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Of guinea pigs and men--an unusual case of jaundice.

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Of guinea pigs and men--an unusual case of jaundice. / Pischke, S; Ehmer, U; Schedel, I; Gratz, W F; Wedemeyer, H; Ziesing, S; Bange, F C; Burchard, Gerd-Dieter; Manns, M P; Bahr, M J; Strassburg, C P.

in: Z GASTROENTEROL, Jahrgang 48, Nr. 1, 1, 2010, S. 33-37.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung

Harvard

Pischke, S, Ehmer, U, Schedel, I, Gratz, WF, Wedemeyer, H, Ziesing, S, Bange, FC, Burchard, G-D, Manns, MP, Bahr, MJ & Strassburg, CP 2010, 'Of guinea pigs and men--an unusual case of jaundice.', Z GASTROENTEROL, Jg. 48, Nr. 1, 1, S. 33-37. <http://www.ncbi.nlm.nih.gov/pubmed/20072994?dopt=Citation>

APA

Pischke, S., Ehmer, U., Schedel, I., Gratz, W. F., Wedemeyer, H., Ziesing, S., Bange, F. C., Burchard, G-D., Manns, M. P., Bahr, M. J., & Strassburg, C. P. (2010). Of guinea pigs and men--an unusual case of jaundice. Z GASTROENTEROL, 48(1), 33-37. [1]. http://www.ncbi.nlm.nih.gov/pubmed/20072994?dopt=Citation

Vancouver

Pischke S, Ehmer U, Schedel I, Gratz WF, Wedemeyer H, Ziesing S et al. Of guinea pigs and men--an unusual case of jaundice. Z GASTROENTEROL. 2010;48(1):33-37. 1.

Bibtex

@article{ccb382b920b741859b566731fb0ebe09,
title = "Of guinea pigs and men--an unusual case of jaundice.",
abstract = "A 21-year-old male presented at the emergency room with jaundice, itching, dry cough, malaise and weight loss of 10 kg during the preceding four weeks. Eighteen months earlier, the patient had suffered an automobile accident leading to polytrauma. Serological markers for viral or other causes of hepatitis were absent. For suspected secondary sclerosing cholangitis, ultrasound and ERCP were performed but failed to reveal pathological findings. A liver biopsy showed cholestatic liver disease without signs of portal field-associated hepatitis. Hepato-biliary scintigraphy demonstrated hepatocellular dysfunction. The patient finally mentioned his guinea pig farm with around 50 animals, 20 of which had recently died for unknown reasons. The patient and three of his guinea pigs were subsequently tested for serological evidence of leptospirosis. IgG and IgM antibodies reacting with Leptospira interrogans were detected in the patient's serum, and all 3 guinea pigs were serologically positive for serovar Bratislava. Bacterial culture was not successful, and also PCR tests remained negative. The clinical symptoms quickly resolved after the initiation of antibiotic therapy with amoxicillin.",
keywords = "Animals, Diagnosis, Differential, Humans, Male, Young Adult, Immunoglobulin G blood, Agricultural Workers' Diseases diagnosis, Animal Husbandry, Guinea Pigs, Immunoglobulin M blood, Jaundice, Obstructive diagnosis, Leptospira interrogans immunology, Leptospirosis diagnosis, Microbiology, Rodent Diseases diagnosis, Zoonoses microbiology, Animals, Diagnosis, Differential, Humans, Male, Young Adult, Immunoglobulin G blood, Agricultural Workers' Diseases diagnosis, Animal Husbandry, Guinea Pigs, Immunoglobulin M blood, Jaundice, Obstructive diagnosis, Leptospira interrogans immunology, Leptospirosis diagnosis, Microbiology, Rodent Diseases diagnosis, Zoonoses microbiology",
author = "S Pischke and U Ehmer and I Schedel and Gratz, {W F} and H Wedemeyer and S Ziesing and Bange, {F C} and Gerd-Dieter Burchard and Manns, {M P} and Bahr, {M J} and Strassburg, {C P}",
year = "2010",
language = "Deutsch",
volume = "48",
pages = "33--37",
journal = "Z GASTROENTEROL",
issn = "0044-2771",
publisher = "Karl Demeter Verlag GmbH",
number = "1",

}

RIS

TY - JOUR

T1 - Of guinea pigs and men--an unusual case of jaundice.

AU - Pischke, S

AU - Ehmer, U

AU - Schedel, I

AU - Gratz, W F

AU - Wedemeyer, H

AU - Ziesing, S

AU - Bange, F C

AU - Burchard, Gerd-Dieter

AU - Manns, M P

AU - Bahr, M J

AU - Strassburg, C P

PY - 2010

Y1 - 2010

N2 - A 21-year-old male presented at the emergency room with jaundice, itching, dry cough, malaise and weight loss of 10 kg during the preceding four weeks. Eighteen months earlier, the patient had suffered an automobile accident leading to polytrauma. Serological markers for viral or other causes of hepatitis were absent. For suspected secondary sclerosing cholangitis, ultrasound and ERCP were performed but failed to reveal pathological findings. A liver biopsy showed cholestatic liver disease without signs of portal field-associated hepatitis. Hepato-biliary scintigraphy demonstrated hepatocellular dysfunction. The patient finally mentioned his guinea pig farm with around 50 animals, 20 of which had recently died for unknown reasons. The patient and three of his guinea pigs were subsequently tested for serological evidence of leptospirosis. IgG and IgM antibodies reacting with Leptospira interrogans were detected in the patient's serum, and all 3 guinea pigs were serologically positive for serovar Bratislava. Bacterial culture was not successful, and also PCR tests remained negative. The clinical symptoms quickly resolved after the initiation of antibiotic therapy with amoxicillin.

AB - A 21-year-old male presented at the emergency room with jaundice, itching, dry cough, malaise and weight loss of 10 kg during the preceding four weeks. Eighteen months earlier, the patient had suffered an automobile accident leading to polytrauma. Serological markers for viral or other causes of hepatitis were absent. For suspected secondary sclerosing cholangitis, ultrasound and ERCP were performed but failed to reveal pathological findings. A liver biopsy showed cholestatic liver disease without signs of portal field-associated hepatitis. Hepato-biliary scintigraphy demonstrated hepatocellular dysfunction. The patient finally mentioned his guinea pig farm with around 50 animals, 20 of which had recently died for unknown reasons. The patient and three of his guinea pigs were subsequently tested for serological evidence of leptospirosis. IgG and IgM antibodies reacting with Leptospira interrogans were detected in the patient's serum, and all 3 guinea pigs were serologically positive for serovar Bratislava. Bacterial culture was not successful, and also PCR tests remained negative. The clinical symptoms quickly resolved after the initiation of antibiotic therapy with amoxicillin.

KW - Animals

KW - Diagnosis, Differential

KW - Humans

KW - Male

KW - Young Adult

KW - Immunoglobulin G blood

KW - Agricultural Workers' Diseases diagnosis

KW - Animal Husbandry

KW - Guinea Pigs

KW - Immunoglobulin M blood

KW - Jaundice, Obstructive diagnosis

KW - Leptospira interrogans immunology

KW - Leptospirosis diagnosis

KW - Microbiology

KW - Rodent Diseases diagnosis

KW - Zoonoses microbiology

KW - Animals

KW - Diagnosis, Differential

KW - Humans

KW - Male

KW - Young Adult

KW - Immunoglobulin G blood

KW - Agricultural Workers' Diseases diagnosis

KW - Animal Husbandry

KW - Guinea Pigs

KW - Immunoglobulin M blood

KW - Jaundice, Obstructive diagnosis

KW - Leptospira interrogans immunology

KW - Leptospirosis diagnosis

KW - Microbiology

KW - Rodent Diseases diagnosis

KW - Zoonoses microbiology

M3 - SCORING: Zeitschriftenaufsatz

VL - 48

SP - 33

EP - 37

JO - Z GASTROENTEROL

JF - Z GASTROENTEROL

SN - 0044-2771

IS - 1

M1 - 1

ER -