Novel biomarkers in cancer: The whole is greater than the sum of its parts

Timur R Samatov; Vladimir V Galatenko; Andreas Block; Maxim Yu Shkurnikov; Alexander G Tonevitsky; Udo Schumacher

doi:10.1016/j.semcancer.2016.09.002

Novel biomarkers in cancer: The whole is greater than the sum of its parts

Standard

Novel biomarkers in cancer: The whole is greater than the sum of its parts. / Samatov, Timur R; Galatenko, Vladimir V; Block, Andreas; Shkurnikov, Maxim Yu; Tonevitsky, Alexander G; Schumacher, Udo.

in: SEMIN CANCER BIOL, Jahrgang 45, 08.2017, S. 50-57.

Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Review › Forschung

Harvard

Samatov, TR, Galatenko, VV, Block, A, Shkurnikov, MY, Tonevitsky, AG & Schumacher, U 2017, 'Novel biomarkers in cancer: The whole is greater than the sum of its parts', SEMIN CANCER BIOL, Jg. 45, S. 50-57. https://doi.org/10.1016/j.semcancer.2016.09.002

APA

Samatov, T. R., Galatenko, V. V., Block, A., Shkurnikov, M. Y., Tonevitsky, A. G., & Schumacher, U. (2017). Novel biomarkers in cancer: The whole is greater than the sum of its parts. SEMIN CANCER BIOL, 45, 50-57. https://doi.org/10.1016/j.semcancer.2016.09.002

Vancouver

Samatov TR, Galatenko VV, Block A, Shkurnikov MY, Tonevitsky AG, Schumacher U. Novel biomarkers in cancer: The whole is greater than the sum of its parts. SEMIN CANCER BIOL. 2017 Aug;45:50-57. https://doi.org/10.1016/j.semcancer.2016.09.002

Bibtex

@article{11511d20fbbc4a30b29430855e7d0941,

title = "Novel biomarkers in cancer: The whole is greater than the sum of its parts",

abstract = "The major issues hampering progress in the treatment of cancer patients are distant metastases and drug resistance to chemotherapy. Metastasis formation is a very complex process, and looking at gene signatures alone is not enough to get deep insight into it. This paper reviews traditional and novel approaches to identify gene signature biomarkers and intratumoural fluid pressure both as a novel way of creating predictive markers and as an obstacle to cancer therapy. Finally recently developed in vitro systems to predict the response of individual patient derived cancer explants to chemotherapy are discussed.",

author = "Samatov, {Timur R} and Galatenko, {Vladimir V} and Andreas Block and Shkurnikov, {Maxim Yu} and Tonevitsky, {Alexander G} and Udo Schumacher",

note = "Copyright {\textcopyright} 2016. Published by Elsevier Ltd.",

year = "2017",

month = aug,

doi = "10.1016/j.semcancer.2016.09.002",

language = "English",

volume = "45",

pages = "50--57",

journal = "SEMIN CANCER BIOL",

issn = "1044-579X",

publisher = "Academic Press Inc.",

}

RIS

TY - JOUR

T1 - Novel biomarkers in cancer: The whole is greater than the sum of its parts

AU - Samatov, Timur R

AU - Galatenko, Vladimir V

AU - Block, Andreas

AU - Shkurnikov, Maxim Yu

AU - Tonevitsky, Alexander G

AU - Schumacher, Udo

PY - 2017/8

Y1 - 2017/8

N2 - The major issues hampering progress in the treatment of cancer patients are distant metastases and drug resistance to chemotherapy. Metastasis formation is a very complex process, and looking at gene signatures alone is not enough to get deep insight into it. This paper reviews traditional and novel approaches to identify gene signature biomarkers and intratumoural fluid pressure both as a novel way of creating predictive markers and as an obstacle to cancer therapy. Finally recently developed in vitro systems to predict the response of individual patient derived cancer explants to chemotherapy are discussed.

AB - The major issues hampering progress in the treatment of cancer patients are distant metastases and drug resistance to chemotherapy. Metastasis formation is a very complex process, and looking at gene signatures alone is not enough to get deep insight into it. This paper reviews traditional and novel approaches to identify gene signature biomarkers and intratumoural fluid pressure both as a novel way of creating predictive markers and as an obstacle to cancer therapy. Finally recently developed in vitro systems to predict the response of individual patient derived cancer explants to chemotherapy are discussed.

U2 - 10.1016/j.semcancer.2016.09.002

DO - 10.1016/j.semcancer.2016.09.002

M3 - SCORING: Review article

C2 - 27639751

VL - 45

SP - 50

EP - 57

JO - SEMIN CANCER BIOL

JF - SEMIN CANCER BIOL

SN - 1044-579X

ER -