Open-access quantitative MRI data of the spinal cord and reproducibility across participants, sites and manufacturers
Beteiligte Einrichtungen
Abstract
In a companion paper by Cohen-Adad et al. we introduce the spine generic quantitative MRI protocol that provides valuable metrics for assessing spinal cord macrostructural and microstructural integrity. This protocol was used to acquire a single subject dataset across 19 centers and a multi-subject dataset across 42 centers (for a total of 260 participants), spanning the three main MRI manufacturers: GE, Philips and Siemens. Both datasets are publicly available via git-annex. Data were analysed using the Spinal Cord Toolbox to produce normative values as well as inter/intra-site and inter/intra-manufacturer statistics. Reproducibility for the spine generic protocol was high across sites and manufacturers, with an average inter-site coefficient of variation of less than 5% for all the metrics. Full documentation and results can be found at https://spine-generic.rtfd.io/ . The datasets and analysis pipeline will help pave the way towards accessible and reproducible quantitative MRI in the spinal cord.
Bibliografische Daten
Originalsprache | Englisch |
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Aufsatznummer | 219 |
ISSN | 2052-4463 |
DOIs | |
Status | Veröffentlicht - 16.08.2021 |
Anmerkungen des Dekanats
© 2021. The Author(s).
PubMed | 34400655 |
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