Nociceptive stimulation induces expression of Arc/Arg3.1 in the spinal cord with a preference for neurons containing enkephalin.

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Nociceptive stimulation induces expression of Arc/Arg3.1 in the spinal cord with a preference for neurons containing enkephalin. / Hossaini, Mehdi; Jongen, Joost L M; Biesheuvel, Karla; Kuhl, Dietmar; Holstege, Jan C.

in: MOL PAIN, Jahrgang 6, 2010, S. 43.

Publikationen: SCORING: Beitrag in Fachzeitschrift/ZeitungSCORING: ZeitschriftenaufsatzForschungBegutachtung

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@article{2f4c33c067124cf19df959e56ad7b53c,
title = "Nociceptive stimulation induces expression of Arc/Arg3.1 in the spinal cord with a preference for neurons containing enkephalin.",
abstract = "In pain processing, long term synaptic changes play an important role, especially during chronic pain. The immediate early gene Arc/Arg3.1 has been widely implicated in mediating long-term plasticity in telencephalic regions, such as the hippocampus and cortex. Accordingly, Arc/Arg3.1 knockout (KO) mice show a deficit in long-term memory consolidation. Here, we identify expression of Arc/Arg3.1 in the rat spinal cord using immunohistochemistry and in situ hybridization following pain stimuli.",
author = "Mehdi Hossaini and Jongen, {Joost L M} and Karla Biesheuvel and Dietmar Kuhl and Holstege, {Jan C}",
year = "2010",
doi = "10.1186/1744-8069-6-43",
language = "Deutsch",
volume = "6",
pages = "43",

}

RIS

TY - JOUR

T1 - Nociceptive stimulation induces expression of Arc/Arg3.1 in the spinal cord with a preference for neurons containing enkephalin.

AU - Hossaini, Mehdi

AU - Jongen, Joost L M

AU - Biesheuvel, Karla

AU - Kuhl, Dietmar

AU - Holstege, Jan C

PY - 2010

Y1 - 2010

N2 - In pain processing, long term synaptic changes play an important role, especially during chronic pain. The immediate early gene Arc/Arg3.1 has been widely implicated in mediating long-term plasticity in telencephalic regions, such as the hippocampus and cortex. Accordingly, Arc/Arg3.1 knockout (KO) mice show a deficit in long-term memory consolidation. Here, we identify expression of Arc/Arg3.1 in the rat spinal cord using immunohistochemistry and in situ hybridization following pain stimuli.

AB - In pain processing, long term synaptic changes play an important role, especially during chronic pain. The immediate early gene Arc/Arg3.1 has been widely implicated in mediating long-term plasticity in telencephalic regions, such as the hippocampus and cortex. Accordingly, Arc/Arg3.1 knockout (KO) mice show a deficit in long-term memory consolidation. Here, we identify expression of Arc/Arg3.1 in the rat spinal cord using immunohistochemistry and in situ hybridization following pain stimuli.

U2 - 10.1186/1744-8069-6-43

DO - 10.1186/1744-8069-6-43

M3 - SCORING: Zeitschriftenaufsatz

VL - 6

SP - 43

ER -