Neuroleptic-induced extrapyramidal symptoms are accompanied by cognitive dysfunction in schizophrenia.
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Neuroleptic-induced extrapyramidal symptoms are accompanied by cognitive dysfunction in schizophrenia. / Krausz, M; Moritz, Steffen; Naber, Dieter; Lambert, Martin; Andresen, B.
in: EUR PSYCHIAT, Jahrgang 14, Nr. 2, 2, 1999, S. 84-88.Publikationen: SCORING: Beitrag in Fachzeitschrift/Zeitung › SCORING: Zeitschriftenaufsatz › Forschung › Begutachtung
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TY - JOUR
T1 - Neuroleptic-induced extrapyramidal symptoms are accompanied by cognitive dysfunction in schizophrenia.
AU - Krausz, M
AU - Moritz, Steffen
AU - Naber, Dieter
AU - Lambert, Martin
AU - Andresen, B
PY - 1999
Y1 - 1999
N2 - Cognitive impairments in schizophrenics have been found to precede tardive dyskinesia and to co-exist with other motor deficits. However, little is yet known about the prevalence of cognitive disturbances in patients with neuroleptic-induced parkinsonism. From the literature on idiopathic parkinson, it was inferred that extrapyramidal symptoms (EPS) are accompanied by cognitive dysfunction. 85 schizophrenic in-patients were divided into EPS high and low scorers according to an established criterion (Simpson Angus Scale, cut-off score: 0.4). Cognitive impairments were assessed using a self-rating instrument measuring disturbances of information processing. Patients with high EPS exhibited significantly elevated scores in six of ten cognitive and perceptual subscales (t = 2.1-3.1) as compared to low EPS patients. It is concluded that high EPS patients suffer from cognitive disturbances which are assumed to possess high relevance for both psycho-social and medical treatment. Cognitive problems may, when not considered, disturb compliance, insight of illness and transfer of learnt skills into everyday life.
AB - Cognitive impairments in schizophrenics have been found to precede tardive dyskinesia and to co-exist with other motor deficits. However, little is yet known about the prevalence of cognitive disturbances in patients with neuroleptic-induced parkinsonism. From the literature on idiopathic parkinson, it was inferred that extrapyramidal symptoms (EPS) are accompanied by cognitive dysfunction. 85 schizophrenic in-patients were divided into EPS high and low scorers according to an established criterion (Simpson Angus Scale, cut-off score: 0.4). Cognitive impairments were assessed using a self-rating instrument measuring disturbances of information processing. Patients with high EPS exhibited significantly elevated scores in six of ten cognitive and perceptual subscales (t = 2.1-3.1) as compared to low EPS patients. It is concluded that high EPS patients suffer from cognitive disturbances which are assumed to possess high relevance for both psycho-social and medical treatment. Cognitive problems may, when not considered, disturb compliance, insight of illness and transfer of learnt skills into everyday life.
M3 - SCORING: Zeitschriftenaufsatz
VL - 14
SP - 84
EP - 88
JO - EUR PSYCHIAT
JF - EUR PSYCHIAT
SN - 0924-9338
IS - 2
M1 - 2
ER -
