Ocular dominance in extrastriate cortex of strabismic amblyopic cats
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Ocular dominance in extrastriate cortex of strabismic amblyopic cats. / Schröder, Jan-Hinrich; Fries, Pascal; Roelfsema, Pieter R; Singer, Wolf; Engel, Andreas K.
in: VISION RES, Jahrgang 42, Nr. 1, 01.01.2002, S. 29-39.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Ocular dominance in extrastriate cortex of strabismic amblyopic cats
AU - Schröder, Jan-Hinrich
AU - Fries, Pascal
AU - Roelfsema, Pieter R
AU - Singer, Wolf
AU - Engel, Andreas K
PY - 2002/1/1
Y1 - 2002/1/1
N2 - Ocular dominance in extrastriate visual cortex of cats with behaviorally defined strabismic amblyopia was studied using extracellular recording techniques. In area 18, the amblyopic eye drove about as many cells as the normal one. In area posteromedial lateral suprasylvian area (PMLS), about 60% of the cells responded exclusively to stimulation of the normal eye and 30% to stimulation of the amblyopic eye. In area 21a more than 75% of the cells were monocularly driven by the non-amblyopic eye while only 5% were monocularly driven by the amblyopic eye. These findings suggest that ventral pathways (area 21a) are more affected in amblyopia than dorsal pathways (area PMLS).
AB - Ocular dominance in extrastriate visual cortex of cats with behaviorally defined strabismic amblyopia was studied using extracellular recording techniques. In area 18, the amblyopic eye drove about as many cells as the normal one. In area posteromedial lateral suprasylvian area (PMLS), about 60% of the cells responded exclusively to stimulation of the normal eye and 30% to stimulation of the amblyopic eye. In area 21a more than 75% of the cells were monocularly driven by the non-amblyopic eye while only 5% were monocularly driven by the amblyopic eye. These findings suggest that ventral pathways (area 21a) are more affected in amblyopia than dorsal pathways (area PMLS).
KW - Amblyopia
KW - Animals
KW - Binomial Distribution
KW - Cats
KW - Confidence Intervals
KW - Discrimination (Psychology)
KW - Dominance, Cerebral
KW - Microelectrodes
KW - Monte Carlo Method
KW - Psychometrics
KW - Strabismus
KW - Visual Cortex
M3 - SCORING: Journal article
C2 - 11804629
VL - 42
SP - 29
EP - 39
JO - VISION RES
JF - VISION RES
SN - 0042-6989
IS - 1
ER -