Oral mature teratoma containing epididymal tissue in a female neonate.
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Oral mature teratoma containing epididymal tissue in a female neonate. / Beutel, Karin; Partsch, C J; Jänig, U; Nikischin, W; Suttorp, M.
in: LANCET, Jahrgang 357, Nr. 9252, 9252, 2001, S. 283-284.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Oral mature teratoma containing epididymal tissue in a female neonate.
AU - Beutel, Karin
AU - Partsch, C J
AU - Jänig, U
AU - Nikischin, W
AU - Suttorp, M
PY - 2001
Y1 - 2001
N2 - We describe a female neonate with an oral teratoma showing bone, teeth, and epidermis, but also epididymal (male) tissue. PCR amplification of Y-chromosomal DNA clearly showed male DNA from paraffin-embedded tumour tissue. The girl had a normal female karyotype without abnormalities of the genital organs. There are at least three hypotheses for the origin of teratomas: parthenogenesis, incomplete twinning, and totipotent somatic-cell origin. This case supports the hypothesis of an included dizygotic twin, and might contribute to the elucidation of the pathogenesis of extragonadal teratomas.
AB - We describe a female neonate with an oral teratoma showing bone, teeth, and epidermis, but also epididymal (male) tissue. PCR amplification of Y-chromosomal DNA clearly showed male DNA from paraffin-embedded tumour tissue. The girl had a normal female karyotype without abnormalities of the genital organs. There are at least three hypotheses for the origin of teratomas: parthenogenesis, incomplete twinning, and totipotent somatic-cell origin. This case supports the hypothesis of an included dizygotic twin, and might contribute to the elucidation of the pathogenesis of extragonadal teratomas.
M3 - SCORING: Zeitschriftenaufsatz
VL - 357
SP - 283
EP - 284
JO - LANCET
JF - LANCET
SN - 0140-6736
IS - 9252
M1 - 9252
ER -
