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Olfactory dysfunction in patients with idiopathic intracranial hypertension

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Olfactory dysfunction in patients with idiopathic intracranial hypertension. / Kunte, Hagen; Schmidt, Felix; Kronenberg, Golo; Hoffmann, Jan; Schmidt, Christoph; Harms, Lutz; Goektas, Onder.

in: NEUROLOGY, Jahrgang 81, Nr. 4, 23.07.2013, S. 379-82.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Kunte, H, Schmidt, F, Kronenberg, G, Hoffmann, J, Schmidt, C, Harms, L & Goektas, O 2013, 'Olfactory dysfunction in patients with idiopathic intracranial hypertension', NEUROLOGY, Jg. 81, Nr. 4, S. 379-82. https://doi.org/10.1212/WNL.0b013e31829c5c9d

APA

Kunte, H., Schmidt, F., Kronenberg, G., Hoffmann, J., Schmidt, C., Harms, L., & Goektas, O. (2013). Olfactory dysfunction in patients with idiopathic intracranial hypertension. NEUROLOGY, 81(4), 379-82. https://doi.org/10.1212/WNL.0b013e31829c5c9d

Vancouver

Kunte H, Schmidt F, Kronenberg G, Hoffmann J, Schmidt C, Harms L et al. Olfactory dysfunction in patients with idiopathic intracranial hypertension. NEUROLOGY. 2013 Jul 23;81(4):379-82. https://doi.org/10.1212/WNL.0b013e31829c5c9d

Bibtex

@article{4a33a56e65874a7caa80484106979b04,
title = "Olfactory dysfunction in patients with idiopathic intracranial hypertension",
abstract = "OBJECTIVE: Although accumulating evidence suggests that a malfunction of the CSF system in idiopathic intracranial hypertension (IIH) may give rise to olfactory dysfunction, little objective knowledge is available at present about the olfactory capacity of patients with this condition.METHODS: Seventeen patients with IIH and 17 age- and sex-matched controls were included. The extended Sniffin' Sticks procedure was used to test odor threshold, discrimination, and identification (TDI).RESULTS: Median (interquartile range) values of the composite TDI score (29 [26.5-35.5] vs 35 [34-37], p = 0.003) were reduced in patients with IIH. Furthermore, Spearman correlation revealed reduced TDI values in patients with a recent clinical deterioration of IIH (r = 0.66, p = 0.004).CONCLUSIONS: Our pilot study provides new evidence that olfaction is impaired in patients with IIH, especially in those who have been newly diagnosed or who have experienced a recent clinical deterioration.",
keywords = "Adult, Case-Control Studies, Chi-Square Distribution, Female, Humans, Male, Odorants, Olfaction Disorders, Pseudotumor Cerebri, Smell, Journal Article",
author = "Hagen Kunte and Felix Schmidt and Golo Kronenberg and Jan Hoffmann and Christoph Schmidt and Lutz Harms and Onder Goektas",
year = "2013",
month = jul,
day = "23",
doi = "10.1212/WNL.0b013e31829c5c9d",
language = "English",
volume = "81",
pages = "379--82",
journal = "NEUROLOGY",
issn = "0028-3878",
publisher = "Lippincott Williams and Wilkins",
number = "4",

}

RIS

TY - JOUR

T1 - Olfactory dysfunction in patients with idiopathic intracranial hypertension

AU - Kunte, Hagen

AU - Schmidt, Felix

AU - Kronenberg, Golo

AU - Hoffmann, Jan

AU - Schmidt, Christoph

AU - Harms, Lutz

AU - Goektas, Onder

PY - 2013/7/23

Y1 - 2013/7/23

N2 - OBJECTIVE: Although accumulating evidence suggests that a malfunction of the CSF system in idiopathic intracranial hypertension (IIH) may give rise to olfactory dysfunction, little objective knowledge is available at present about the olfactory capacity of patients with this condition.METHODS: Seventeen patients with IIH and 17 age- and sex-matched controls were included. The extended Sniffin' Sticks procedure was used to test odor threshold, discrimination, and identification (TDI).RESULTS: Median (interquartile range) values of the composite TDI score (29 [26.5-35.5] vs 35 [34-37], p = 0.003) were reduced in patients with IIH. Furthermore, Spearman correlation revealed reduced TDI values in patients with a recent clinical deterioration of IIH (r = 0.66, p = 0.004).CONCLUSIONS: Our pilot study provides new evidence that olfaction is impaired in patients with IIH, especially in those who have been newly diagnosed or who have experienced a recent clinical deterioration.

AB - OBJECTIVE: Although accumulating evidence suggests that a malfunction of the CSF system in idiopathic intracranial hypertension (IIH) may give rise to olfactory dysfunction, little objective knowledge is available at present about the olfactory capacity of patients with this condition.METHODS: Seventeen patients with IIH and 17 age- and sex-matched controls were included. The extended Sniffin' Sticks procedure was used to test odor threshold, discrimination, and identification (TDI).RESULTS: Median (interquartile range) values of the composite TDI score (29 [26.5-35.5] vs 35 [34-37], p = 0.003) were reduced in patients with IIH. Furthermore, Spearman correlation revealed reduced TDI values in patients with a recent clinical deterioration of IIH (r = 0.66, p = 0.004).CONCLUSIONS: Our pilot study provides new evidence that olfaction is impaired in patients with IIH, especially in those who have been newly diagnosed or who have experienced a recent clinical deterioration.

KW - Adult

KW - Case-Control Studies

KW - Chi-Square Distribution

KW - Female

KW - Humans

KW - Male

KW - Odorants

KW - Olfaction Disorders

KW - Pseudotumor Cerebri

KW - Smell

KW - Journal Article

U2 - 10.1212/WNL.0b013e31829c5c9d

DO - 10.1212/WNL.0b013e31829c5c9d

M3 - SCORING: Journal article

C2 - 23794685

VL - 81

SP - 379

EP - 382

JO - NEUROLOGY

JF - NEUROLOGY

SN - 0028-3878

IS - 4

ER -