Normal mast cell numbers in the tissues of AhR-deficient mice
Standard
Normal mast cell numbers in the tissues of AhR-deficient mice. / Pilz, Caroline; Feyerabend, Thorsten; Sonner, Jana; Redaelli, Chiara; Peter, Katharina; Kunze, Anja; Haas, Katharina; Esser, Charlotte; Schäkel, Knut; Wick, Wolfgang; Rodewald, Hans-Reimer; Lanz, Tobias V; Platten, Michael.
in: EXP DERMATOL, Jahrgang 25, Nr. 1, 01.2016, S. 62-3.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
Harvard
APA
Vancouver
Bibtex
}
RIS
TY - JOUR
T1 - Normal mast cell numbers in the tissues of AhR-deficient mice
AU - Pilz, Caroline
AU - Feyerabend, Thorsten
AU - Sonner, Jana
AU - Redaelli, Chiara
AU - Peter, Katharina
AU - Kunze, Anja
AU - Haas, Katharina
AU - Esser, Charlotte
AU - Schäkel, Knut
AU - Wick, Wolfgang
AU - Rodewald, Hans-Reimer
AU - Lanz, Tobias V
AU - Platten, Michael
N1 - © 2015 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
PY - 2016/1
Y1 - 2016/1
N2 - The transcription factor aryl hydrocarbon receptor (AhR) acts as an immunomodulatory molecule in several immune cell lineages. Recently, it has been implicated in development and maintenance of immune cells in barrier tissues such as skin and mucosa. To investigate its role on mast cell development and maintenance in skin, peritoneal exudate cells (PECs) and lymph nodes, we studied in depth their phenotype in AhR-deficient mice. Our findings do not provide any evidence for a suspected role of the AhR in mast cell homeostasis.
AB - The transcription factor aryl hydrocarbon receptor (AhR) acts as an immunomodulatory molecule in several immune cell lineages. Recently, it has been implicated in development and maintenance of immune cells in barrier tissues such as skin and mucosa. To investigate its role on mast cell development and maintenance in skin, peritoneal exudate cells (PECs) and lymph nodes, we studied in depth their phenotype in AhR-deficient mice. Our findings do not provide any evidence for a suspected role of the AhR in mast cell homeostasis.
KW - Animals
KW - Basic Helix-Loop-Helix Transcription Factors/genetics
KW - Cell Lineage
KW - Female
KW - Flow Cytometry
KW - Homeostasis
KW - Immune System
KW - Lymph Nodes/pathology
KW - Mast Cells/cytology
KW - Mice
KW - Mice, Inbred C57BL
KW - Mucous Membrane/metabolism
KW - Peritoneum/metabolism
KW - Phenotype
KW - Receptors, Aryl Hydrocarbon/genetics
KW - Skin/metabolism
U2 - 10.1111/exd.12864
DO - 10.1111/exd.12864
M3 - SCORING: Journal article
C2 - 26443189
VL - 25
SP - 62
EP - 63
JO - EXP DERMATOL
JF - EXP DERMATOL
SN - 0906-6705
IS - 1
ER -