Nimotuzumab treatment of malignant gliomas.
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Nimotuzumab treatment of malignant gliomas. / Bode, Udo; Massimino, Maura; Bach, Ferdinand; Zimmermann, Martina; Khuhlaeva, Elena; Westphal, Manfred; Fleischhack, Gudrun.
in: EXPERT OPIN BIOL TH, Jahrgang 12, Nr. 12, 12, 2012, S. 1649-1659.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Nimotuzumab treatment of malignant gliomas.
AU - Bode, Udo
AU - Massimino, Maura
AU - Bach, Ferdinand
AU - Zimmermann, Martina
AU - Khuhlaeva, Elena
AU - Westphal, Manfred
AU - Fleischhack, Gudrun
PY - 2012
Y1 - 2012
N2 - In spite of new alkylating medication and recently accumulated knowledge about genomics, the prognosis of malignant gliomas remains poor. The introduction of single substances interfering with tumour proliferation dynamics has been disappointing and the lessons learned indicate that a complicated network of proliferation needs time consuming, in-depth analysis in order to more specifically treat now distinguishable subgroups of a disease, which too long was thought of as a uniform entity.
AB - In spite of new alkylating medication and recently accumulated knowledge about genomics, the prognosis of malignant gliomas remains poor. The introduction of single substances interfering with tumour proliferation dynamics has been disappointing and the lessons learned indicate that a complicated network of proliferation needs time consuming, in-depth analysis in order to more specifically treat now distinguishable subgroups of a disease, which too long was thought of as a uniform entity.
KW - Adult
KW - Humans
KW - Child
KW - Clinical Trials as Topic
KW - Signal Transduction
KW - Antibodies, Monoclonal, Humanized/pharmacokinetics/pharmacology/therapeutic use
KW - Brain Neoplasms/drug therapy
KW - Glioma/drug therapy
KW - Adult
KW - Humans
KW - Child
KW - Clinical Trials as Topic
KW - Signal Transduction
KW - Antibodies, Monoclonal, Humanized/pharmacokinetics/pharmacology/therapeutic use
KW - Brain Neoplasms/drug therapy
KW - Glioma/drug therapy
M3 - SCORING: Journal article
VL - 12
SP - 1649
EP - 1659
JO - EXPERT OPIN BIOL TH
JF - EXPERT OPIN BIOL TH
SN - 1471-2598
IS - 12
M1 - 12
ER -