapy with broad-spectrum antibiotic drugs and corticoids creates a favourable milieu for fungal superinfections. We present four pre-term neonates who succumbed to cutaneous aspergillosis that subsequently developed into a systemic infection. The source of the infection proved to be contaminated latex finger stalls. Three of the four patients died. The poor prognosis for systemic aspergillosis can only be improved by an early therapy with amphotericin B, possibly in liposomal form.
M3 - SCORING: Zeitschriftenaufsatz
VL - 41
SP - 223
EP - 227
JO - MYCOSES
JF - MYCOSES
SN - 0933-7407
IS - 5-6
M1 - 5-6
ER -