Optical coherence tomography for tissue classification of the larynx in an outpatient setting-a translational challenge on the verge of a resolution?

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Optical coherence tomography for tissue classification of the larynx in an outpatient setting-a translational challenge on the verge of a resolution? / Wittig, Lukas; Betz, Christian; Eggert, Dennis.

in: Translational Biophotonics, Jahrgang n/a, Nr. n/a, 2020, S. e202000013.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ReviewForschung

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Bibtex

@article{ad317c2dcb054ece864ac83b98016155,
title = "Optical coherence tomography for tissue classification of the larynx in an outpatient setting-a translational challenge on the verge of a resolution?",
abstract = "Abstract The detection and tissue classification of mucosal lesions of the upper aerodigestive tract (UADT) is crucial for the development of a treatment plan. Using modern endoscopic examination techniques mucosal changes can be detected early on in an office-based setting. However, the further classification of these lesions requires a surgical procedure with a biopsy taken under general anesthesia. Optical coherence tomography (OCT) is a noninvasive, light-based optical tool which can provide high-resolution cross-sectional images of tissue at near microscopic resolution. Applying it through a single mode optical fiber allows endoscopic approaches. Routine endoscopic assessment and a thin epithelial layer makes the larynx the perfect organ for implementing OCT into the clinical endoscopic routine. This review is focused on summarizing previous and ongoing translational applications of OCT imaging for tissue classification in the UADT focusing on the larynx, discussing limitations and benefits and offering an outlook on possible future applications.",
keywords = "cancer, deep learning, larynx, mucosal lesion, optical coherence tomography, upper aerodigestive tract",
author = "Lukas Wittig and Christian Betz and Dennis Eggert",
note = "https://doi.org/10.1002/tbio.202000013",
year = "2020",
doi = "10.1002/tbio.202000013",
language = "Deutsch",
volume = "n/a",
pages = "e202000013",
number = "n/a",

}

RIS

TY - JOUR

T1 - Optical coherence tomography for tissue classification of the larynx in an outpatient setting-a translational challenge on the verge of a resolution?

AU - Wittig, Lukas

AU - Betz, Christian

AU - Eggert, Dennis

N1 - https://doi.org/10.1002/tbio.202000013

PY - 2020

Y1 - 2020

N2 - Abstract The detection and tissue classification of mucosal lesions of the upper aerodigestive tract (UADT) is crucial for the development of a treatment plan. Using modern endoscopic examination techniques mucosal changes can be detected early on in an office-based setting. However, the further classification of these lesions requires a surgical procedure with a biopsy taken under general anesthesia. Optical coherence tomography (OCT) is a noninvasive, light-based optical tool which can provide high-resolution cross-sectional images of tissue at near microscopic resolution. Applying it through a single mode optical fiber allows endoscopic approaches. Routine endoscopic assessment and a thin epithelial layer makes the larynx the perfect organ for implementing OCT into the clinical endoscopic routine. This review is focused on summarizing previous and ongoing translational applications of OCT imaging for tissue classification in the UADT focusing on the larynx, discussing limitations and benefits and offering an outlook on possible future applications.

AB - Abstract The detection and tissue classification of mucosal lesions of the upper aerodigestive tract (UADT) is crucial for the development of a treatment plan. Using modern endoscopic examination techniques mucosal changes can be detected early on in an office-based setting. However, the further classification of these lesions requires a surgical procedure with a biopsy taken under general anesthesia. Optical coherence tomography (OCT) is a noninvasive, light-based optical tool which can provide high-resolution cross-sectional images of tissue at near microscopic resolution. Applying it through a single mode optical fiber allows endoscopic approaches. Routine endoscopic assessment and a thin epithelial layer makes the larynx the perfect organ for implementing OCT into the clinical endoscopic routine. This review is focused on summarizing previous and ongoing translational applications of OCT imaging for tissue classification in the UADT focusing on the larynx, discussing limitations and benefits and offering an outlook on possible future applications.

KW - cancer

KW - deep learning

KW - larynx

KW - mucosal lesion

KW - optical coherence tomography

KW - upper aerodigestive tract

U2 - 10.1002/tbio.202000013

DO - 10.1002/tbio.202000013

M3 - SCORING: Review

VL - n/a

SP - e202000013

IS - n/a

ER -