Opiate pharmacology and individual differences. II. Somatosensory evoked potentials.
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Opiate pharmacology and individual differences. II. Somatosensory evoked potentials. / Buchsbaum, M S; Davis, G C; Coppola, R; Naber, Dieter.
in: PAIN, Jahrgang 10, Nr. 3, 3, 1981, S. 367-377.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Opiate pharmacology and individual differences. II. Somatosensory evoked potentials.
AU - Buchsbaum, M S
AU - Davis, G C
AU - Coppola, R
AU - Naber, Dieter
PY - 1981
Y1 - 1981
N2 - Somatosensory evoked potentials (EPs) to stimuli ranging from barely perceptible to painful were recorded in 153 normal adults. Reliability of amplitude and amplitude/intensity slopes were demonstrated in 29 individuals tested twice, two or more weeks apart. In randomized, double-blind placebo controlled trials, both aspirin and morphine significantly diminished N120 component at high stimulus intensities. Age, sex and pharmacological effects paralleled those found with psychophysical techniques in part I of this study.
AB - Somatosensory evoked potentials (EPs) to stimuli ranging from barely perceptible to painful were recorded in 153 normal adults. Reliability of amplitude and amplitude/intensity slopes were demonstrated in 29 individuals tested twice, two or more weeks apart. In randomized, double-blind placebo controlled trials, both aspirin and morphine significantly diminished N120 component at high stimulus intensities. Age, sex and pharmacological effects paralleled those found with psychophysical techniques in part I of this study.
M3 - SCORING: Zeitschriftenaufsatz
VL - 10
SP - 367
EP - 377
JO - PAIN
JF - PAIN
SN - 0304-3959
IS - 3
M1 - 3
ER -