Opinion: Challenges in circulating tumour cell research

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Opinion: Challenges in circulating tumour cell research. / Alix-Panabières, Catherine; Pantel, Klaus.

in: NAT REV CANCER, Jahrgang 14, Nr. 9, 01.09.2014, S. 623-631.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

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@article{1f2e40d529494eeeb6228ae731bfc743,
title = "Opinion: Challenges in circulating tumour cell research",
abstract = "During the past ten years, circulating tumour cells (CTCs) have received enormous attention as new biomarkers and the subject of basic research. Although CTCs are already used in numerous clinical trials, their clinical utility is still under investigation. Many issues regarding the detection and characterization of CTCs remain unknown. In this Opinion article, we propose a conceptual framework of CTC assays and point out current challenges of CTC research, which might structure this dynamic field of translational cancer research.",
keywords = "Humans, Neoplasm Proteins, Neoplastic Cells, Circulating, Tumor Markers, Biological",
author = "Catherine Alix-Panabi{\`e}res and Klaus Pantel",
year = "2014",
month = sep,
day = "1",
doi = "10.1038/nrc3820",
language = "English",
volume = "14",
pages = "623--631",
journal = "NAT REV CANCER",
issn = "1474-175X",
publisher = "NATURE PUBLISHING GROUP",
number = "9",

}

RIS

TY - JOUR

T1 - Opinion: Challenges in circulating tumour cell research

AU - Alix-Panabières, Catherine

AU - Pantel, Klaus

PY - 2014/9/1

Y1 - 2014/9/1

N2 - During the past ten years, circulating tumour cells (CTCs) have received enormous attention as new biomarkers and the subject of basic research. Although CTCs are already used in numerous clinical trials, their clinical utility is still under investigation. Many issues regarding the detection and characterization of CTCs remain unknown. In this Opinion article, we propose a conceptual framework of CTC assays and point out current challenges of CTC research, which might structure this dynamic field of translational cancer research.

AB - During the past ten years, circulating tumour cells (CTCs) have received enormous attention as new biomarkers and the subject of basic research. Although CTCs are already used in numerous clinical trials, their clinical utility is still under investigation. Many issues regarding the detection and characterization of CTCs remain unknown. In this Opinion article, we propose a conceptual framework of CTC assays and point out current challenges of CTC research, which might structure this dynamic field of translational cancer research.

KW - Humans

KW - Neoplasm Proteins

KW - Neoplastic Cells, Circulating

KW - Tumor Markers, Biological

U2 - 10.1038/nrc3820

DO - 10.1038/nrc3820

M3 - SCORING: Journal article

C2 - 25154812

VL - 14

SP - 623

EP - 631

JO - NAT REV CANCER

JF - NAT REV CANCER

SN - 1474-175X

IS - 9

ER -