Novelty-induced behavioral traits correlate with numbers of brainstem noradrenergic neurons and septal cholinergic neurons in C57BL/6J mice.

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Novelty-induced behavioral traits correlate with numbers of brainstem noradrenergic neurons and septal cholinergic neurons in C57BL/6J mice. / Tereshchenko, Yuliya; Brandewiede, Jörg; Schachner, Melitta; Irintchev, Andrey; Morellini, Fabio.

in: BEHAV BRAIN RES, Jahrgang 191, Nr. 2, 2, 2008, S. 280-284.

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@article{fabce9cada3c4cfeaab1711b57929bf7,
title = "Novelty-induced behavioral traits correlate with numbers of brainstem noradrenergic neurons and septal cholinergic neurons in C57BL/6J mice.",
abstract = "It is generally accepted that different brain regions regulate specific behavioral responses and that structural alterations in these regions may affect behavior. We investigated whether inter-individual variability in novelty-induced behaviors in C57BL/6J mice correlates with numbers of noradrenergic neurons in the locus coeruleus and cholinergic neurons in the septum. We found that exploration of new stimuli correlated negatively with numbers of noradrenergic neurons, whereas anxiety correlated positively with numbers of cholinergic neurons. The observed correlations suggest physiologically plausible links between structure and function and indicate that precise morphological estimates can be predictive for behavioral responses.",
author = "Yuliya Tereshchenko and J{\"o}rg Brandewiede and Melitta Schachner and Andrey Irintchev and Fabio Morellini",
year = "2008",
language = "Deutsch",
volume = "191",
pages = "280--284",
journal = "BEHAV BRAIN RES",
issn = "0166-4328",
publisher = "Elsevier",
number = "2",

}

RIS

TY - JOUR

T1 - Novelty-induced behavioral traits correlate with numbers of brainstem noradrenergic neurons and septal cholinergic neurons in C57BL/6J mice.

AU - Tereshchenko, Yuliya

AU - Brandewiede, Jörg

AU - Schachner, Melitta

AU - Irintchev, Andrey

AU - Morellini, Fabio

PY - 2008

Y1 - 2008

N2 - It is generally accepted that different brain regions regulate specific behavioral responses and that structural alterations in these regions may affect behavior. We investigated whether inter-individual variability in novelty-induced behaviors in C57BL/6J mice correlates with numbers of noradrenergic neurons in the locus coeruleus and cholinergic neurons in the septum. We found that exploration of new stimuli correlated negatively with numbers of noradrenergic neurons, whereas anxiety correlated positively with numbers of cholinergic neurons. The observed correlations suggest physiologically plausible links between structure and function and indicate that precise morphological estimates can be predictive for behavioral responses.

AB - It is generally accepted that different brain regions regulate specific behavioral responses and that structural alterations in these regions may affect behavior. We investigated whether inter-individual variability in novelty-induced behaviors in C57BL/6J mice correlates with numbers of noradrenergic neurons in the locus coeruleus and cholinergic neurons in the septum. We found that exploration of new stimuli correlated negatively with numbers of noradrenergic neurons, whereas anxiety correlated positively with numbers of cholinergic neurons. The observed correlations suggest physiologically plausible links between structure and function and indicate that precise morphological estimates can be predictive for behavioral responses.

M3 - SCORING: Zeitschriftenaufsatz

VL - 191

SP - 280

EP - 284

JO - BEHAV BRAIN RES

JF - BEHAV BRAIN RES

SN - 0166-4328

IS - 2

M1 - 2

ER -